Experiment description of studies that identified PTMA in exosomes

1 Experiment ID 219 ISEV standards ✔ EM EV Biophysical techniques ✘ EV Cytosolic markers ✔ CD63|CD9 EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25857718     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins Authors Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P Journal name Int J Cancer Publication year 2015 Sample Nasopharyngeal carcinoma cells Sample name C666-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.17-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 220 ISEV standards ✔ EM EV Biophysical techniques ✘ EV Cytosolic markers ✔ CD63|CD9 EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25857718     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins Authors Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P Journal name Int J Cancer Publication year 2015 Sample Nasopharyngeal carcinoma cells Sample name NP69 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.17-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 221 ISEV standards ✔ EM EV Biophysical techniques ✘ EV Cytosolic markers ✔ CD63|CD9 EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25857718     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins Authors Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P Journal name Int J Cancer Publication year 2015 Sample Nasopharyngeal carcinoma cells Sample name NP460 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.17-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 217 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101 EV Cytosolic markers ✔ CD81|CD9|CD63 EV Membrane markers ✘ EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for PTMA

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HIST3H3 8290 Invitro Homo sapiens 2 HIST2H2BE 8349 Invitro Homo sapiens 3 PHB2 11331 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 4 NUTF2 10204 Invitro Homo sapiens 5 CCNA2 890 Invitro Homo sapiens 6 SIN3A   Reconstituted Complex Homo sapiens 7 ESR1   Reconstituted Complex Homo sapiens 8 HSPA1A   Affinity Capture-MS Homo sapiens Invitro Homo sapiens 9 NUP62 23636 Invitro Homo sapiens Affinity Capture-MS Homo sapiens 10 KPNB1 3837 Invitro Homo sapiens 11 HIST1H4A 8359 Invitro Homo sapiens 12 KPNA2 3838 Invitro Homo sapiens Affinity Capture-MS Homo sapiens 13 CREBBP   Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 14 CDK1 983 Affinity Capture-MS Homo sapiens Invitro Homo sapiens 15 PCNA 5111 Affinity Capture-MS Homo sapiens Invitro Homo sapiens 16 HDAC1 3065 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 17 CDK2 1017 Affinity Capture-MS Homo sapiens Invitro Homo sapiens 18 CCNB1 891 Invitro Homo sapiens 19 NCOR1   Reconstituted Complex Homo sapiens 20 RAN 5901 Invitro Homo sapiens Affinity Capture-MS Homo sapiens 21 SET 6418 Affinity Capture-MS Homo sapiens 22 HDAC2 3066 Reconstituted Complex Homo sapiens 23 RCC1 1104 Invitro Homo sapiens Affinity Capture-MS Homo sapiens 24 EP300 2033 Reconstituted Complex Homo sapiens Phenotypic Enhancement Homo sapiens 25 CDK4 1019 Affinity Capture-MS Homo sapiens Invitro Homo sapiens View the network

Pathways in which PTMA is involved

No pathways found