Gene description for BTF3
Gene name basic transcription factor 3
Gene symbol BTF3
Other names/aliases BETA-NAC
BTF3a
BTF3b
NACB
Species Homo sapiens
 Database cross references - BTF3
ExoCarta ExoCarta_689
Entrez Gene 689
HGNC 1125
MIM 602542
UniProt P20290  
 BTF3 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for BTF3
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
Biological Process
    protein transport GO:0015031 IEA
    transcription from RNA polymerase II promoter GO:0006366 TAS
    regulation of transcription, DNA-templated GO:0006355 IEA
    in utero embryonic development GO:0001701 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified BTF3 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for BTF3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CSNK2B 1460
Invitro Homo sapiens
Two-hybrid Homo sapiens
2 SURB7  
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which BTF3 is involved
No pathways found





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