Experiment description of studies that identified CALML3 in exosomes

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 217 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|CD81|CD9|CD63 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O." Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 63 MISEV standards ✘ Biophysical techniques ✔ AQP2 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19056867     Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA" Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

Protein-protein interactions for CALML3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 DUSP22   Affinity Capture-MS Homo sapiens 2 ARHGAP21 57584 Affinity Capture-MS Homo sapiens 3 CCDC94   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 C15orf40   Affinity Capture-MS Homo sapiens 5 SQRDL 58472 Affinity Capture-MS Homo sapiens 6 PPP1CB 5500 Affinity Capture-MS Homo sapiens 7 CX3CL1   Affinity Capture-MS Homo sapiens 8 VTI1B 10490 Affinity Capture-MS Homo sapiens 9 HMCES   Affinity Capture-MS Homo sapiens 10 FBXL4 26235 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 DCTN6 10671 Affinity Capture-MS Homo sapiens 12 NRSN1   Affinity Capture-MS Homo sapiens 13 TEX35   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 CD72   Affinity Capture-MS Homo sapiens 15 BTF3 689 Affinity Capture-MS Homo sapiens 16 C19orf54   Affinity Capture-MS Homo sapiens 17 UNC13B 10497 Affinity Capture-MS Homo sapiens 18 ARL15 54622 Affinity Capture-MS Homo sapiens 19 CDK15   Affinity Capture-MS Homo sapiens 20 GAK 2580 Affinity Capture-MS Homo sapiens 21 C9orf40   Affinity Capture-MS Homo sapiens 22 CAMK1 8536 Affinity Capture-MS Homo sapiens 23 ZNF354C   Affinity Capture-MS Homo sapiens 24 SEMG2 6407 Affinity Capture-MS Homo sapiens 25 CALM1 801 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 TERF2IP 54386 Two-hybrid Homo sapiens 27 CCNB1IP1   Affinity Capture-MS Homo sapiens 28 FHOD1 29109 Affinity Capture-MS Homo sapiens 29 EIF4E2   Affinity Capture-MS Homo sapiens 30 ST6GALNAC6 30815 Affinity Capture-MS Homo sapiens 31 FNDC5   Affinity Capture-MS Homo sapiens 32 PI4KA 5297 Affinity Capture-MS Homo sapiens 33 SATB2   Affinity Capture-MS Homo sapiens 34 INTS9 55756 Affinity Capture-MS Homo sapiens 35 PPP1CC 5501 Affinity Capture-MS Homo sapiens 36 ANXA9   Affinity Capture-MS Homo sapiens 37 DHRS12   Affinity Capture-MS Homo sapiens 38 FBXO3   Affinity Capture-MS Homo sapiens 39 DGCR14   Affinity Capture-MS Homo sapiens 40 KIF23 9493 Affinity Capture-MS Homo sapiens 41 IL31RA   Affinity Capture-MS Homo sapiens 42 EFNB3 1949 Affinity Capture-MS Homo sapiens 43 E2F6 1876 Affinity Capture-MS Homo sapiens 44 NUDT3 11165 Affinity Capture-MS Homo sapiens 45 IQGAP1 8826 Affinity Capture-MS Homo sapiens 46 TNFRSF19   Affinity Capture-MS Homo sapiens 47 OBSL1 23363 Affinity Capture-MS Homo sapiens 48 NT5C3A 51251 Affinity Capture-MS Homo sapiens 49 KIAA1551   Affinity Capture-MS Homo sapiens 50 ADAT2   Affinity Capture-MS Homo sapiens 51 C11orf65   Two-hybrid Homo sapiens 52 USF2 7392 Affinity Capture-MS Homo sapiens 53 GDF5 8200 Affinity Capture-MS Homo sapiens 54 HINT3 135114 Affinity Capture-MS Homo sapiens 55 PHF11 51131 Affinity Capture-MS Homo sapiens 56 SFMBT1 51460 Affinity Capture-MS Homo sapiens 57 PKN3 29941 Affinity Capture-MS Homo sapiens 58 KLHL11   Affinity Capture-MS Homo sapiens 59 MAPK4   Two-hybrid Homo sapiens 60 ARNT2   Affinity Capture-MS Homo sapiens 61 ELMO1 9844 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 GNPAT 8443 Affinity Capture-MS Homo sapiens 63 C18orf21   Affinity Capture-MS Homo sapiens 64 RSPH10B2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 FCF1   Affinity Capture-MS Homo sapiens 66 C7orf55   Affinity Capture-MS Homo sapiens 67 RASSF2 9770 Affinity Capture-MS Homo sapiens 68 DDX19B 11269 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 CALM2 805 Affinity Capture-MS Homo sapiens 70 COASY 80347 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 71 TCEAL8   Affinity Capture-MS Homo sapiens 72 KIAA1211   Affinity Capture-MS Homo sapiens 73 NAA50 80218 Affinity Capture-MS Homo sapiens 74 C16orf70   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 PARK2   Affinity Capture-MS Homo sapiens 76 ZDHHC19   Affinity Capture-MS Homo sapiens 77 FUNDC2 65991 Affinity Capture-MS Homo sapiens 78 MAPRE1 22919 Affinity Capture-MS Homo sapiens 79 RNF115   Affinity Capture-MS Homo sapiens 80 SRRT 51593 Affinity Capture-MS Homo sapiens 81 PEMT   Affinity Capture-MS Homo sapiens 82 CAMK1D 57118 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 83 KIAA1683   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 84 PYHIN1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 85 MTMR7   Affinity Capture-MS Homo sapiens 86 MYH9 4627 Affinity Capture-MS Homo sapiens 87 LRCH1 23143 Affinity Capture-MS Homo sapiens 88 SARAF   Affinity Capture-MS Homo sapiens 89 SCAMP2 10066 Affinity Capture-MS Homo sapiens 90 PIGT 51604 Affinity Capture-MS Homo sapiens 91 IK 3550 Affinity Capture-MS Homo sapiens 92 ANAPC10   Affinity Capture-MS Homo sapiens 93 ARNT 405 Affinity Capture-MS Homo sapiens 94 BCL2L12 83596 Affinity Capture-MS Homo sapiens 95 SSUH2   Affinity Capture-MS Homo sapiens 96 MTPAP 55149 Affinity Capture-MS Homo sapiens 97 TPP2 7174 Affinity Capture-MS Homo sapiens 98 PML 5371 Affinity Capture-MS Homo sapiens 99 OR51E2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 100 UPK1A 11045 Affinity Capture-MS Homo sapiens 101 SCN3B   Affinity Capture-MS Homo sapiens 102 QSER1   Affinity Capture-MS Homo sapiens 103 RAD21 5885 Affinity Capture-Western Homo sapiens 104 KIF2C 11004 Affinity Capture-MS Homo sapiens 105 GPATCH11   Affinity Capture-MS Homo sapiens 106 FSTL1 11167 Affinity Capture-MS Homo sapiens 107 CCDC12   Affinity Capture-MS Homo sapiens 108 POLG2   Affinity Capture-MS Homo sapiens 109 GRAMD1A   Affinity Capture-MS Homo sapiens 110 ANLN 54443 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 111 RHBDD1 84236 Affinity Capture-MS Homo sapiens 112 CAMKMT   Affinity Capture-MS Homo sapiens 113 PPP2R2B 5521 Affinity Capture-MS Homo sapiens 114 GFER   Affinity Capture-MS Homo sapiens 115 SUGP1   Affinity Capture-MS Homo sapiens 116 ERLEC1 27248 Affinity Capture-MS Homo sapiens 117 MUS81   Affinity Capture-MS Homo sapiens 118 AGPAT1 10554 Affinity Capture-MS Homo sapiens 119 ZFPL1 7542 Affinity Capture-MS Homo sapiens 120 USP15 9958 Affinity Capture-MS Homo sapiens 121 JOSD1   Affinity Capture-MS Homo sapiens 122 ECT2 1894 Affinity Capture-MS Homo sapiens 123 FAM60A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 124 CCDC82   Affinity Capture-MS Homo sapiens 125 IQCB1   Two-hybrid Homo sapiens 126 PCP4   Affinity Capture-MS Homo sapiens 127 ZSCAN12   Affinity Capture-MS Homo sapiens 128 UBE3B 89910 Affinity Capture-MS Homo sapiens 129 BHLHE40   Two-hybrid Homo sapiens 130 ZC3HC1   Affinity Capture-MS Homo sapiens 131 FOXN3 1112 Affinity Capture-MS Homo sapiens 132 PHKG2 5261 Affinity Capture-MS Homo sapiens 133 HNRNPA1 3178 Affinity Capture-MS Homo sapiens 134 SAMD1   Affinity Capture-MS Homo sapiens 135 FTH1 2495 Affinity Capture-MS Homo sapiens 136 PLD5   Affinity Capture-MS Homo sapiens 137 TMEM74   Affinity Capture-MS Homo sapiens 138 EHBP1 23301 Affinity Capture-MS Homo sapiens 139 SUSD3 203328 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 140 ADH1C 126 Affinity Capture-MS Homo sapiens 141 PLEKHA5 54477 Affinity Capture-MS Homo sapiens 142 SF3A1 10291 Affinity Capture-MS Homo sapiens 143 KDM3B   Affinity Capture-MS Homo sapiens 144 FRMD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 145 FOS 2353 Affinity Capture-MS Homo sapiens 146 MYC   Affinity Capture-MS Homo sapiens 147 HECW2   Affinity Capture-MS Homo sapiens 148 UHRF1BP1 54887 Affinity Capture-MS Homo sapiens 149 RAB11B 9230 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 150 HSDL2 84263 Affinity Capture-MS Homo sapiens 151 SCAF11   Affinity Capture-MS Homo sapiens 152 SGIP1   Affinity Capture-MS Homo sapiens 153 LRCH2   Affinity Capture-MS Homo sapiens 154 GMCL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 155 LGALS7 3963 Affinity Capture-MS Homo sapiens 156 SLC37A4 2542 Affinity Capture-MS Homo sapiens 157 STX17 55014 Affinity Capture-MS Homo sapiens 158 CAMK2G 818 Affinity Capture-MS Homo sapiens 159 RIPPLY3   Affinity Capture-MS Homo sapiens 160 TMEM31   Affinity Capture-MS Homo sapiens 161 ATP2B3 492 Affinity Capture-MS Homo sapiens 162 CXorf66   Affinity Capture-MS Homo sapiens 163 MYO1C 4641 Affinity Capture-MS Homo sapiens 164 PDLIM7 9260 Affinity Capture-MS Homo sapiens 165 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 166 KIAA0907   Affinity Capture-MS Homo sapiens 167 SLC25A6 293 Affinity Capture-MS Homo sapiens 168 LIG3 3980 Affinity Capture-MS Homo sapiens 169 SSFA2 6744 Affinity Capture-MS Homo sapiens 170 RBM24 221662 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 171 USP1 7398 Affinity Capture-MS Homo sapiens 172 CCDC102A 92922 Affinity Capture-MS Homo sapiens 173 ISCA2 122961 Affinity Capture-MS Homo sapiens 174 ISOC2   Two-hybrid Homo sapiens 175 EPHA4 2043 Affinity Capture-MS Homo sapiens 176 SCAF8 22828 Affinity Capture-MS Homo sapiens 177 FLYWCH2   Affinity Capture-MS Homo sapiens 178 EMC4 51234 Affinity Capture-MS Homo sapiens 179 C17orf105   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 180 CAPZA2 830 Affinity Capture-MS Homo sapiens 181 NHLRC2 374354 Affinity Capture-MS Homo sapiens 182 C1orf35   Affinity Capture-MS Homo sapiens 183 SSBP2   Affinity Capture-MS Homo sapiens 184 ITPR3 3710 Affinity Capture-MS Homo sapiens 185 PTDSS1 9791 Affinity Capture-MS Homo sapiens 186 FBXO44   Affinity Capture-MS Homo sapiens 187 ARFIP2 23647 Affinity Capture-MS Homo sapiens 188 MKI67   Affinity Capture-MS Homo sapiens 189 FAM227B   Affinity Capture-MS Homo sapiens 190 ZNF280C   Affinity Capture-MS Homo sapiens 191 ERCC3   Affinity Capture-MS Homo sapiens 192 MBNL1 4154 Affinity Capture-MS Homo sapiens 193 PDLIM5 10611 Affinity Capture-MS Homo sapiens 194 KIR3DS1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 195 LDB1   Affinity Capture-MS Homo sapiens 196 EZH2   Affinity Capture-MS Homo sapiens 197 KDELR2 11014 Affinity Capture-MS Homo sapiens 198 IQGAP2 10788 Affinity Capture-MS Homo sapiens 199 PINK1   Affinity Capture-MS Homo sapiens 200 GPR18   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 201 GOT1 2805 Affinity Capture-MS Homo sapiens 202 TNNC2   Affinity Capture-MS Homo sapiens 203 RAC3 5881 Affinity Capture-MS Homo sapiens 204 STMN3   Affinity Capture-MS Homo sapiens 205 ITPR1 3708 Affinity Capture-MS Homo sapiens 206 PDE4DIP 9659 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 207 SNW1 22938 Affinity Capture-MS Homo sapiens 208 SH2D4A 63898 Affinity Capture-MS Homo sapiens 209 OR2A4 79541 Affinity Capture-MS Homo sapiens 210 ARHGAP8 23779 Affinity Capture-MS Homo sapiens 211 GABPA 2551 Affinity Capture-MS Homo sapiens 212 CCR1   Affinity Capture-MS Homo sapiens 213 SKA2   Affinity Capture-MS Homo sapiens 214 P2RX6   Affinity Capture-MS Homo sapiens 215 CSGALNACT1 55790 Affinity Capture-MS Homo sapiens 216 POC5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which CALML3 is involved

No pathways found