Gene description for TFAM
Gene name transcription factor A, mitochondrial
Gene symbol TFAM
Other names/aliases MTTF1
MTTFA
TCF6
TCF6L1
TCF6L2
TCF6L3
Species Homo sapiens
 Database cross references - TFAM
ExoCarta ExoCarta_7019
Vesiclepedia VP_7019
Entrez Gene 7019
HGNC 11741
MIM 600438
UniProt Q00059  
 TFAM identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for TFAM
Molecular Function
    transcription cis-regulatory region binding GO:0000976 IBA
    mitochondrial promoter sequence-specific DNA binding GO:0001018 IDA
    transcription coactivator binding GO:0001223 IEA
    chromatin binding GO:0003682 IDA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    DNA binding, bending GO:0008301 IBA
    heat shock protein binding GO:0031072 IEA
    mitochondrial transcription factor activity GO:0034246 IMP
    sequence-specific DNA binding GO:0043565 IDA
Biological Process
    response to hypoxia GO:0001666 IEA
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    mitochondrial transcription GO:0006390 IMP
    transcription initiation at mitochondrial promoter GO:0006391 IBA
    transcription initiation at mitochondrial promoter GO:0006391 IDA
    response to nutrient GO:0007584 IEA
    mitochondrial respiratory chain complex assembly GO:0033108 IEA
    positive regulation of DNA-templated transcription GO:0045893 IDA
Subcellular Localization
    nucleus GO:0005634 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 IDA
    mitochondrial matrix GO:0005759 NAS
    mitochondrial matrix GO:0005759 TAS
    cytosol GO:0005829 TAS
    protein-containing complex GO:0032991 IDA
    mitochondrial nucleoid GO:0042645 IDA
 Experiment description of studies that identified TFAM in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for TFAM
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 CDC14B 8555
Affinity Capture-MS Homo sapiens
4 COX5A 9377
Co-fractionation Homo sapiens
5 RIT1 6016
Negative Genetic Homo sapiens
6 AFG3L2 10939
Proximity Label-MS Homo sapiens
7 MRPS35 60488
Proximity Label-MS Homo sapiens
8 FOXA1  
Affinity Capture-MS Homo sapiens
9 DBT 1629
Proximity Label-MS Homo sapiens
10 IARS2 55699
Proximity Label-MS Homo sapiens
11 GLUD1 2746
Proximity Label-MS Homo sapiens
12 MRPL48  
Proximity Label-MS Homo sapiens
13 MRPS26 64949
Proximity Label-MS Homo sapiens
14 ZMYND8 23613
Affinity Capture-MS Homo sapiens
15 ATP5J2-PTCD1  
Proximity Label-MS Homo sapiens
16 EEF1G 1937
Co-fractionation Homo sapiens
17 SLIRP 81892
Proximity Label-MS Homo sapiens
18 NDUFS1 4719
Proximity Label-MS Homo sapiens
19 BCLAF1 9774
Cross-Linking-MS (XL-MS) Homo sapiens
20 PTMA 5757
Affinity Capture-MS Homo sapiens
21 TRMT10C 54931
Proximity Label-MS Homo sapiens
22 TFB2M  
Reconstituted Complex Homo sapiens
23 ANGEL2 90806
Proximity Label-MS Homo sapiens
24 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
25 BTF3 689
Affinity Capture-MS Homo sapiens
26 PDK3 5165
Proximity Label-MS Homo sapiens
27 MRPS10 55173
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 MTPAP 55149
Proximity Label-MS Homo sapiens
29 TRUB2  
Proximity Label-MS Homo sapiens
30 EN1  
Affinity Capture-MS Homo sapiens
31 SOX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 NDUFV3 4731
Proximity Label-MS Homo sapiens
33 KIF20A 10112
Affinity Capture-MS Homo sapiens
34 MRPL10 124995
Proximity Label-MS Homo sapiens
35 KLF12  
Proximity Label-MS Homo sapiens
36 ATP5F1 515
Proximity Label-MS Homo sapiens
37 SSB 6741
Cross-Linking-MS (XL-MS) Homo sapiens
38 SYNE2 23224
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
39 EHMT2 10919
Proximity Label-MS Homo sapiens
40 CAND1 55832
Affinity Capture-MS Homo sapiens
41 C7orf55-LUC7L2  
Proximity Label-MS Homo sapiens
42 PDHB 5162
Co-fractionation Homo sapiens
43 ARL6IP1 23204
Two-hybrid Homo sapiens
44 RRP12 23223
Affinity Capture-MS Homo sapiens
45 MRPL23 6150
Proximity Label-MS Homo sapiens
46 RPS6KB2  
Affinity Capture-MS Homo sapiens
47 SOX10  
Proximity Label-MS Homo sapiens
48 MTRF1  
Proximity Label-MS Homo sapiens
49 MRPS24 64951
Proximity Label-MS Homo sapiens
50 CARS2 79587
Proximity Label-MS Homo sapiens
51 HADH 3033
Proximity Label-MS Homo sapiens
52 MRPS5 64969
Proximity Label-MS Homo sapiens
53 WTAP 9589
Affinity Capture-MS Homo sapiens
54 BAZ2A  
Proximity Label-MS Homo sapiens
55 MRPL12 6182
Proximity Label-MS Homo sapiens
56 NDUFS3 4722
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
57 B3GNT2 10678
Affinity Capture-MS Homo sapiens
58 OGDH 4967
Proximity Label-MS Homo sapiens
59 DLG2 1740
Cross-Linking-MS (XL-MS) Homo sapiens
60 MRPS31  
Proximity Label-MS Homo sapiens
61 PMPCA 23203
Proximity Label-MS Homo sapiens
62 C8orf82  
Proximity Label-MS Homo sapiens
63 NDUFA7 4701
Proximity Label-MS Homo sapiens
64 THEM4  
Proximity Label-MS Homo sapiens
65 HARS2 23438
Proximity Label-MS Homo sapiens
66 MRPS36 92259
Proximity Label-MS Homo sapiens
67 COPS5 10987
Affinity Capture-MS Homo sapiens
68 RPL35 11224
Affinity Capture-MS Homo sapiens
69 PRC1 9055
Affinity Capture-MS Homo sapiens
70 HINT2 84681
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
71 MRPS23 51649
Proximity Label-MS Homo sapiens
72 CUX1 1523
Proximity Label-MS Homo sapiens
73 STATH  
Two-hybrid Homo sapiens
74 CALM3 808
Affinity Capture-MS Homo sapiens
75 E2F4  
Affinity Capture-MS Homo sapiens
76 ETV4  
Proximity Label-MS Homo sapiens
77 BRPF3  
Affinity Capture-MS Homo sapiens
78 WIZ 58525
Proximity Label-MS Homo sapiens
79 LETM1 3954
Proximity Label-MS Homo sapiens
80 DDX58 23586
Affinity Capture-RNA Homo sapiens
81 MRRF  
Proximity Label-MS Homo sapiens
82 TCEA2  
Cross-Linking-MS (XL-MS) Homo sapiens
83 ATP5O 539
Proximity Label-MS Homo sapiens
84 ZNF512B  
Proximity Label-MS Homo sapiens
85 MINOS1  
Co-fractionation Homo sapiens
86 MRPS25 64432
Proximity Label-MS Homo sapiens
87 GOPC 57120
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 LACTB 114294
Co-fractionation Homo sapiens
89 EED  
Affinity Capture-MS Homo sapiens
90 NUSAP1 51203
Affinity Capture-MS Homo sapiens
91 NDUFV1 4723
Proximity Label-MS Homo sapiens
92 ATG16L1 55054
Affinity Capture-MS Homo sapiens
93 TOMM40 10452
Co-fractionation Homo sapiens
94 ETFA 2108
Proximity Label-MS Homo sapiens
95 PYCR1 5831
Proximity Label-MS Homo sapiens
96 MRPS7 51081
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
97 LHX4  
Proximity Label-MS Homo sapiens
98 MECP2 4204
Affinity Capture-MS Homo sapiens
99 TLX3  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 ANKRD34C  
Co-fractionation Homo sapiens
101 MRPL4 51073
Proximity Label-MS Homo sapiens
102 NDUFA6  
Proximity Label-MS Homo sapiens
103 SOX5 6660
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 UQCRQ 27089
Co-fractionation Homo sapiens
105 MRPL47 57129
Proximity Label-MS Homo sapiens
106 ARHGEF4  
Cross-Linking-MS (XL-MS) Homo sapiens
107 MTERF3  
Proximity Label-MS Homo sapiens
108 MRPS9 64965
Proximity Label-MS Homo sapiens
109 KIF14 9928
Affinity Capture-MS Homo sapiens
110 QRSL1  
Proximity Label-MS Homo sapiens
111 PNPT1 87178
Proximity Label-MS Homo sapiens
112 MDH2 4191
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
113 TFB1M  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
114 CHMP4C 92421
Affinity Capture-MS Homo sapiens
115 ALAS1  
Proximity Label-MS Homo sapiens
116 KIFC1 3833
Affinity Capture-MS Homo sapiens
117 GATA4  
Affinity Capture-MS Homo sapiens
118 NDUFA9 4704
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
119 MRPS33  
Proximity Label-MS Homo sapiens
120 C6orf203  
Proximity Label-MS Homo sapiens
121 NDUFS4 4724
Proximity Label-MS Homo sapiens
122 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
123 SOX17  
Proximity Label-MS Homo sapiens
124 MRPL45 84311
Proximity Label-MS Homo sapiens
125 ABCE1 6059
Affinity Capture-MS Homo sapiens
126 SMARCA5 8467
Affinity Capture-MS Homo sapiens
127 MRPS34 65993
Proximity Label-MS Homo sapiens
128 POLG  
Proximity Label-MS Homo sapiens
129 ZBTB24  
Affinity Capture-MS Homo sapiens
130 HSP90B1 7184
Co-fractionation Homo sapiens
131 POLRMT 5442
Proximity Label-MS Homo sapiens
132 MRPS11  
Proximity Label-MS Homo sapiens
133 REXO4  
Affinity Capture-MS Homo sapiens
134 ATPAF1  
Proximity Label-MS Homo sapiens
135 AGTRAP 57085
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
136 PTCD3 55037
Proximity Label-MS Homo sapiens
137 HSCB 150274
Proximity Label-MS Homo sapiens
138 NDUFAF5  
Proximity Label-MS Homo sapiens
139 WDR46  
Affinity Capture-MS Homo sapiens
140 NDUFS8 4728
Proximity Label-MS Homo sapiens
141 MMAB 326625
Proximity Label-MS Homo sapiens
142 MRPS2 51116
Proximity Label-MS Homo sapiens
143 LHX2  
Proximity Label-MS Homo sapiens
144 NDUFAF4 29078
Proximity Label-MS Homo sapiens
145 CEBPZ  
Affinity Capture-MS Homo sapiens
146 ACOT2 10965
Proximity Label-MS Homo sapiens
147 MRPS6  
Proximity Label-MS Homo sapiens
148 ZNF512  
Proximity Label-MS Homo sapiens
149 LHX8  
Proximity Label-MS Homo sapiens
150 POLDIP2 26073
Proximity Label-MS Homo sapiens
151 ECHS1 1892
Proximity Label-MS Homo sapiens
152 SRF  
Affinity Capture-MS Homo sapiens
153 HUWE1 10075
Affinity Capture-MS Homo sapiens
154 CYC1 1537
Co-fractionation Homo sapiens
155 DDX54 79039
Proximity Label-MS Homo sapiens
156 ERAL1  
Proximity Label-MS Homo sapiens
157 HECTD1 25831
Affinity Capture-MS Homo sapiens
158 PDE12 201626
Proximity Label-MS Homo sapiens
159 RNMTL1  
Proximity Label-MS Homo sapiens
160 ATP5H 10476
Proximity Label-MS Homo sapiens
161 BRD4 23476
Affinity Capture-MS Homo sapiens
162 NDUFAF7  
Proximity Label-MS Homo sapiens
163 VDAC2 7417
Co-fractionation Homo sapiens
164 NIPSNAP1 8508
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
165 CYLD  
Affinity Capture-MS Homo sapiens
166 NFATC4 4776
Proximity Label-MS Homo sapiens
167 COX4I1 1327
Co-fractionation Homo sapiens
168 MRPL41 64975
Proximity Label-MS Homo sapiens
169 DDX18 8886
Affinity Capture-MS Homo sapiens
170 MRPL50 54534
Proximity Label-MS Homo sapiens
171 ANLN 54443
Affinity Capture-MS Homo sapiens
172 TEFM  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
173 ZNF644  
Proximity Label-MS Homo sapiens
174 MRPL44  
Proximity Label-MS Homo sapiens
175 GRPEL1 80273
Proximity Label-MS Homo sapiens
176 ACAT1 38
Proximity Label-MS Homo sapiens
177 ZBTB2 57621
Affinity Capture-MS Homo sapiens
178 MRPL40 64976
Proximity Label-MS Homo sapiens
179 EARS2  
Proximity Label-MS Homo sapiens
180 HADHB 3032
Co-fractionation Homo sapiens
181 HADHA 3030
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
182 FANCD2  
Affinity Capture-MS Homo sapiens
183 NKX2-5  
Affinity Capture-MS Homo sapiens
184 CANX 821
Co-fractionation Homo sapiens
185 MTIF2 4528
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
186 MRPL24  
Proximity Label-MS Homo sapiens
187 BAZ1B 9031
Affinity Capture-MS Homo sapiens
188 SOX6  
Affinity Capture-MS Homo sapiens
189 SDHA 6389
Affinity Capture-MS Homo sapiens
190 NDUFAB1 4706
Proximity Label-MS Homo sapiens
191 ECT2 1894
Affinity Capture-MS Homo sapiens
192 NDUFV2 4729
Proximity Label-MS Homo sapiens
193 ELK3  
Proximity Label-MS Homo sapiens
194 MTIF3  
Proximity Label-MS Homo sapiens
195 BEND6  
Cross-Linking-MS (XL-MS) Homo sapiens
196 RTN4IP1  
Proximity Label-MS Homo sapiens
197 CTNNB1 1499
Co-fractionation Homo sapiens
198 ETFB 2109
Proximity Label-MS Homo sapiens
199 DLG1 1739
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
200 MRPS14  
Proximity Label-MS Homo sapiens
201 BRD8 10902
Affinity Capture-MS Homo sapiens
202 NFS1 9054
Proximity Label-MS Homo sapiens
203 C10orf2 56652
Proximity Label-MS Homo sapiens
204 CUL3 8452
Affinity Capture-MS Homo sapiens
205 COL8A2 1296
Two-hybrid Homo sapiens
206 DACH1  
Proximity Label-MS Homo sapiens
207 MRPL42  
Proximity Label-MS Homo sapiens
208 EGFR 1956
Negative Genetic Homo sapiens
209 HSD17B10 3028
Proximity Label-MS Homo sapiens
210 ELAC2 60528
Proximity Label-MS Homo sapiens
211 DHX30 22907
Proximity Label-MS Homo sapiens
212 CDCA2 157313
Cross-Linking-MS (XL-MS) Homo sapiens
213 VARS2  
Proximity Label-MS Homo sapiens
214 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 SUZ12  
Affinity Capture-MS Homo sapiens
216 MRPL37 51253
Proximity Label-MS Homo sapiens
217 FN1 2335
Affinity Capture-MS Homo sapiens
218 C17orf80 55028
Proximity Label-MS Homo sapiens
219 SOX15  
Affinity Capture-MS Homo sapiens
220 ECI2 10455
Proximity Label-MS Homo sapiens
221 C12orf65  
Proximity Label-MS Homo sapiens
222 MYCN  
Affinity Capture-MS Homo sapiens
223 GATB  
Proximity Label-MS Homo sapiens
224 MRPL19 9801
Proximity Label-MS Homo sapiens
225 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
226 KCTD17 79734
Affinity Capture-MS Homo sapiens
227 NDUFA2 4695
Proximity Label-MS Homo sapiens
228 COX6C 1345
Co-fractionation Homo sapiens
229 TACO1  
Proximity Label-MS Homo sapiens
230 FHOD1 29109
Cross-Linking-MS (XL-MS) Homo sapiens
231 SET 6418
Affinity Capture-MS Homo sapiens
232 KIAA0391  
Proximity Label-MS Homo sapiens
233 DLST 1743
Proximity Label-MS Homo sapiens
234 TSFM 10102
Proximity Label-MS Homo sapiens
235 HSDL2 84263
Proximity Label-MS Homo sapiens
236 DAP3 7818
Proximity Label-MS Homo sapiens
237 PPA2 27068
Proximity Label-MS Homo sapiens
238 ATP5B 506
Proximity Label-MS Homo sapiens
239 ACAD9 28976
Proximity Label-MS Homo sapiens
240 RPL7L1 285855
Affinity Capture-MS Homo sapiens
241 PPAN 56342
Affinity Capture-MS Homo sapiens
242 DDRGK1 65992
Affinity Capture-MS Homo sapiens
243 PYCR2 29920
Proximity Label-MS Homo sapiens
244 MAGI3 260425
Cross-Linking-MS (XL-MS) Homo sapiens
245 ATP5C1 509
Cross-Linking-MS (XL-MS) Homo sapiens
246 COX2 4513
Co-fractionation Homo sapiens
247 MRPS17 51373
Proximity Label-MS Homo sapiens
248 ARHGAP23 57636
Affinity Capture-MS Homo sapiens
249 METTL15  
Proximity Label-MS Homo sapiens
250 NFATC2  
Affinity Capture-MS Homo sapiens
251 BRD3 8019
Affinity Capture-MS Homo sapiens
252 LYRM4 57128
Proximity Label-MS Homo sapiens
253 PYHIN1  
Affinity Capture-MS Homo sapiens
254 SPATA13  
Cross-Linking-MS (XL-MS) Homo sapiens
255 VWA8 23078
Proximity Label-MS Homo sapiens
256 NDUFS2 4720
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
257 PPIF 10105
Proximity Label-MS Homo sapiens
258 NDUFA5 4698
Proximity Label-MS Homo sapiens
259 STAT4  
Proximity Label-MS Homo sapiens
260 NDUFAF2  
Proximity Label-MS Homo sapiens
261 AK4 205
Proximity Label-MS Homo sapiens
262 TLX1  
Affinity Capture-MS Homo sapiens
263 CLPP 8192
Proximity Label-MS Homo sapiens
264 DDX50 79009
Proximity Label-MS Homo sapiens
265 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
266 GLS 2744
Proximity Label-MS Homo sapiens
267 EIF3F 8665
Affinity Capture-MS Homo sapiens
268 ATP5J 522
Proximity Label-MS Homo sapiens
269 FBXW11  
Affinity Capture-MS Homo sapiens
270 MAGEF1  
Affinity Capture-MS Homo sapiens
271 AUH 549
Proximity Label-MS Homo sapiens
272 PARP1 142
Affinity Capture-MS Homo sapiens
273 ARID2  
Proximity Label-MS Homo sapiens
274 MRPL22  
Proximity Label-MS Homo sapiens
275 DNAJC19 131118
Proximity Label-MS Homo sapiens
276 FBXL6  
Affinity Capture-MS Homo sapiens
277 HMGB1 3146
Proximity Label-MS Homo sapiens
278 MRPL21 219927
Proximity Label-MS Homo sapiens
279 RRP1B 23076
Affinity Capture-MS Homo sapiens
280 GTPBP6  
Proximity Label-MS Homo sapiens
281 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
282 MRPS28  
Proximity Label-MS Homo sapiens
283 NME4 4833
Proximity Label-MS Homo sapiens
284 DLG3 1741
Cross-Linking-MS (XL-MS) Homo sapiens
285 LRPPRC 10128
Proximity Label-MS Homo sapiens
286 MRPS27 23107
Proximity Label-MS Homo sapiens
287 RPA1 6117
Co-fractionation Homo sapiens
288 KLF3  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 SUPV3L1 6832
Proximity Label-MS Homo sapiens
290 PDHA1 5160
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
291 MRPL28 10573
Proximity Label-MS Homo sapiens
292 SOX4  
Proximity Label-MS Homo sapiens
293 MRPL1  
Proximity Label-MS Homo sapiens
294 NDUFS7 374291
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
295 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
296 COX8A  
Proximity Label-MS Homo sapiens
297 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
298 TSPYL1 7259
Affinity Capture-MS Homo sapiens
299 NDUFA12 55967
Proximity Label-MS Homo sapiens
300 SHMT2 6472
Proximity Label-MS Homo sapiens
301 MRPS18C  
Proximity Label-MS Homo sapiens
302 C21orf33  
Proximity Label-MS Homo sapiens
303 MRPS21  
Proximity Label-MS Homo sapiens
304 KLF16  
Affinity Capture-MS Homo sapiens
305 PPM1G 5496
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 UFL1 23376
Affinity Capture-MS Homo sapiens
307 GUF1  
Proximity Label-MS Homo sapiens
308 KRR1 11103
Affinity Capture-MS Homo sapiens
309 CALM2 805
Affinity Capture-MS Homo sapiens
310 MRPS18B 28973
Proximity Label-MS Homo sapiens
311 RBM28 55131
Affinity Capture-MS Homo sapiens
312 GFM1 85476
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
313 AARS2  
Proximity Label-MS Homo sapiens
314 NEDD1 121441
Affinity Capture-MS Homo sapiens
315 ACOT1 641371
Proximity Label-MS Homo sapiens
316 IBA57  
Proximity Label-MS Homo sapiens
317 MRPL46  
Proximity Label-MS Homo sapiens
318 MGME1  
Proximity Label-MS Homo sapiens
319 MRPL20 55052
Proximity Label-MS Homo sapiens
320 MRPS16  
Proximity Label-MS Homo sapiens
321 GRSF1 2926
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
322 C1QBP 708
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
323 ZUFSP 221302
Affinity Capture-MS Homo sapiens
324 CUL7 9820
Affinity Capture-MS Homo sapiens
325 KRAS 3845
Negative Genetic Homo sapiens
326 COX7C 1350
Co-fractionation Homo sapiens
327 MRPL55  
Proximity Label-MS Homo sapiens
328 MRPL53  
Proximity Label-MS Homo sapiens
329 AMIGO2  
Cross-Linking-MS (XL-MS) Homo sapiens
330 METTL17  
Proximity Label-MS Homo sapiens
331 MRPS22 56945
Proximity Label-MS Homo sapiens
332 SUCLA2 8803
Proximity Label-MS Homo sapiens
333 LEMD3  
Proximity Label-MS Homo sapiens
334 REPIN1  
Affinity Capture-MS Homo sapiens
335 NDUFS6  
Proximity Label-MS Homo sapiens
336 MRPL43 84545
Proximity Label-MS Homo sapiens
337 MGST3 4259
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
338 TIMM44 10469
Proximity Label-MS Homo sapiens
339 ECSIT 51295
Proximity Label-MS Homo sapiens
340 TSPAN1 10103
Two-hybrid Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here