Gene description for MYH9
Gene name myosin, heavy chain 9, non-muscle
Gene symbol MYH9
Other names/aliases BDPLT6
DFNA17
EPSTS
FTNS
MHA
NMHC-II-A
NMMHC-IIA
NMMHCA
Species Homo sapiens
 Database cross references - MYH9
ExoCarta ExoCarta_4627
Vesiclepedia VP_4627
Entrez Gene 4627
HGNC 7579
MIM 160775
UniProt P35579  
 MYH9 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Mesothelioma cells 15111327    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Plasma 19028452    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Saliva 19199708    
T lymphocytes 34108659    
Thymus 23844026    
Urine 15326289    
Urine 19056867    
 Gene ontology annotations for MYH9
Molecular Function
    microfilament motor activity GO:0000146 IDA
    microfilament motor activity GO:0000146 IDA
    virus receptor activity GO:0001618 IDA
    RNA binding GO:0003723 HDA
    cytoskeletal motor activity GO:0003774 NAS
    actin binding GO:0003779 IDA
    integrin binding GO:0005178 IDA
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 IEA
    ATP binding GO:0005524 IDA
    protein domain specific binding GO:0019904 IPI
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IDA
    protein-membrane adaptor activity GO:0043495 IMP
    ADP binding GO:0043531 IDA
    cadherin binding GO:0045296 HDA
    actin filament binding GO:0051015 IDA
    actin filament binding GO:0051015 IDA
    actin filament binding GO:0051015 NAS
Biological Process
    meiotic spindle organization GO:0000212 IEA
    angiogenesis GO:0001525 IDA
    in utero embryonic development GO:0001701 IEA
    establishment of T cell polarity GO:0001768 IEA
    plasma membrane repair GO:0001778 IDA
    membrane protein ectodomain proteolysis GO:0006509 IDA
    phagocytosis, engulfment GO:0006911 ISS
    integrin-mediated signaling pathway GO:0007229 NAS
    myoblast fusion GO:0007520 IEA
    regulation of cell shape GO:0008360 IMP
    protein transport GO:0015031 IMP
    actin cytoskeleton organization GO:0030036 IMP
    actin filament-based movement GO:0030048 IDA
    actin filament-based movement GO:0030048 IDA
    platelet formation GO:0030220 IMP
    monocyte differentiation GO:0030224 IEP
    actomyosin structure organization GO:0031032 IDA
    lysosome localization GO:0032418 IMP
    cytokinetic process GO:0032506 IMP
    uropod organization GO:0032796 IEA
    endodermal cell differentiation GO:0035987 IEA
    blood vessel endothelial cell migration GO:0043534 IMP
    regulated exocytosis GO:0045055 IMP
    symbiont entry into host cell GO:0046718 IDA
    leukocyte migration GO:0050900 NAS
    establishment of meiotic spindle localization GO:0051295 IEA
    cortical granule exocytosis GO:0060471 ISS
    platelet aggregation GO:0070527 HMP
    negative regulation of actin filament severing GO:1903919 IMP
    negative regulation of actin filament severing GO:1903919 ISS
    positive regulation of protein processing in phagocytic vesicle GO:1903923 ISS
    regulation of plasma membrane repair GO:1905684 IMP
Subcellular Localization
    stress fiber GO:0001725 IDA
    ruffle GO:0001726 IDA
    immunological synapse GO:0001772 IDA
    uropod GO:0001931 IDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    spindle GO:0005819 IEA
    actomyosin contractile ring GO:0005826 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    brush border GO:0005903 IEA
    adherens junction GO:0005912 IEA
    focal adhesion GO:0005925 ISS
    COP9 signalosome GO:0008180 IDA
    cytoplasmic side of plasma membrane GO:0009898 IDA
    cell surface GO:0009986 IDA
    actin cytoskeleton GO:0015629 IDA
    membrane GO:0016020 HDA
    myosin II complex GO:0016460 IBA
    myosin II complex GO:0016460 IDA
    nuclear body GO:0016604 IDA
    cell leading edge GO:0031252 IDA
    neuromuscular junction GO:0031594 IEA
    cleavage furrow GO:0032154 IDA
    myosin filament GO:0032982 IBA
    protein-containing complex GO:0032991 IDA
    actomyosin GO:0042641 IDA
    cortical granule GO:0060473 ISS
    extracellular exosome GO:0070062 HDA
    myosin II filament GO:0097513 IDA
 Experiment description of studies that identified MYH9 in sEVs
1
Experiment ID 79
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
EM
Biophysical techniques
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1333
MISEV standards
Biophysical techniques
CD81|EPCAM|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
18
Experiment ID 1334
MISEV standards
Biophysical techniques
CD9
Enriched markers
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
19
Experiment ID 1334
MISEV standards
Biophysical techniques
CD9
Enriched markers
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
20
Experiment ID 1334
MISEV standards
Biophysical techniques
CD9
Enriched markers
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
21
Experiment ID 1335
MISEV standards
Biophysical techniques
EPCAM|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
22
Experiment ID 1336
MISEV standards
Biophysical techniques
CD9
Enriched markers
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
23
Experiment ID 1336
MISEV standards
Biophysical techniques
CD9
Enriched markers
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
24
Experiment ID 1336
MISEV standards
Biophysical techniques
CD9
Enriched markers
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
25
Experiment ID 494
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 496
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
27
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
28
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
29
Experiment ID 20
MISEV standards
EM
Biophysical techniques
HSP90|CD63|CD81|LAMP1
Enriched markers
GOLGA2|cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
30
Experiment ID 21
MISEV standards
EM|IEM
Biophysical techniques
Alix|TSG101|HSP70|CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
31
Experiment ID 201
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 282
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
33
Experiment ID 283
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
34
Experiment ID 285
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
35
Experiment ID 286
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
36
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
37
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
43
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 200
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
50
Experiment ID 254
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
51
Experiment ID 255
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
52
Experiment ID 256
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
53
Experiment ID 257
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
54
Experiment ID 258
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
55
Experiment ID 259
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 260
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
57
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
58
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
59
Experiment ID 25
MISEV standards
IEM
Biophysical techniques
HSP90|beta-tubulin
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15111327    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes secreted by human mesothelioma cells.
Authors "Hegmans JP, Bard MP, Hemmes A, Luider TM, Kleijmeer MJ, Prins JB, Zitvogel L, Burgers SA, Hoogsteden HC, Lambrecht BN."
Journal name AJP
Publication year 2004
Sample Mesothelioma cells
Sample name PMR-MM7
PMR-MM8
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
60
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
61
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
62
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
63
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
64
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
65
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
66
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
67
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
68
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
69
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
70
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
71
Experiment ID 44
MISEV standards
IEM
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19028452    
Organism Homo sapiens
Experiment description Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
Authors "Looze C, Yui D, Leung L, Ingham M, Kaler M, Yao X, Wu WW, Shen RF, Daniels MP, Levine SJ"
Journal name BBRC
Publication year 2009
Sample Plasma
Sample name Plasma
Isolation/purification methods Filtration
Size exclusion
Sucrose density gradient
Flotation density 1.15-1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
72
Experiment ID 231
MISEV standards
Biophysical techniques
Alix|CD63|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
73
Experiment ID 232
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
74
Experiment ID 233
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
75
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
76
Experiment ID 138
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
77
Experiment ID 139
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
78
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
79
Experiment ID 274
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
80
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
81
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
82
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
83
Experiment ID 13
MISEV standards
IEM
Biophysical techniques
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
84
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for MYH9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Co-fractionation Homo sapiens
2 MUC13 56667
Affinity Capture-MS Homo sapiens
3 ISG15 9636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 WDR6 11180
Co-fractionation Homo sapiens
5 PPP2R4 5524
Affinity Capture-MS Homo sapiens
6 HDAC2 3066
Co-fractionation Homo sapiens
7 RBPMS 11030
Affinity Capture-MS Homo sapiens
8 SHC1 6464
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 EIF3C 8663
Co-fractionation Homo sapiens
10 ATG9A 79065
Affinity Capture-Western Homo sapiens
11 ARPC2 10109
Affinity Capture-MS Homo sapiens
12 DYNC1I2 1781
Co-fractionation Homo sapiens
13 TPM2 7169
Affinity Capture-MS Homo sapiens
14 ARPC4 10093
Affinity Capture-MS Homo sapiens
15 ACTC1 70
Affinity Capture-MS Homo sapiens
16 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
17 UBE3A 7337
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
18 UBC 7316
Affinity Capture-Western Homo sapiens
19 KPNA2 3838
Co-fractionation Homo sapiens
20 SMARCC1 6599
Co-fractionation Homo sapiens
21 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
22 CFL2 1073
Affinity Capture-MS Homo sapiens
23 OTUD3 23252
Affinity Capture-MS Homo sapiens
24 APEX1 328
Affinity Capture-MS Homo sapiens
25 WDR76  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 PPP1CB 5500
Affinity Capture-MS Homo sapiens
27 KIF23 9493
Affinity Capture-MS Homo sapiens
28 CTDSPL2  
Cross-Linking-MS (XL-MS) Homo sapiens
29 ACTR3 10096
Affinity Capture-MS Homo sapiens
30 AP2A1 160
Affinity Capture-MS Homo sapiens
31 TRIOBP 11078
Affinity Capture-MS Homo sapiens
32 RAI14 26064
Affinity Capture-MS Homo sapiens
33 SEL1L 6400
Co-fractionation Homo sapiens
34 CALD1 800
Affinity Capture-MS Homo sapiens
35 HSPH1 10808
Co-fractionation Homo sapiens
36 PSMB6 5694
Co-fractionation Homo sapiens
37 PIK3C3 5289
Affinity Capture-MS Homo sapiens
38 NCOA3  
Affinity Capture-MS Homo sapiens
39 GSPT1 2935
Co-fractionation Homo sapiens
40 DYNLL1 8655
Co-fractionation Homo sapiens
41 GTSE1 51512
Affinity Capture-MS Homo sapiens
42 MECP2 4204
Affinity Capture-MS Homo sapiens
43 NSFL1C 55968
Affinity Capture-MS Homo sapiens
44 PPP6R3 55291
Co-fractionation Homo sapiens
45 GPS1 2873
Co-fractionation Homo sapiens
46 WDR5 11091
Co-fractionation Homo sapiens
47 MTA2 9219
Co-fractionation Homo sapiens
48 KIF14 9928
Affinity Capture-MS Homo sapiens
49 CCDC102A 92922
Affinity Capture-MS Homo sapiens
50 EMC9  
Affinity Capture-MS Homo sapiens
51 UNC45A 55898
Affinity Capture-MS Homo sapiens
52 CAPZA1 829
Affinity Capture-MS Homo sapiens
53 USP11 8237
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
54 SORBS2  
Affinity Capture-MS Homo sapiens
55 LUZP1 7798
Affinity Capture-MS Homo sapiens
56 PTP4A3  
Affinity Capture-MS Homo sapiens
57 UBASH3B 84959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 CDH1 999
Proximity Label-MS Homo sapiens
59 FYN 2534
Affinity Capture-MS Homo sapiens
60 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 ACTN4 81
Affinity Capture-MS Homo sapiens
62 RPL31 6160
Cross-Linking-MS (XL-MS) Homo sapiens
63 ARHGAP11A  
Affinity Capture-MS Homo sapiens
64 ACADM 34
Affinity Capture-MS Homo sapiens
65 ASCC2 84164
Two-hybrid Homo sapiens
66 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
67 MRPS18C  
Affinity Capture-MS Homo sapiens
68 FNBP1 23048
Co-fractionation Homo sapiens
69 ITGB2 3689
Affinity Capture-Western Homo sapiens
70 PICALM 8301
Affinity Capture-MS Homo sapiens
71 ST5 6764
Affinity Capture-MS Homo sapiens
72 DSN1 79980
Affinity Capture-MS Homo sapiens
73 PPP1R12B 4660
Affinity Capture-MS Homo sapiens
74 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 DST 667
Affinity Capture-MS Homo sapiens
76 TMPO 7112
Affinity Capture-MS Homo sapiens
77 MYL3 4634
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 NASP 4678
Co-fractionation Homo sapiens
79 AHDC1  
Affinity Capture-MS Homo sapiens
80 AHCYL1 10768
Co-fractionation Homo sapiens
81 NDUFA13 51079
Cross-Linking-MS (XL-MS) Homo sapiens
82 KIF20A 10112
Affinity Capture-MS Homo sapiens
83 SIRT7  
Affinity Capture-MS Homo sapiens
84 LMO7 4008
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
85 IQCB1  
Affinity Capture-MS Homo sapiens
86 MYH14 79784
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
87 ANXA1 301
Protein-peptide Homo sapiens
88 BCAP31 10134
Affinity Capture-MS Homo sapiens
89 CUL3 8452
Affinity Capture-MS Homo sapiens
90 YWHAZ 7534
Two-hybrid Homo sapiens
91 Trim59  
Affinity Capture-MS Mus musculus
92 MYO19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 USP47 55031
Co-fractionation Homo sapiens
94 DIXDC1  
Affinity Capture-MS Homo sapiens
95 FN1 2335
Affinity Capture-MS Homo sapiens
96 BLK 640
Affinity Capture-MS Homo sapiens
97 TUBA4A 7277
Co-fractionation Homo sapiens
98 PRMT5 10419
Co-fractionation Homo sapiens
99 GNAS 2778
Affinity Capture-MS Homo sapiens
100 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
101 HSPA1A 3303
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
102 PSMC5 5705
Co-fractionation Homo sapiens
103 NDUFA3  
Affinity Capture-MS Homo sapiens
104 TPM4 7171
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
105 STUB1 10273
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
106 ARPC3 10094
Affinity Capture-MS Homo sapiens
107 GRK5 2869
Affinity Capture-MS Homo sapiens
108 TNRC18  
Cross-Linking-MS (XL-MS) Homo sapiens
109 DAB2 1601
Affinity Capture-MS Homo sapiens
110 GRB2 2885
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
111 SIK2  
Affinity Capture-MS Homo sapiens
112 SSFA2 6744
Affinity Capture-MS Homo sapiens
113 PLEC 5339
Affinity Capture-MS Homo sapiens
114 MACF1 23499
Affinity Capture-MS Homo sapiens
115 USP1 7398
Affinity Capture-MS Homo sapiens
116 RUVBL2 10856
Co-fractionation Homo sapiens
117 MISP 126353
Affinity Capture-MS Homo sapiens
118 LAMP5  
Cross-Linking-MS (XL-MS) Homo sapiens
119 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
120 PPP1R9B 84687
Affinity Capture-MS Homo sapiens
121 ITPR3 3710
Affinity Capture-MS Homo sapiens
122 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
123 STK38L 23012
Affinity Capture-MS Homo sapiens
124 OS9 10956
Affinity Capture-MS Homo sapiens
125 PSMA1 5682
Co-fractionation Homo sapiens
126 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
127 EIF4B 1975
Co-fractionation Homo sapiens
128 DAPK3 1613
Affinity Capture-MS Homo sapiens
129 CLTA 1211
Affinity Capture-MS Homo sapiens
130 GAGE5  
Affinity Capture-MS Homo sapiens
131 PSMB7 5695
Co-fractionation Homo sapiens
132 LDLR 3949
Negative Genetic Homo sapiens
133 PRPF4 9128
Co-fractionation Homo sapiens
134 SNW1 22938
Affinity Capture-MS Homo sapiens
135 ADRM1 11047
Co-fractionation Homo sapiens
136 ANXA2 302
Affinity Capture-MS Homo sapiens
137 PSMC4 5704
Co-fractionation Homo sapiens
138 PSMD3 5709
Co-fractionation Homo sapiens
139 ABLIM1 3983
Affinity Capture-MS Homo sapiens
140 HSPA6 3310
Co-fractionation Homo sapiens
141 CPM 1368
Affinity Capture-MS Homo sapiens
142 PAWR 5074
Affinity Capture-MS Homo sapiens
143 TARDBP 23435
Affinity Capture-MS Homo sapiens
144 RPA2 6118
Affinity Capture-MS Homo sapiens
145 VPRBP 9730
Co-fractionation Homo sapiens
146 ALB 213
Cross-Linking-MS (XL-MS) Homo sapiens
147 GNS 2799
Co-fractionation Homo sapiens
148 LGALS1 3956
Affinity Capture-MS Homo sapiens
149 HSP90AB1 3326
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
150 SYVN1 84447
Affinity Capture-MS Homo sapiens
151 CLTB 1212
Affinity Capture-MS Homo sapiens
152 ATP5L 10632
Co-fractionation Homo sapiens
153 KIF13B 23303
Affinity Capture-MS Homo sapiens
154 S100A4 6275
Affinity Capture-MS Homo sapiens
155 C9orf156  
Affinity Capture-MS Homo sapiens
156 CORO1B 57175
Affinity Capture-MS Homo sapiens
157 MYO5B 4645
Affinity Capture-MS Homo sapiens
158 COPS6 10980
Co-fractionation Homo sapiens
159 NCKIPSD 51517
Co-fractionation Homo sapiens
160 PRC1 9055
Affinity Capture-MS Homo sapiens
161 ACTR1A 10121
Co-fractionation Homo sapiens
162 PLCG1 5335
Co-fractionation Homo sapiens
163 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
164 OTUD6B 51633
Co-fractionation Homo sapiens
165 TPRN 286262
Affinity Capture-MS Homo sapiens
166 VCAM1 7412
Affinity Capture-MS Homo sapiens
167 PALLD 23022
Affinity Capture-MS Homo sapiens
168 CUL1 8454
Affinity Capture-MS Homo sapiens
169 PMPCB 9512
Affinity Capture-MS Homo sapiens
170 OAT 4942
Affinity Capture-MS Homo sapiens
171 USP7 7874
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
172 TWF1 5756
Affinity Capture-MS Homo sapiens
173 GCA 25801
Affinity Capture-MS Homo sapiens
174 PES1 23481
Affinity Capture-MS Homo sapiens
175 SMC2 10592
Co-fractionation Homo sapiens
176 MYL9 10398
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
177 NNT 23530
Affinity Capture-MS Homo sapiens
178 ACTA2 59
Co-fractionation Homo sapiens
179 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
180 RBX1 9978
Affinity Capture-MS Homo sapiens
181 KLC1 3831
Co-fractionation Homo sapiens
182 AMFR 267
Affinity Capture-MS Homo sapiens
183 STOM 2040
Affinity Capture-MS Homo sapiens
184 COBL  
Affinity Capture-MS Homo sapiens
185 GNAI1 2770
Affinity Capture-MS Homo sapiens
186 LYN 4067
Affinity Capture-MS Homo sapiens
187 Samm50  
Affinity Capture-MS Mus musculus
188 CBL 867
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
189 EFHD2 79180
Affinity Capture-MS Homo sapiens
190 PNMA3  
Affinity Capture-MS Homo sapiens
191 APOB 338
Affinity Capture-MS Homo sapiens
192 PPP2CA 5515
Two-hybrid Homo sapiens
193 LUC7L2 51631
Co-fractionation Homo sapiens
194 MBD2 8932
Co-fractionation Homo sapiens
195 MAGOH 4116
Affinity Capture-MS Homo sapiens
196 TRIM72  
Affinity Capture-Western Homo sapiens
197 COPS7B 64708
Co-fractionation Homo sapiens
198 PRKCE 5581
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
199 STON2 85439
Affinity Capture-MS Homo sapiens
200 PSMA3 5684
Affinity Capture-MS Homo sapiens
201 COPS7A 50813
Co-fractionation Homo sapiens
202 ARPC1B 10095
Affinity Capture-MS Homo sapiens
203 USP15 9958
Co-fractionation Homo sapiens
204 RAB11A 8766
Co-fractionation Homo sapiens
205 PRKAR2A 5576
Co-fractionation Homo sapiens
206 MEX3A  
Affinity Capture-RNA Homo sapiens
207 SRSF5 6430
Co-fractionation Homo sapiens
208 EGFR 1956
Affinity Capture-Western Homo sapiens
209 GAS2L3  
Affinity Capture-MS Homo sapiens
210 PACSIN3 29763
Affinity Capture-MS Homo sapiens
211 ENKUR  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
212 SORD 6652
Affinity Capture-MS Homo sapiens
213 SPTBN1 6711
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
214 ELMSAN1  
Affinity Capture-MS Homo sapiens
215 KDM3B  
Affinity Capture-MS Homo sapiens
216 CDK2 1017
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 CEP250 11190
Affinity Capture-MS Homo sapiens
218 TPM1 7168
Affinity Capture-MS Homo sapiens
219 CORO2A  
Affinity Capture-MS Homo sapiens
220 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
221 BAG1 573
Affinity Capture-MS Homo sapiens
222 TMOD3 29766
Affinity Capture-MS Homo sapiens
223 JMY  
Affinity Capture-MS Homo sapiens
224 DSTN 11034
Affinity Capture-MS Homo sapiens
225 HIP1 3092
Affinity Capture-MS Homo sapiens
226 DPM2 8818
Affinity Capture-MS Homo sapiens
227 DDRGK1 65992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 Yap1  
Reconstituted Complex Mus musculus
229 AKAP2 11217
Affinity Capture-MS Homo sapiens
230 CEP83  
Affinity Capture-MS Homo sapiens
231 MPRIP 23164
Affinity Capture-MS Homo sapiens
232 PSMD7 5713
Co-fractionation Homo sapiens
233 CYFIP1 23191
Co-fractionation Homo sapiens
234 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 PPIF 10105
Affinity Capture-MS Homo sapiens
236 STX12 23673
Affinity Capture-MS Homo sapiens
237 PSMB10 5699
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 TERF2  
Affinity Capture-MS Homo sapiens
239 MYL6 4637
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
240 H3F3A 3020
Co-fractionation Homo sapiens
241 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
242 FOLR1 2348
Affinity Capture-MS Homo sapiens
243 SIPA1 6494
Affinity Capture-MS Homo sapiens
244 PPP2R2A 5520
Co-fractionation Homo sapiens
245 PRKCI 5584
Co-fractionation Homo sapiens
246 Myo1c 17913
Affinity Capture-MS Mus musculus
247 SIPA1L3  
Affinity Capture-MS Homo sapiens
248 CAPZA2 830
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 MDH2 4191
Affinity Capture-MS Homo sapiens
250 CAPRIN1 4076
Co-fractionation Homo sapiens
251 ACTRT1  
Affinity Capture-MS Homo sapiens
252 LSS 4047
Affinity Capture-MS Homo sapiens
253 Myh10 77579
Affinity Capture-MS Mus musculus
254 ESR1  
Affinity Capture-MS Homo sapiens
255 NCAPD2 9918
Co-fractionation Homo sapiens
256 EEF1D 1936
Affinity Capture-MS Homo sapiens
257 GAPVD1 26130
Co-fractionation Homo sapiens
258 TRIB3  
Affinity Capture-MS Homo sapiens
259 C1QBP 708
Affinity Capture-MS Homo sapiens
260 KRAS 3845
Affinity Capture-MS Homo sapiens
261 PPP2R1A 5518
Co-fractionation Homo sapiens
262 SSH2  
Affinity Capture-MS Homo sapiens
263 PRMT1 3276
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
264 RCOR1  
Co-fractionation Homo sapiens
265 MYL12B 103910
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 HBZ  
Affinity Capture-MS Homo sapiens
267 DNAH6 1768
Cross-Linking-MS (XL-MS) Homo sapiens
268 MME 4311
Affinity Capture-MS Homo sapiens
269 LIMCH1 22998
Affinity Capture-MS Homo sapiens
270 EPS15 2060
Affinity Capture-MS Homo sapiens
271 SSB 6741
Co-fractionation Homo sapiens
272 MYO5C 55930
Affinity Capture-MS Homo sapiens
273 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
274 HNRNPUL2 221092
Co-fractionation Homo sapiens
275 LRPPRC 10128
Co-fractionation Homo sapiens
276 CAPZB 832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
277 GNG12 55970
Affinity Capture-MS Homo sapiens
278 RUVBL1 8607
Co-fractionation Homo sapiens
279 MCM2 4171
Affinity Capture-MS Homo sapiens
280 SPAG9 9043
Co-fractionation Homo sapiens
281 IQGAP1 8826
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
282 TRIM56 81844
Affinity Capture-MS Homo sapiens
283 PSMC2 5701
Co-fractionation Homo sapiens
284 RALA 5898
Co-fractionation Homo sapiens
285 ITGA4 3676
Affinity Capture-MS Homo sapiens
286 GOLGA4  
Co-fractionation Homo sapiens
287 ATG9B  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
288 ARHGEF17 9828
Affinity Capture-MS Homo sapiens
289 TFCP2 7024
Affinity Capture-MS Homo sapiens
290 CYLD  
Affinity Capture-MS Homo sapiens
291 NDUFS5 4725
Affinity Capture-MS Homo sapiens
292 CYBRD1 79901
Affinity Capture-MS Homo sapiens
293 HSPA8 3312
Co-fractionation Homo sapiens
294 PSME3 10197
Co-fractionation Homo sapiens
295 MYO18A 399687
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 ATP5A1 498
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
297 EML4 27436
Co-fractionation Homo sapiens
298 ANTXR1 84168
Affinity Capture-MS Homo sapiens
299 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 TCEA2  
Affinity Capture-MS Homo sapiens
301 ACACA 31
Co-fractionation Homo sapiens
302 MKRN2 23609
Affinity Capture-MS Homo sapiens
303 CHMP4B 128866
Affinity Capture-MS Homo sapiens
304 BTF3 689
Affinity Capture-MS Homo sapiens
305 MSN 4478
Affinity Capture-MS Homo sapiens
306 NTRK1 4914
Affinity Capture-MS Homo sapiens
307 U2AF2 11338
Co-fractionation Homo sapiens
308 DNAJA1 3301
Co-fractionation Homo sapiens
309 FLNB 2317
Affinity Capture-MS Homo sapiens
310 ACTB 60
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
311 TUBA1B 10376
Co-fractionation Homo sapiens
312 COPS3 8533
Co-fractionation Homo sapiens
313 GNAI2 2771
Affinity Capture-MS Homo sapiens
314 LRRFIP1 9208
Co-fractionation Homo sapiens
315 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
316 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
317 PSMD2 5708
Co-fractionation Homo sapiens
318 MYL12A 10627
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
319 DBN1 1627
Affinity Capture-MS Homo sapiens
320 BZW1 9689
Co-fractionation Homo sapiens
321 GPRC5A 9052
Affinity Capture-MS Homo sapiens
322 SP1  
Affinity Capture-MS Homo sapiens
323 AKAP10 11216
Co-fractionation Homo sapiens
324 ITPR2 3709
Affinity Capture-MS Homo sapiens
325 METTL14  
Affinity Capture-MS Homo sapiens
326 SHROOM3 57619
Affinity Capture-MS Homo sapiens
327 ECT2 1894
Affinity Capture-MS Homo sapiens
328 TRAF3IP1 26146
Affinity Capture-MS Homo sapiens
329 AHNAK 79026
Affinity Capture-MS Homo sapiens
330 ARFGEF1 10565
Co-fractionation Homo sapiens
331 PSMD6 9861
Co-fractionation Homo sapiens
332 TRAF6 7189
Affinity Capture-Western Homo sapiens
333 MYO5A 4644
Affinity Capture-MS Homo sapiens
334 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
335 NEXN 91624
Affinity Capture-MS Homo sapiens
336 CORO1C 23603
Affinity Capture-MS Homo sapiens
337 BASP1 10409
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
338 AP2M1 1173
Affinity Capture-MS Homo sapiens
339 CCDC50 152137
Affinity Capture-MS Homo sapiens
340 GIGYF2 26058
Co-fractionation Homo sapiens
341 NRBP1 29959
Co-fractionation Homo sapiens
342 NCAPH 23397
Affinity Capture-MS Homo sapiens
343 SYNPO 11346
Affinity Capture-MS Homo sapiens
344 GNB2 2783
Affinity Capture-MS Homo sapiens
345 SEC16A 9919
Affinity Capture-MS Homo sapiens
346 RPS14 6208
Co-fractionation Homo sapiens
347 EPB41 2035
Affinity Capture-MS Homo sapiens
348 RPL22 6146
Affinity Capture-MS Homo sapiens
349 FLII 2314
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
350 SEPT7 989
Co-fractionation Homo sapiens
351 HSPD1 3329
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
352 HSPA9 3313
Co-fractionation Homo sapiens
353 TSR1 55720
Co-fractionation Homo sapiens
354 ZNF787  
Co-fractionation Homo sapiens
355 FLOT1 10211
Affinity Capture-MS Homo sapiens
356 NCAPG 64151
Co-fractionation Homo sapiens
357 TPM3 7170
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
358 IMMT 10989
Affinity Capture-MS Homo sapiens
359 PIP5K1A 8394
Affinity Capture-MS Homo sapiens
360 MTHFD2 10797
Affinity Capture-MS Homo sapiens
361 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
362 PLS1 5357
Affinity Capture-MS Homo sapiens
363 JUP 3728
Affinity Capture-MS Homo sapiens
364 SPTBN2 6712
Affinity Capture-MS Homo sapiens
365 Fcho2  
Affinity Capture-MS Mus musculus
366 MCM5 4174
Affinity Capture-MS Homo sapiens
367 PPP1CC 5501
Affinity Capture-MS Homo sapiens
368 RPA1 6117
Affinity Capture-MS Homo sapiens
369 MEN1 4221
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
370 ALDH1B1 219
Affinity Capture-MS Homo sapiens
371 CREBBP  
Affinity Capture-MS Homo sapiens
372 HDAC5 10014
Affinity Capture-MS Homo sapiens
373 OARD1 221443
Affinity Capture-MS Homo sapiens
374 TRAP1 10131
Affinity Capture-MS Homo sapiens
375 PDZD8 118987
Affinity Capture-MS Homo sapiens
376 UFL1 23376
Affinity Capture-MS Homo sapiens
377 ACTG1 71
Affinity Capture-MS Homo sapiens
378 ACTA1 58
Affinity Capture-MS Homo sapiens
379 MRPS18B 28973
Co-fractionation Homo sapiens
380 AFAP1 60312
Affinity Capture-MS Homo sapiens
381 INF2 64423
Affinity Capture-MS Homo sapiens
382 CNN3 1266
Co-fractionation Homo sapiens
383 FLNA 2316
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
384 MYO1E 4643
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
385 SERBP1 26135
Affinity Capture-MS Homo sapiens
386 CD44 960
Affinity Capture-MS Homo sapiens
387 RAC1 5879
Two-hybrid Homo sapiens
388 ATXN3 4287
Affinity Capture-MS Homo sapiens
389 COPS4 51138
Co-fractionation Homo sapiens
390 VIM 7431
Co-fractionation Homo sapiens
391 IARS2 55699
Affinity Capture-MS Homo sapiens
392 EP300 2033
Affinity Capture-MS Homo sapiens
393 UBE2H 7328
Affinity Capture-MS Homo sapiens
394 INSIG1  
Affinity Capture-MS Homo sapiens
395 SLFN11 91607
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
396 ACTR2 10097
Affinity Capture-MS Homo sapiens
397 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
398 AP2B1 163
Affinity Capture-MS Homo sapiens
399 CASP4  
Two-hybrid Homo sapiens
400 TWF2 11344
Affinity Capture-MS Homo sapiens
401 LGR4 55366
Affinity Capture-MS Homo sapiens
402 CEP89 84902
Affinity Capture-MS Homo sapiens
403 ARPC5L 81873
Affinity Capture-MS Homo sapiens
404 TRAF4 9618
Affinity Capture-MS Homo sapiens
405 TUBB4B 10383
Co-fractionation Homo sapiens
406 TNPO1 3842
Co-fractionation Homo sapiens
407 COPS5 10987
Co-fractionation Homo sapiens
408 PSMD11 5717
Co-fractionation Homo sapiens
409 POFUT1 23509
Cross-Linking-MS (XL-MS) Homo sapiens
410 SPECC1 92521
Affinity Capture-MS Homo sapiens
411 PHLPP1  
Proximity Label-MS Homo sapiens
412 FBXO25  
Affinity Capture-MS Homo sapiens
413 HSPA1L 3305
Co-fractionation Homo sapiens
414 PPIA 5478
Affinity Capture-MS Homo sapiens
415 CALM1 801
Affinity Capture-MS Homo sapiens
416 CFL1 1072
Affinity Capture-MS Homo sapiens
417 SNRPD2 6633
Co-fractionation Homo sapiens
418 HSPA5 3309
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
419 USP36  
Affinity Capture-MS Homo sapiens
420 KIAA1429 25962
Affinity Capture-MS Homo sapiens
421 RNH1 6050
Co-fractionation Homo sapiens
422 VTA1 51534
Co-fractionation Homo sapiens
423 PPP1R12A 4659
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
424 SPECC1L 23384
Affinity Capture-MS Homo sapiens
425 KIF5B 3799
Co-fractionation Homo sapiens
426 YES1 7525
Affinity Capture-MS Homo sapiens
427 FBXW7  
Affinity Capture-MS Homo sapiens
428 CD109 135228
Affinity Capture-MS Homo sapiens
429 AGO3  
Affinity Capture-MS Homo sapiens
430 PSMC6 5706
Co-fractionation Homo sapiens
431 ATP5O 539
Affinity Capture-MS Homo sapiens
432 CEP162  
Affinity Capture-MS Homo sapiens
433 ALK 238
Affinity Capture-MS Homo sapiens
434 MYO1B 4430
Affinity Capture-MS Homo sapiens
435 USP45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
436 EED  
Affinity Capture-MS Homo sapiens
437 ATP13A2  
Affinity Capture-MS Homo sapiens
438 CDC73  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
439 MARK4  
Affinity Capture-MS Homo sapiens
440 MYCN  
Affinity Capture-MS Homo sapiens
441 OCLM  
Affinity Capture-MS Homo sapiens
442 RLIM 51132
Affinity Capture-MS Homo sapiens
443 FCF1  
Affinity Capture-MS Homo sapiens
444 SMC4 10051
Co-fractionation Homo sapiens
445 WDR1 9948
Affinity Capture-MS Homo sapiens
446 WIPF1 7456
Co-fractionation Homo sapiens
447 PPP1CA 5499
Affinity Capture-MS Homo sapiens
448 RBBP7 5931
Co-fractionation Homo sapiens
449 EMD 2010
Affinity Capture-MS Homo sapiens
450 TGM2 7052
Co-fractionation Homo sapiens
451 NARFL 64428
Affinity Capture-MS Homo sapiens
452 TMOD1  
Affinity Capture-MS Homo sapiens
453 PSMC1 5700
Co-fractionation Homo sapiens
454 TNKS1BP1 85456
Co-fractionation Homo sapiens
455 LRRFIP2 9209
Affinity Capture-MS Homo sapiens
456 UBE2I 7329
Biochemical Activity Homo sapiens
457 BMP2K 55589
Affinity Capture-MS Homo sapiens
458 MYH10 4628
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
459 MYH11 4629
Cross-Linking-MS (XL-MS) Homo sapiens
460 H2AFY 9555
Affinity Capture-MS Homo sapiens
461 ACBD3 64746
Co-fractionation Homo sapiens
462 CALML3 810
Affinity Capture-MS Homo sapiens
463 ARRB1 408
Affinity Capture-MS Homo sapiens
464 LIMA1 51474
Affinity Capture-MS Homo sapiens
465 ACTN1 87
Affinity Capture-MS Homo sapiens
466 GOLGA3 2802
Co-fractionation Homo sapiens
467 COPS2 9318
Co-fractionation Homo sapiens
468 CLINT1 9685
Affinity Capture-MS Homo sapiens
469 FANCD2  
Affinity Capture-MS Homo sapiens
470 ACTBL2 345651
Affinity Capture-MS Homo sapiens
471 EIF4G1 1981
Co-fractionation Homo sapiens
472 RNF170 81790
Affinity Capture-MS Homo sapiens
473 CDCA8 55143
Affinity Capture-MS Homo sapiens
474 LETM1 3954
Affinity Capture-MS Homo sapiens
475 CTNNB1 1499
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
476 COPS8 10920
Co-fractionation Homo sapiens
477 CTTN 2017
Affinity Capture-MS Homo sapiens
478 NAP1L1 4673
Affinity Capture-MS Homo sapiens
479 UACA 55075
Affinity Capture-MS Homo sapiens
480 HIP1R 9026
Affinity Capture-MS Homo sapiens
481 SF3A1 10291
Cross-Linking-MS (XL-MS) Homo sapiens
482 AURKB 9212
Affinity Capture-MS Homo sapiens
483 LZTS2 84445
Affinity Capture-MS Homo sapiens
484 PRKACA 5566
Affinity Capture-MS Homo sapiens
485 MYL6B 140465
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
486 MYO6 4646
Affinity Capture-MS Homo sapiens
487 NDUFB3 4709
Affinity Capture-MS Homo sapiens
488 FCHO2 115548
Affinity Capture-MS Homo sapiens
489 SAMD9 54809
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
490 MOB2 81532
Affinity Capture-MS Homo sapiens
491 CLTC 1213
Affinity Capture-MS Homo sapiens
492 PLEKHG3 26030
Affinity Capture-MS Homo sapiens
493 TSGA10  
Affinity Capture-MS Homo sapiens
494 MTHFD1L 25902
Affinity Capture-MS Homo sapiens
495 GSN 2934
Affinity Capture-MS Homo sapiens
496 MYO1C 4641
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
497 PDLIM7 9260
Affinity Capture-MS Homo sapiens
498 ARRB2 409
Affinity Capture-MS Homo sapiens
499 SPTAN1 6709
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
500 MYLK 4638
Affinity Capture-MS Homo sapiens
501 PSMD1 5707
Co-fractionation Homo sapiens
502 SVIL 6840
Affinity Capture-MS Homo sapiens
503 TNFAIP1 7126
Affinity Capture-MS Homo sapiens
504 DNAJA2 10294
Co-fractionation Homo sapiens
505 CXCL6  
Affinity Capture-MS Homo sapiens
506 BOP1 23246
Affinity Capture-MS Homo sapiens
507 TTLL6  
Affinity Capture-MS Homo sapiens
508 HDAC1 3065
Co-fractionation Homo sapiens
509 CHD4 1108
Co-fractionation Homo sapiens
510 EIF4A3 9775
Affinity Capture-MS Homo sapiens
511 EPB41L2 2037
Co-fractionation Homo sapiens
512 TERF1 7013
Affinity Capture-MS Homo sapiens
513 MICAL3 57553
Affinity Capture-MS Homo sapiens
514 CAD 790
Co-fractionation Homo sapiens
515 RXRA 6256
Affinity Capture-MS Homo sapiens
516 TRIM31  
Affinity Capture-MS Homo sapiens
517 PINK1  
Affinity Capture-MS Homo sapiens
518 RPS8 6202
Cross-Linking-MS (XL-MS) Homo sapiens
519 DOCK7 85440
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
520 ZBTB20 26137
Affinity Capture-MS Homo sapiens
521 PIK3R2 5296
Affinity Capture-MS Homo sapiens
522 PEX5 5830
Affinity Capture-MS Homo sapiens
523 HNRNPU 3192
Co-fractionation Homo sapiens
524 CDC5L 988
Affinity Capture-MS Homo sapiens
525 METTL17  
Affinity Capture-MS Homo sapiens
526 IVNS1ABP  
Affinity Capture-MS Homo sapiens
527 DSG2 1829
Affinity Capture-MS Homo sapiens
528 Myl12a  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which MYH9 is involved
PathwayEvidenceSource
Anti-inflammatory response favouring Leishmania parasite infection TAS Reactome
Axon guidance IEA Reactome
CD163 mediating an anti-inflammatory response TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers TAS Reactome
EPH-Ephrin signaling IEA Reactome
EPHA-mediated growth cone collapse IEA Reactome
Fcgamma receptor (FCGR) dependent phagocytosis TAS Reactome
FCGR3A-mediated phagocytosis TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Innate Immune System TAS Reactome
Leishmania infection TAS Reactome
Leishmania parasite growth and survival TAS Reactome
Leishmania phagocytosis TAS Reactome
Membrane Trafficking IEA Reactome
Nervous system development IEA Reactome
Parasite infection TAS Reactome
Parasitic Infection Pathways TAS Reactome
Regulation of actin dynamics for phagocytic cup formation TAS Reactome
RHO GTPase Effectors IEA Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases activate CIT IEA Reactome
RHO GTPases activate PAKs IEA Reactome
RHO GTPases activate PAKs TAS Reactome
RHO GTPases activate PKNs IEA Reactome
RHO GTPases Activate ROCKs IEA Reactome
Sema4D in semaphorin signaling IEA Reactome
Sema4D induced cell migration and growth-cone collapse IEA Reactome
Semaphorin interactions IEA Reactome
Sensory Perception IEA Reactome
Sensory processing of sound IEA Reactome
Sensory processing of sound by inner hair cells of the cochlea IEA Reactome
Sensory processing of sound by outer hair cells of the cochlea IEA Reactome
Signal Transduction IEA Reactome
Signal Transduction TAS Reactome
Signaling by ALK fusions and activated point mutants TAS Reactome
Signaling by ALK in cancer TAS Reactome
Signaling by Rho GTPases IEA Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 IEA Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Translocation of SLC2A4 (GLUT4) to the plasma membrane IEA Reactome
Vesicle-mediated transport IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here