|
 Gene description for MOB1B |
| Gene name |
MOB kinase activator 1B |
| Gene symbol |
MOB1B |
| Other names/aliases |
MATS2
MOB4A
MOBKL1A |
| Species |
Homo sapiens |
| Database cross references - MOB1B |
| ExoCarta |
ExoCarta_92597 |
| Entrez Gene |
92597 |
| HGNC |
29801 |
| MIM |
609282 |
| UniProt |
Q7L9L4
|
| MOB1B identified in exosomes derived from the following tissue/cell type |
|
Colorectal cancer cells
|
19837982
|
|
Platelets
|
25332113
|
|
Platelets
|
25332113
|
|
Platelets
|
25332113
|
|
Thymus
|
23844026
|
|
Urine
|
15326289
|
| Gene ontology annotations for MOB1B |
|
|
| Experiment description of studies that identified MOB1B in exosomes |
| 1 |
| Experiment ID |
21 |
| ISEV standards |
|
✔
EM|IEM
|
EV Biophysical techniques |
|
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
|
✔
CD63
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
|
| PubMed ID |
19837982
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. |
| Authors |
Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson |
| Journal name |
MCP
|
| Publication year |
2009 |
| Sample |
Colorectal cancer cells |
| Sample name |
LIM1215 |
| Isolation/purification methods |
Filtration
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.10-1.12 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [Orbitrap]
Western blotting |
|
|
| 2 |
| Experiment ID |
231 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✔
Alix
|
EV Cytosolic markers |
|
✔
CD63|CD9
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✔
NTA
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
25332113
|
| Organism |
Homo sapiens |
| Experiment description |
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets |
| Authors |
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G. |
| Journal name |
Transfusion
|
| Publication year |
2015 |
| Sample |
Platelets |
| Sample name |
PL-Exs - Rep 1 |
| Isolation/purification methods |
Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient |
| Flotation density |
1.12-1.15 g/mL
|
| Molecules identified in the study |
Protein
Lipids |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 3 |
| Experiment ID |
232 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
25332113
|
| Organism |
Homo sapiens |
| Experiment description |
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets |
| Authors |
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G. |
| Journal name |
Transfusion
|
| Publication year |
2015 |
| Sample |
Platelets |
| Sample name |
PL-Exs - Rep 2 |
| Isolation/purification methods |
Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient |
| Flotation density |
1.12-1.15 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 4 |
| Experiment ID |
233 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
25332113
|
| Organism |
Homo sapiens |
| Experiment description |
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets |
| Authors |
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G. |
| Journal name |
Transfusion
|
| Publication year |
2015 |
| Sample |
Platelets |
| Sample name |
PL-Exs - Rep 3 |
| Isolation/purification methods |
Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient |
| Flotation density |
1.12-1.15 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 5 |
| Experiment ID |
217 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
TSG101
|
EV Cytosolic markers |
|
✔
CD81|CD9|CD63
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✔
NTA
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
23844026
|
| Organism |
Homo sapiens |
| Experiment description |
Characterization of human thymic exosomes. |
| Authors |
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
| Journal name |
PLoS One
|
| Publication year |
2013 |
| Sample |
Thymus |
| Sample name |
Normal-Thymus |
| Isolation/purification methods |
Differential centrifugation
Filtration
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 6 |
| Experiment ID |
13 |
| ISEV standards |
|
✔
IEM
|
EV Biophysical techniques |
|
✔
Alix|RAB4|RAB5B|RAB11|TSG101
|
EV Cytosolic markers |
|
✔
CD9|AQP2|AQP1
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
15326289
|
| Organism |
Homo sapiens |
| Experiment description |
Identification and proteomic profiling of exosomes in human urine. |
| Authors |
Pisitkun T, Shen RF, Knepper MA |
| Journal name |
PNAS
|
| Publication year |
2004 |
| Sample |
Urine |
| Sample name |
Urine - Normal |
| Isolation/purification methods |
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [LCQ DECA XP]
Western blotting |
|
|
| Protein-protein interactions for MOB1B |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which MOB1B is involved |
|
|
|
