Experiment description of studies that identified DLG2 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for DLG2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 DLGAP1   Affinity Capture-Western Homo sapiens 2 NLGN1   Two-hybrid Homo sapiens 3 LIN7A 8825 Invitro Homo sapiens 4 NLGN3   Two-hybrid Homo sapiens 5 DLG1 1739 Invivo Homo sapiens 6 GUCY1A2   Invitro Homo sapiens 7 GRIN2A   Two-hybrid Homo sapiens 8 DYNLL2 140735 Affinity Capture-Western Homo sapiens 9 ATP2B4 493 Invitro Homo sapiens Invivo Homo sapiens 10 ERBB4 2066 Two-hybrid Homo sapiens 11 SEMA4C 54910 Two-hybrid Homo sapiens 12 GRIN2B   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 13 KCNJ12 3768 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 14 DYNLL1 8655 Affinity Capture-Western Homo sapiens 15 KCNJ4   Affinity Capture-Western Homo sapiens 16 NLGN2 57555 Two-hybrid Homo sapiens 17 LRP2 4036 Two-hybrid Homo sapiens 18 NOS1   Invitro Homo sapiens Two-hybrid Homo sapiens 19 ATP2B2 491 Invitro Homo sapiens Invivo Homo sapiens 20 DLG4   Affinity Capture-Western Homo sapiens 21 KCNA4   Affinity Capture-Western Homo sapiens View the network

Pathways in which DLG2 is involved

No pathways found