Gene description for CDK1
Gene name	cyclin-dependent kinase 1
Gene symbol	CDK1
Other names/aliases	CDC2 CDC28A P34CDC2
Species	Homo sapiens
Database cross references - CDK1
ExoCarta	ExoCarta_983
Entrez Gene	983
HGNC	1722
MIM	116940
UniProt	P06493
CDK1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Squamous carcinoma cells	20124223
Thymus	23844026
Urine	19056867

Gene ontology annotations for CDK1

Molecular Function     protein kinase activity GO:0004672 IDA     protein serine/threonine kinase activity GO:0004674 IDA     RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 IDA     cyclin-dependent protein serine/threonine kinase activity GO:0004693 TAS     Hsp70 protein binding GO:0030544 IEA     ATP binding GO:0005524 IEA     cyclin binding GO:0030332 IEA     histone kinase activity GO:0035173 IEA     protein binding GO:0005515 IPI Biological Process     innate immune response GO:0045087 TAS     mitotic nuclear division GO:0007067 IEA     protein localization to kinetochore GO:0034501 IDA     positive regulation of protein import into nucleus, translocation GO:0033160 IEA     peptidyl-threonine phosphorylation GO:0018107 IDA     response to activity GO:0014823 IEA     regulation of embryonic development GO:0045995 TAS     DNA replication GO:0006260 TAS     positive regulation of DNA replication GO:0045740 IEA     toll-like receptor 4 signaling pathway GO:0034142 TAS     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     mitotic nuclear envelope disassembly GO:0007077 TAS     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     positive regulation of gene expression GO:0010628 IEA     G1/S transition of mitotic cell cycle GO:0000082 TAS     ventricular cardiac muscle cell development GO:0055015 IEA     activation of MAPK activity GO:0000187 TAS     toll-like receptor 10 signaling pathway GO:0034166 TAS     response to axon injury GO:0048678 IEA     epithelial cell differentiation GO:0030855 IEP     insulin receptor signaling pathway GO:0008286 TAS     response to cadmium ion GO:0046686 IEA     response to ethanol GO:0045471 IEA     regulation of Schwann cell differentiation GO:0014038 TAS     response to toxic substance GO:0009636 IEA     pronuclear fusion GO:0007344 TAS     mitotic G2 DNA damage checkpoint GO:0007095 IEA     organelle organization GO:0006996 TAS     chromosome condensation GO:0030261 IEA     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     mitotic cell cycle GO:0000278 TAS     histone phosphorylation GO:0016572 IEA     apoptotic process GO:0006915 IEA     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     organ regeneration GO:0031100 IEA     protein complex assembly GO:0006461 IEA     response to copper ion GO:0046688 IEA     regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 TAS     toll-like receptor 9 signaling pathway GO:0034162 TAS     response to amine GO:0014075 IEA     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     negative regulation of apoptotic process GO:0043066 IDA     response to organic cyclic compound GO:0014070 IEA     cell migration GO:0016477 TAS     stress-activated MAPK cascade GO:0051403 TAS     axon guidance GO:0007411 TAS     toll-like receptor 3 signaling pathway GO:0034138 TAS     toll-like receptor 2 signaling pathway GO:0034134 TAS     peptidyl-serine phosphorylation GO:0018105 IDA     positive regulation of mitotic cell cycle GO:0045931 IEA     small GTPase mediated signal transduction GO:0007264 TAS     toll-like receptor signaling pathway GO:0002224 TAS     positive regulation of cardiac muscle cell proliferation GO:0060045 IEA     G2/M transition of mitotic cell cycle GO:0000086 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     microtubule cytoskeleton organization GO:0000226 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     cell aging GO:0007569 IEA     anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 TAS     Ras protein signal transduction GO:0007265 TAS     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     activation of MAPKK activity GO:0000186 TAS     cell division GO:0051301 IEA     MAPK cascade GO:0000165 TAS     toll-like receptor 5 signaling pathway GO:0034146 TAS     centrosome cycle GO:0007098 TAS     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083 TAS     response to drug GO:0042493 IEA     DNA repair GO:0006281 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     cellular response to hydrogen peroxide GO:0070301 IEA     positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition GO:0051437 TAS Subcellular Localization     nucleus GO:0005634 IDA     extracellular exosome GO:0070062 IDA     mitochondrion GO:0005739 TAS     centrosome GO:0005813 IDA     nucleoplasm GO:0005654 TAS     mitotic spindle GO:0072686 IDA     midbody GO:0030496 IDA     spindle microtubule GO:0005876 IDA     cytosol GO:0005829 TAS     membrane GO:0016020 IDA     cytoplasm GO:0005737 IDA