Gene description for MCAM
Gene name melanoma cell adhesion molecule
Gene symbol MCAM
Other names/aliases CD146
MUC18
Species Homo sapiens
 Database cross references - MCAM
ExoCarta ExoCarta_4162
Vesiclepedia VP_4162
Entrez Gene 4162
HGNC 6934
MIM 155735
UniProt P43121  
 MCAM identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Melanoma cells 15478216    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for MCAM
Molecular Function
    laminin receptor activity GO:0005055 IBA
    protein binding GO:0005515 IPI
Biological Process
    angiogenesis GO:0001525 IBA
    angiogenesis GO:0001525 IDA
    glomerular filtration GO:0003094 IEP
    cell adhesion GO:0007155 IEA
    anatomical structure morphogenesis GO:0009653 TAS
    positive regulation of cell migration GO:0030335 IEA
    vascular wound healing GO:0061042 IEP
Subcellular Localization
    extracellular region GO:0005576 HDA
    extracellular space GO:0005615 IEA
    plasma membrane GO:0005886 IBA
    focal adhesion GO:0005925 HDA
    external side of plasma membrane GO:0009897 IDA
 Experiment description of studies that identified MCAM in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 12
MISEV standards
✔
EM
Biophysical techniques
✔
MHCI
Enriched markers
✔
CANX|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 15478216    
Organism Homo sapiens
Experiment description Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.
Authors "Mears R, Craven RA, Hanrahan S, Totty N, Upton C, Young SL, Patel P, Selby PJ, Banks RE"
Journal name PROTEOMICS
Publication year 2004
Sample Melanoma cells
Sample name MeWo
SK-MEL-28
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [4700 Proteomics Analyzer]
Western blotting
17
Experiment ID 200
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
25
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for MCAM
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
Proximity Label-MS Homo sapiens
2 ROBO1 6091
Proximity Label-MS Homo sapiens
3 GJD3  
Proximity Label-MS Homo sapiens
4 UTRN 7402
Proximity Label-MS Homo sapiens
5 CNNM4 26504
Proximity Label-MS Homo sapiens
6 SPRED2 200734
Proximity Label-MS Homo sapiens
7 LLGL1 3996
Proximity Label-MS Homo sapiens
8 SLC23A2 9962
Proximity Label-MS Homo sapiens
9 SH3BP4 23677
Proximity Label-MS Homo sapiens
10 JPH1 56704
Proximity Label-MS Homo sapiens
11 MAP4K4 9448
Proximity Label-MS Homo sapiens
12 ATP11C 286410
Affinity Capture-MS Homo sapiens
13 ANKRD50 57182
Proximity Label-MS Homo sapiens
14 SLC5A6 8884
Proximity Label-MS Homo sapiens
15 USP6NL 9712
Proximity Label-MS Homo sapiens
16 NDRG1 10397
Proximity Label-MS Homo sapiens
17 PACS1 55690
Proximity Label-MS Homo sapiens
18 RAI14 26064
Proximity Label-MS Homo sapiens
19 SRC 6714
Proximity Label-MS Homo sapiens
20 FAM129A 116496
Proximity Label-MS Homo sapiens
21 SCARB1 949
Proximity Label-MS Homo sapiens
22 MARCKSL1 65108
Proximity Label-MS Homo sapiens
23 SLC6A15 55117
Proximity Label-MS Homo sapiens
24 TFRC 7037
Proximity Label-MS Homo sapiens
25 SLC25A3 5250
Proximity Label-MS Homo sapiens
26 NOTCH2 4853
Proximity Label-MS Homo sapiens
27 AP3M1 26985
Proximity Label-MS Homo sapiens
28 DAG1 1605
Proximity Label-MS Homo sapiens
29 LRRC57 255252
Proximity Label-MS Homo sapiens
30 LZTS1  
Proximity Label-MS Homo sapiens
31 MCAM 4162
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
32 EFR3B  
Proximity Label-MS Homo sapiens
33 PDXDC1 23042
Proximity Label-MS Homo sapiens
34 FYN 2534
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
35 SLC43A3 29015
Proximity Label-MS Homo sapiens
36 GORASP2 26003
Proximity Label-MS Homo sapiens
37 CNTN1 1272
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 PLEKHO2 80301
Proximity Label-MS Homo sapiens
39 PICALM 8301
Proximity Label-MS Homo sapiens
40 CTDSPL 10217
Proximity Label-MS Homo sapiens
41 BIN1 274
Proximity Label-MS Homo sapiens
42 ZDHHC20 253832
Proximity Label-MS Homo sapiens
43 ANLN 54443
Proximity Label-MS Homo sapiens
44 PHLPP1  
Proximity Label-MS Homo sapiens
45 CSNK1G3 1456
Proximity Label-MS Homo sapiens
46 CTNNA2 1496
Proximity Label-MS Homo sapiens
47 PALM2  
Proximity Label-MS Homo sapiens
48 EPB41L1 2036
Proximity Label-MS Homo sapiens
49 ANO6 196527
Proximity Label-MS Homo sapiens
50 ARHGAP32  
Proximity Label-MS Homo sapiens
51 FAM129B 64855
Proximity Label-MS Homo sapiens
52 CD22 933
Proximity Label-MS Homo sapiens
53 CDCA3 83461
Proximity Label-MS Homo sapiens
54 RALB 5899
Proximity Label-MS Homo sapiens
55 SCAMP1 9522
Proximity Label-MS Homo sapiens
56 ERBB2IP 55914
Proximity Label-MS Homo sapiens
57 ADCY3 109
Proximity Label-MS Homo sapiens
58 DLG1 1739
Proximity Label-MS Homo sapiens
59 SRGAP2 23380
Proximity Label-MS Homo sapiens
60 DIP2A 23181
Proximity Label-MS Homo sapiens
61 SNX9 51429
Proximity Label-MS Homo sapiens
62 WLS 79971
Proximity Label-MS Homo sapiens
63 GNAS 2778
Proximity Label-MS Homo sapiens
64 TMEM237 65062
Proximity Label-MS Homo sapiens
65 IGSF3 3321
Proximity Label-MS Homo sapiens
66 SPRY1 10252
Proximity Label-MS Homo sapiens
67 MPZL1 9019
Proximity Label-MS Homo sapiens
68 LAMA4 3910
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 ATP6V0A1 535
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 CTNNA1 1495
Proximity Label-MS Homo sapiens
71 LGALS8 3964
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 TRPV4 59341
Proximity Label-MS Homo sapiens
73 KIDINS220 57498
Proximity Label-MS Homo sapiens
74 GAS7  
Proximity Label-MS Homo sapiens
75 CDC42EP4  
Proximity Label-MS Homo sapiens
76 FLVCR1 28982
Proximity Label-MS Homo sapiens
77 GJC1 10052
Proximity Label-MS Homo sapiens
78 GPRIN3  
Proximity Label-MS Homo sapiens
79 RPS27A 6233
Proximity Label-MS Homo sapiens
80 PSD3 23362
Proximity Label-MS Homo sapiens
81 DAB2 1601
Proximity Label-MS Homo sapiens
82 SLC35A2  
Proximity Label-MS Homo sapiens
83 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
84 SHROOM1 134549
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
85 S100A10 6281
Proximity Label-MS Homo sapiens
86 RASA3 22821
Proximity Label-MS Homo sapiens
87 ELMOD3  
Proximity Label-MS Homo sapiens
88 FMNL3 91010
Proximity Label-MS Homo sapiens
89 WWP2 11060
Proximity Label-MS Homo sapiens
90 RAB2A 5862
Proximity Label-MS Homo sapiens
91 PHACTR4 65979
Proximity Label-MS Homo sapiens
92 RAB13 5872
Proximity Label-MS Homo sapiens
93 RAB11A 8766
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
94 C1orf21  
Proximity Label-MS Homo sapiens
95 EPHA2 1969
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
96 CISD2 493856
Proximity Label-MS Homo sapiens
97 RAB5C 5878
Proximity Label-MS Homo sapiens
98 VANGL1 81839
Proximity Label-MS Homo sapiens
99 MPZ  
Proximity Label-MS Homo sapiens
100 SNAP29 9342
Proximity Label-MS Homo sapiens
101 CTNND1 1500
Proximity Label-MS Homo sapiens
102 PTPRF 5792
Proximity Label-MS Homo sapiens
103 P2RX7 5027
Proximity Label-MS Homo sapiens
104 KLC2 64837
Proximity Label-MS Homo sapiens
105 LAMP3  
Proximity Label-MS Homo sapiens
106 GJA1 2697
Proximity Label-MS Homo sapiens
107 EHD3 30845
Proximity Label-MS Homo sapiens
108 ADRB2  
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
109 RASAL2 9462
Proximity Label-MS Homo sapiens
110 PACSIN2 11252
Proximity Label-MS Homo sapiens
111 SPTLC1 10558
Proximity Label-MS Homo sapiens
112 LGALS1 3956
Affinity Capture-MS Homo sapiens
113 PHLDB1 23187
Proximity Label-MS Homo sapiens
114 CNP 1267
Proximity Label-MS Homo sapiens
115 ROCK2 9475
Proximity Label-MS Homo sapiens
116 VAMP2 6844
Proximity Label-MS Homo sapiens
117 IFNGR1 3459
Proximity Label-MS Homo sapiens
118 SCARF2 91179
Proximity Label-MS Homo sapiens
119 VANGL2  
Proximity Label-MS Homo sapiens
120 IL6ST 3572
Proximity Label-MS Homo sapiens
121 FERMT3 83706
Proximity Label-MS Homo sapiens
122 AFAP1L2 84632
Proximity Label-MS Homo sapiens
123 ADAM9 8754
Proximity Label-MS Homo sapiens
124 TNIK 23043
Proximity Label-MS Homo sapiens
125 MAP4K5 11183
Proximity Label-MS Homo sapiens
126 PCNXL3 399909
Proximity Label-MS Homo sapiens
127 STEAP3 55240
Proximity Label-MS Homo sapiens
128 RHOJ 57381
Proximity Label-MS Homo sapiens
129 PTPN14 5784
Proximity Label-MS Homo sapiens
130 MPP1 4354
Proximity Label-MS Homo sapiens
131 SLC7A11 23657
Proximity Label-MS Homo sapiens
132 ABCC5 10057
Proximity Label-MS Homo sapiens
133 PTPN3  
Proximity Label-MS Homo sapiens
134 AGAP1  
Proximity Label-MS Homo sapiens
135 DAAM2 23500
Proximity Label-MS Homo sapiens
136 BSG 682
Proximity Label-MS Homo sapiens
137 SLC1A5 6510
Proximity Label-MS Homo sapiens
138 C10orf11  
Proximity Label-MS Homo sapiens
139 FLRT2 23768
Proximity Label-MS Homo sapiens
140 IL1RAP 3556
Proximity Label-MS Homo sapiens
141 CDK5 1020
Proximity Label-MS Homo sapiens
142 STOM 2040
Proximity Label-MS Homo sapiens
143 LYN 4067
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
144 JAM3 83700
Proximity Label-MS Homo sapiens
145 RAP1B 5908
Proximity Label-MS Homo sapiens
146 RELL1 768211
Proximity Label-MS Homo sapiens
147 LIN7C 55327
Proximity Label-MS Homo sapiens
148 SLC9A1 6548
Proximity Label-MS Homo sapiens
149 TRPM7 54822
Proximity Label-MS Homo sapiens
150 LAMP1 3916
Proximity Label-MS Homo sapiens
151 EHBP1L1 254102
Proximity Label-MS Homo sapiens
152 SLC12A4 6560
Proximity Label-MS Homo sapiens
153 FLRT3 23767
Proximity Label-MS Homo sapiens
154 GYPC 2995
Proximity Label-MS Homo sapiens
155 MINK1 50488
Proximity Label-MS Homo sapiens
156 DIP2B 57609
Proximity Label-MS Homo sapiens
157 STXBP5 134957
Proximity Label-MS Homo sapiens
158 ICAM1 3383
Proximity Label-MS Homo sapiens
159 RAB5A 5868
Proximity Label-MS Homo sapiens
160 ADCY9 115
Proximity Label-MS Homo sapiens
161 CDC42EP1 11135
Proximity Label-MS Homo sapiens
162 SLC26A2 1836
Proximity Label-MS Homo sapiens
163 RICTOR 253260
Proximity Label-MS Homo sapiens
164 TNPO3 23534
Affinity Capture-MS Homo sapiens
165 PACSIN3 29763
Proximity Label-MS Homo sapiens
166 HSP90AA5P 730211
Co-fractionation Homo sapiens
167 NRP2 8828
Proximity Label-MS Homo sapiens
168 SPTBN1 6711
Proximity Label-MS Homo sapiens
169 GAB1  
Proximity Label-MS Homo sapiens
170 PLEKHA5 54477
Proximity Label-MS Homo sapiens
171 BMPR2 659
Proximity Label-MS Homo sapiens
172 JAK1 3716
Proximity Label-MS Homo sapiens
173 SLC3A2 6520
Proximity Label-MS Homo sapiens
174 FBXO2 26232
Affinity Capture-MS Homo sapiens
175 PKP4 8502
Proximity Label-MS Homo sapiens
176 MICALL1 85377
Proximity Label-MS Homo sapiens
177 VRK2 7444
Proximity Label-MS Homo sapiens
178 RHOB 388
Proximity Label-MS Homo sapiens
179 WDR44 54521
Proximity Label-MS Homo sapiens
180 CCDC88A 55704
Proximity Label-MS Homo sapiens
181 LEMD3  
Proximity Label-MS Homo sapiens
182 CPNE8 144402
Proximity Label-MS Homo sapiens
183 CD44 960
Proximity Label-MS Homo sapiens
184 FRMD6 122786
Proximity Label-MS Homo sapiens
185 SLC16A1 6566
Proximity Label-MS Homo sapiens
186 MARK3 4140
Proximity Label-MS Homo sapiens
187 PLXNB2 23654
Proximity Label-MS Homo sapiens
188 SLC38A2 54407
Proximity Label-MS Homo sapiens
189 VDAC3 7419
Co-fractionation Homo sapiens
190 XPR1 9213
Proximity Label-MS Homo sapiens
191 KEAP1 9817
Proximity Label-MS Homo sapiens
192 PPAP2B 8613
Proximity Label-MS Homo sapiens
193 UGCG 7357
Proximity Label-MS Homo sapiens
194 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
195 PLSCR3 57048
Proximity Label-MS Homo sapiens
196 EPHA3 2042
Proximity Label-MS Homo sapiens
197 LPCAT2 54947
Proximity Label-MS Homo sapiens
198 ABI2 10152
Proximity Label-MS Homo sapiens
199 EPB41L3 23136
Proximity Label-MS Homo sapiens
200 STX3 6809
Proximity Label-MS Homo sapiens
201 ATP1A1 476
Proximity Label-MS Homo sapiens
202 SLC9A3R1 9368
Proximity Label-MS Homo sapiens
203 YKT6 10652
Proximity Label-MS Homo sapiens
204 C2CD5 9847
Proximity Label-MS Homo sapiens
205 VAMP5 10791
Proximity Label-MS Homo sapiens
206 ATP6V0A2 23545
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
207 ANK3  
Proximity Label-MS Homo sapiens
208 GNAI3 2773
Proximity Label-MS Homo sapiens
209 PTRF 284119
Proximity Label-MS Homo sapiens
210 RAB23 51715
Proximity Label-MS Homo sapiens
211 STRA6 64220
Proximity Label-MS Homo sapiens
212 PTPRG 5793
Proximity Label-MS Homo sapiens
213 SGCE 8910
Proximity Label-MS Homo sapiens
214 AFD1  
Proximity Label-MS Homo sapiens
215 CLCN7 1186
Proximity Label-MS Homo sapiens
216 C2CD2L 9854
Proximity Label-MS Homo sapiens
217 ZDHHC5 25921
Proximity Label-MS Homo sapiens
218 TBC1D10A 83874
Proximity Label-MS Homo sapiens
219 MARCKS 4082
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
220 GULP1 51454
Proximity Label-MS Homo sapiens
221 WASF2 10163
Proximity Label-MS Homo sapiens
222 EFR3A 23167
Proximity Label-MS Homo sapiens
223 EPB41L5 57669
Proximity Label-MS Homo sapiens
224 CABLES1  
Proximity Label-MS Homo sapiens
225 ADD3 120
Proximity Label-MS Homo sapiens
226 SHB 6461
Proximity Label-MS Homo sapiens
227 STX4 6810
Proximity Label-MS Homo sapiens
228 RAPH1 65059
Proximity Label-MS Homo sapiens
229 GNG12 55970
Proximity Label-MS Homo sapiens
230 RDX 5962
Proximity Label-MS Homo sapiens
231 PAK4 10298
Proximity Label-MS Homo sapiens
232 TAOK3 51347
Proximity Label-MS Homo sapiens
233 NUMBL 9253
Proximity Label-MS Homo sapiens
234 IQGAP1 8826
Proximity Label-MS Homo sapiens
235 DMD 1756
Proximity Label-MS Homo sapiens
236 RHBDF1 64285
Proximity Label-MS Homo sapiens
237 DLG2 1740
Proximity Label-MS Homo sapiens
238 ITGA4 3676
Proximity Label-MS Homo sapiens
239 STXBP3 6814
Proximity Label-MS Homo sapiens
240 ALCAM 214
Proximity Label-MS Homo sapiens
241 SNAP23 8773
Proximity Label-MS Homo sapiens
242 SYTL4 94121
Proximity Label-MS Homo sapiens
243 PKN2 5586
Proximity Label-MS Homo sapiens
244 ESYT2 57488
Proximity Label-MS Homo sapiens
245 GPRIN1 114787
Proximity Label-MS Homo sapiens
246 EHD1 10938
Proximity Label-MS Homo sapiens
247 APPL1 26060
Proximity Label-MS Homo sapiens
248 SLC30A1 7779
Proximity Label-MS Homo sapiens
249 NF2 4771
Proximity Label-MS Homo sapiens
250 BTN3A2 11118
Proximity Label-MS Homo sapiens
251 CXADR 1525
Proximity Label-MS Homo sapiens
252 CHCHD3 54927
Proximity Label-MS Homo sapiens
253 RALA 5898
Proximity Label-MS Homo sapiens
254 CSPG4 1464
Proximity Label-MS Homo sapiens
255 SLC16A3 9123
Proximity Label-MS Homo sapiens
256 NUMB 8650
Proximity Label-MS Homo sapiens
257 DIRAS3  
Proximity Label-MS Homo sapiens
258 SLC6A6 6533
Proximity Label-MS Homo sapiens
259 GNAI2 2771
Proximity Label-MS Homo sapiens
260 ARL13B 200894
Proximity Label-MS Homo sapiens
261 PIP5K1C  
Proximity Label-MS Homo sapiens
262 LATS2 26524
Proximity Label-MS Homo sapiens
263 SNTB1 6641
Proximity Label-MS Homo sapiens
264 SLC4A7 9497
Proximity Label-MS Homo sapiens
265 PCDH1 5097
Proximity Label-MS Homo sapiens
266 FERMT2 10979
Proximity Label-MS Homo sapiens
267 PTPRA 5786
Proximity Label-MS Homo sapiens
268 SIRPA 140885
Proximity Label-MS Homo sapiens
269 VAMP3 9341
Proximity Label-MS Homo sapiens
270 ITM2C 81618
Proximity Label-MS Homo sapiens
271 CLEC4A  
Affinity Capture-MS Homo sapiens
272 CYFIP2 26999
Proximity Label-MS Homo sapiens
273 BAIAP2L1 55971
Proximity Label-MS Homo sapiens
274 KIF26B  
Proximity Label-MS Homo sapiens
275 CAND1 55832
Proximity Label-MS Homo sapiens
276 CDC42BPA 8476
Proximity Label-MS Homo sapiens
277 PTPN13 5783
Proximity Label-MS Homo sapiens
278 GNB2 2783
Proximity Label-MS Homo sapiens
279 RAB9A 9367
Proximity Label-MS Homo sapiens
280 EPB41 2035
Proximity Label-MS Homo sapiens
281 KCNN4 3783
Proximity Label-MS Homo sapiens
282 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
283 MSN 4478
Proximity Label-MS Homo sapiens
284 HLA-A 3105
Proximity Label-MS Homo sapiens
285 ARHGAP31 57514
Proximity Label-MS Homo sapiens
286 SPRY2 10253
Proximity Label-MS Homo sapiens
287 ATP7A 538
Proximity Label-MS Homo sapiens
288 CASKIN2  
Proximity Label-MS Homo sapiens
289 FLOT1 10211
Proximity Label-MS Homo sapiens
290 PIP5K1A 8394
Proximity Label-MS Homo sapiens
291 DEPDC1B 55789
Proximity Label-MS Homo sapiens
292 PVRL2 5819
Proximity Label-MS Homo sapiens
293 ABCB6 10058
Co-fractionation Homo sapiens
294 CTDSP1 58190
Proximity Label-MS Homo sapiens
295 FAM171B  
Proximity Label-MS Homo sapiens
296 VAMP4 8674
Proximity Label-MS Homo sapiens
297 EFNB1 1947
Proximity Label-MS Homo sapiens
298 ERGIC1 57222
Proximity Label-MS Homo sapiens
299 C11orf52 91894
Proximity Label-MS Homo sapiens
300 NF1 4763
Proximity Label-MS Homo sapiens
301 FRS2 10818
Proximity Label-MS Homo sapiens
302 RAB7A 7879
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
303 SLC1A4 6509
Proximity Label-MS Homo sapiens
304 TULP3 7289
Proximity Label-MS Homo sapiens
305 EZR 7430
Proximity Label-MS Homo sapiens
306 CYFIP1 23191
Proximity Label-MS Homo sapiens
307 ITGB5 3693
Proximity Label-MS Homo sapiens
308 SPRED1 161742
Proximity Label-MS Homo sapiens
309 CAV1 857
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
310 PVRL3 25945
Proximity Label-MS Homo sapiens
311 HLA-C 3107
Proximity Label-MS Homo sapiens
312 C1orf198 84886
Proximity Label-MS Homo sapiens
313 PARD3B 117583
Proximity Label-MS Homo sapiens
314 SNX3 8724
Proximity Label-MS Homo sapiens
315 RFTN1 23180
Proximity Label-MS Homo sapiens
316 CDC42BPB 9578
Proximity Label-MS Homo sapiens
317 VTI1B 10490
Proximity Label-MS Homo sapiens
318 CST5 1473
Affinity Capture-MS Homo sapiens
319 AKAP12 9590
Proximity Label-MS Homo sapiens
320 CSNK1G2 1455
Proximity Label-MS Homo sapiens
321 DST 667
Proximity Label-MS Homo sapiens
322 HSPA1L 3305
Co-fractionation Homo sapiens
323 SASH1 23328
Proximity Label-MS Homo sapiens
324 LAMP2 3920
Proximity Label-MS Homo sapiens
325 SNX6 58533
Proximity Label-MS Homo sapiens
326 SLC12A2 6558
Proximity Label-MS Homo sapiens
327 AGAP3 116988
Proximity Label-MS Homo sapiens
328 TMPO 7112
Proximity Label-MS Homo sapiens
329 KIAA1429 25962
Affinity Capture-MS Homo sapiens
330 MARK2 2011
Proximity Label-MS Homo sapiens
331 SLC20A1 6574
Proximity Label-MS Homo sapiens
332 SLC39A10 57181
Proximity Label-MS Homo sapiens
333 WDR20 91833
Proximity Label-MS Homo sapiens
334 STIM2 57620
Proximity Label-MS Homo sapiens
335 YES1 7525
Proximity Label-MS Homo sapiens
336 SCRIB 23513
Proximity Label-MS Homo sapiens
337 STX7 8417
Proximity Label-MS Homo sapiens
338 ADD1 118
Proximity Label-MS Homo sapiens
339 TIAM1  
Proximity Label-MS Homo sapiens
340 SVIP 258010
Proximity Label-MS Homo sapiens
341 PEAK1 79834
Proximity Label-MS Homo sapiens
342 VAT1 10493
Proximity Label-MS Homo sapiens
343 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
344 RAB35 11021
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 MTMR10 54893
Proximity Label-MS Homo sapiens
346 ERBB2 2064
Proximity Label-MS Homo sapiens
347 TMEM2 23670
Proximity Label-MS Homo sapiens
348 CPNE3 8895
Proximity Label-MS Homo sapiens
349 AHCYL1 10768
Proximity Label-MS Homo sapiens
350 LAMTOR1 55004
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
351 PLCB1 23236
Proximity Label-MS Homo sapiens
352 CASK 8573
Proximity Label-MS Homo sapiens
353 E2F4  
Affinity Capture-MS Homo sapiens
354 ITGB3 3690
Proximity Label-MS Homo sapiens
355 ZDHHC8 29801
Proximity Label-MS Homo sapiens
356 INPP4B 8821
Proximity Label-MS Homo sapiens
357 ERBB3 2065
Proximity Label-MS Homo sapiens
358 TNFRSF10B 8795
Proximity Label-MS Homo sapiens
359 CNNM3 26505
Proximity Label-MS Homo sapiens
360 PAG1 55824
Proximity Label-MS Homo sapiens
361 C19orf26 255057
Proximity Label-MS Homo sapiens
362 SPRY4 81848
Proximity Label-MS Homo sapiens
363 GOPC 57120
Proximity Label-MS Homo sapiens
364 ATP2B4 493
Proximity Label-MS Homo sapiens
365 TBC1D10B 26000
Proximity Label-MS Homo sapiens
366 RPS6KA1 6195
Proximity Label-MS Homo sapiens
367 SYT11 23208
Proximity Label-MS Homo sapiens
368 STK10 6793
Proximity Label-MS Homo sapiens
369 PTPRM 5797
Proximity Label-MS Homo sapiens
370 CYB5B 80777
Co-fractionation Homo sapiens
371 TMEM199  
Proximity Label-MS Homo sapiens
372 PANX1 24145
Proximity Label-MS Homo sapiens
373 SLC39A6 25800
Proximity Label-MS Homo sapiens
374 RAB34 83871
Proximity Label-MS Homo sapiens
375 ATP2B1 490
Proximity Label-MS Homo sapiens
376 SLC20A2 6575
Proximity Label-MS Homo sapiens
377 STXBP1 6812
Proximity Label-MS Homo sapiens
378 NPTN 27020
Proximity Label-MS Homo sapiens
379 CTNNB1 1499
Proximity Label-MS Homo sapiens
380 DOCK10 55619
Proximity Label-MS Homo sapiens
381 SLC9A3R2 9351
Proximity Label-MS Homo sapiens
382 SLC7A5 8140
Proximity Label-MS Homo sapiens
383 ARF6 382
Proximity Label-MS Homo sapiens
384 SEPT11 55752
Proximity Label-MS Homo sapiens
385 UACA 55075
Proximity Label-MS Homo sapiens
386 EHBP1 23301
Proximity Label-MS Homo sapiens
387 ERP44 23071
Proximity Label-MS Homo sapiens
388 LZTS2 84445
Proximity Label-MS Homo sapiens
389 KIRREL 55243
Proximity Label-MS Homo sapiens
390 MYO6 4646
Proximity Label-MS Homo sapiens
391 PTPRK 5796
Proximity Label-MS Homo sapiens
392 MYOF 26509
Proximity Label-MS Homo sapiens
393 PPFIBP1 8496
Proximity Label-MS Homo sapiens
394 DCUN1D3 123879
Proximity Label-MS Homo sapiens
395 VDAC1 7416
Co-fractionation Homo sapiens
396 KRAS 3845
Proximity Label-MS Homo sapiens
397 PPFIA1 8500
Proximity Label-MS Homo sapiens
398 FARP1 10160
Proximity Label-MS Homo sapiens
399 DOCK9 23348
Proximity Label-MS Homo sapiens
400 ATP2B3 492
Proximity Label-MS Homo sapiens
401 FMN1 342184
Proximity Label-MS Homo sapiens
402 HLA-G 3135
Proximity Label-MS Homo sapiens
403 ROCK1 6093
Proximity Label-MS Homo sapiens
404 EHD4 30844
Proximity Label-MS Homo sapiens
405 SNTB2 6645
Proximity Label-MS Homo sapiens
406 PARD6G 84552
Proximity Label-MS Homo sapiens
407 RP2 6102
Proximity Label-MS Homo sapiens
408 EPB41L2 2037
Proximity Label-MS Homo sapiens
409 ITGAV 3685
Proximity Label-MS Homo sapiens
410 DDR2 4921
Proximity Label-MS Homo sapiens
411 PTPRS 5802
Proximity Label-MS Homo sapiens
412 RPL23 9349
Proximity Label-MS Homo sapiens
413 SLC6A8 6535
Proximity Label-MS Homo sapiens
414 DOCK7 85440
Proximity Label-MS Homo sapiens
415 PTPRJ 5795
Proximity Label-MS Homo sapiens
416 ESYT1 23344
Proximity Label-MS Homo sapiens
417 DSG2 1829
Proximity Label-MS Homo sapiens
418 BAI1  
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here