Gene description for MOB2
Gene name MOB kinase activator 2
Gene symbol MOB2
Other names/aliases HCCA2
Species Homo sapiens
 Database cross references - MOB2
ExoCarta ExoCarta_81532
Entrez Gene 81532
HGNC 24904
MIM 611969
UniProt Q70IA6  
 MOB2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for MOB2
Molecular Function
    metal ion binding GO:0046872 IEA
Biological Process
    actin cytoskeleton organization GO:0030036 IEA
    positive regulation of protein phosphorylation GO:0001934 IEA
    positive regulation of neuron projection development GO:0010976 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
    cytoplasm GO:0005737 IDA
    neuron projection terminus GO:0044306 IEA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified MOB2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MOB2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MOB2 is involved
No pathways found





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