Gene description for RASSF2
Gene name Ras association (RalGDS/AF-6) domain family member 2
Gene symbol RASSF2
Other names/aliases CENP-34
RASFADIN
Species Homo sapiens
 Database cross references - RASSF2
ExoCarta ExoCarta_9770
Entrez Gene 9770
HGNC 9883
MIM 609492
UniProt P50749  
 RASSF2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RASSF2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    ossification GO:0001503 IEA
    skeletal system development GO:0001501 IEA
    regulation of osteoblast differentiation GO:0045667 IEA
    cell cycle GO:0007049 IEA
    regulation of osteoclast differentiation GO:0045670 IEA
    homeostasis of number of cells GO:0048872 IEA
    negative regulation of NIK/NF-kappaB signaling GO:1901223 IEA
    bone remodeling GO:0046849 IEA
    epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade GO:0038168 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified RASSF2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RASSF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RASSF5 83593
Reconstituted Complex Homo sapiens
2 KRAS 3845
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which RASSF2 is involved
No pathways found





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