Gene description for JAM3
Gene name	junctional adhesion molecule 3
Gene symbol	JAM3
Other names/aliases	JAM-2 JAM-3 JAM-C JAMC
Species	Homo sapiens
Database cross references - JAM3
ExoCarta	ExoCarta_83700
Entrez Gene	83700
HGNC	15532
MIM	606871
UniProt	Q9BX67
JAM3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for JAM3

Molecular Function     protein heterodimerization activity GO:0046982 IEA     protein homodimerization activity GO:0042803 IEA     integrin binding GO:0005178 IPI     protein binding GO:0005515 IPI Biological Process     myelination GO:0042552 IEA     spermatid development GO:0007286 IEA     myeloid progenitor cell differentiation GO:0002318 IEA     leukocyte migration involved in inflammatory response GO:0002523 IEA     blood coagulation GO:0007596 TAS     transmission of nerve impulse GO:0019226 IEA     cell-matrix adhesion GO:0007160 IEA     extracellular matrix organization GO:0030198 TAS     establishment of cell polarity GO:0030010 IEA     regulation of neutrophil chemotaxis GO:0090022 IDA     axon regeneration GO:0031103 IEA     angiogenesis GO:0001525 IDA     regulation of actin cytoskeleton organization by cell-cell adhesion GO:0090138 IEA     neutrophil homeostasis GO:0001780 IEA     adaptive immune response GO:0002250 IEA     leukocyte migration GO:0050900 TAS Subcellular Localization     Golgi apparatus GO:0005794 IDA     paranodal junction GO:0033010 IEA     bicellular tight junction GO:0005923 IEA     desmosome GO:0030057 IDA     extracellular space GO:0005615 IDA     integral component of membrane GO:0016021 IEA     plasma membrane GO:0005886 TAS     Schmidt-Lanterman incisure GO:0043220 IEA     cell-cell contact zone GO:0044291 IDA