Gene description for LMNB1
Gene name lamin B1
Gene symbol LMNB1
Other names/aliases ADLD
LMN
LMN2
LMNB
Species Homo sapiens
 Database cross references - LMNB1
ExoCarta ExoCarta_4001
Vesiclepedia VP_4001
Entrez Gene 4001
HGNC 6637
MIM 150340
UniProt P20700  
 LMNB1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for LMNB1
Molecular Function
    structural constituent of cytoskeleton GO:0005200 IBA
    protein binding GO:0005515 IPI
    phospholipase binding GO:0043274 IEA
    structural constituent of nuclear lamina GO:0160123 TAS
    sequence-specific double-stranded DNA binding GO:1990837 IEA
Biological Process
    nuclear envelope organization GO:0006998 IBA
    nuclear envelope organization GO:0006998 IMP
    cytoskeleton organization GO:0007010 IEA
    nuclear migration GO:0007097 IBA
    heterochromatin formation GO:0031507 IBA
    nuclear pore localization GO:0051664 IBA
    protein localization to nuclear envelope GO:0090435 IBA
Subcellular Localization
    nucleus GO:0005634 IDA
    nuclear envelope GO:0005635 IDA
    nuclear envelope GO:0005635 TAS
    nuclear inner membrane GO:0005637 IEA
    lamin filament GO:0005638 IEA
    nuclear lamina GO:0005652 IBA
    nuclear lamina GO:0005652 IMP
    nucleoplasm GO:0005654 TAS
    membrane GO:0016020 HDA
    nuclear matrix GO:0016363 IEA
    nuclear membrane GO:0031965 HDA
    nuclear membrane GO:0031965 IDA
 Experiment description of studies that identified LMNB1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
25
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for LMNB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
4 CDCA2 157313
Proximity Label-MS Homo sapiens
5 GJD3  
Proximity Label-MS Homo sapiens
6 KPNA1 3836
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 PRPF8 10594
Affinity Capture-MS Homo sapiens
8 RIN3  
Affinity Capture-MS Homo sapiens
9 RCL1 10171
Affinity Capture-MS Homo sapiens
10 HNRNPK 3190
Co-fractionation Homo sapiens
11 JPH1 56704
Proximity Label-MS Homo sapiens
12 VMP1 81671
Proximity Label-MS Homo sapiens
13 MTG2  
Proximity Label-MS Homo sapiens
14 KIF20A 10112
Affinity Capture-MS Homo sapiens
15 SNRNP40 9410
Affinity Capture-MS Homo sapiens
16 UBC 7316
Affinity Capture-MS Homo sapiens
17 CSE1L 1434
Affinity Capture-MS Homo sapiens
18 KPNA2 3838
Affinity Capture-MS Homo sapiens
19 TAF15 8148
Affinity Capture-MS Homo sapiens
20 SOX2  
Affinity Capture-MS Homo sapiens
21 CENPA  
Proximity Label-MS Homo sapiens
22 CKB 1152
Co-fractionation Homo sapiens
23 KBTBD6  
Proximity Label-MS Homo sapiens
24 DDX23 9416
Affinity Capture-MS Homo sapiens
25 WDR76  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
26 CRNKL1 51340
Affinity Capture-MS Homo sapiens
27 NUP153 9972
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 AGGF1  
Proximity Label-MS Homo sapiens
29 CPSF7 79869
Affinity Capture-MS Homo sapiens
30 MARCH5  
Proximity Label-MS Homo sapiens
31 DNAJB1 3337
Affinity Capture-MS Homo sapiens
32 HELLS 3070
Proximity Label-MS Homo sapiens
33 SLC25A46 91137
Proximity Label-MS Homo sapiens
34 ZWINT  
Affinity Capture-MS Homo sapiens
35 MECP2 4204
Affinity Capture-MS Homo sapiens
36 SREK1 140890
Affinity Capture-MS Homo sapiens
37 SOD1 6647
Affinity Capture-MS Homo sapiens
38 KIF14 9928
Affinity Capture-MS Homo sapiens
39 CAMLG 819
Proximity Label-MS Homo sapiens
40 CHMP4C 92421
Affinity Capture-MS Homo sapiens
41 SENP2 59343
Proximity Label-MS Homo sapiens
42 ZNF444  
Affinity Capture-MS Homo sapiens
43 TMX1 81542
Proximity Label-MS Homo sapiens
44 GGT7 2686
Proximity Label-MS Homo sapiens
45 SUPT5H 6829
Affinity Capture-MS Homo sapiens
46 C17orf49 124944
Affinity Capture-MS Homo sapiens
47 FAM162A 26355
Affinity Capture-MS Homo sapiens
48 CIRH1A 84916
Affinity Capture-MS Homo sapiens
49 YAP1 10413
Affinity Capture-MS Homo sapiens
50 CBX5 23468
Affinity Capture-MS Homo sapiens
51 BANF1 8815
Affinity Capture-MS Homo sapiens
52 YWHAQ 10971
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
53 Hnrnpf 98758
Affinity Capture-MS Mus musculus
54 WHSC1L1  
Proximity Label-MS Homo sapiens
55 DDX39B 7919
Affinity Capture-MS Homo sapiens
56 AHCTF1 25909
Proximity Label-MS Homo sapiens
57 SEC61B 10952
Proximity Label-MS Homo sapiens
58 REEP5 7905
Proximity Label-MS Homo sapiens
59 ANLN 54443
Affinity Capture-MS Homo sapiens
60 TMPO 7112
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
61 DZIP3  
Affinity Capture-MS Homo sapiens
62 DHCR7 1717
Proximity Label-MS Homo sapiens
63 SDHA 6389
Affinity Capture-MS Homo sapiens
64 DLG1 1739
Affinity Capture-MS Homo sapiens
65 BCAP31 10134
Proximity Label-MS Homo sapiens
66 TMEM199  
Proximity Label-MS Homo sapiens
67 ATP6AP2 10159
Proximity Label-MS Homo sapiens
68 THOC7 80145
Affinity Capture-MS Homo sapiens
69 SLTM 79811
Affinity Capture-MS Homo sapiens
70 GTF3C4 9329
Proximity Label-MS Homo sapiens
71 FN1 2335
Affinity Capture-MS Homo sapiens
72 ZNF512  
Proximity Label-MS Homo sapiens
73 SOAT1 6646
Proximity Label-MS Homo sapiens
74 HECW2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
75 DLST 1743
Affinity Capture-MS Homo sapiens
76 LMF2 91289
Proximity Label-MS Homo sapiens
77 HSPA4 3308
Co-fractionation Homo sapiens
78 HIST1H1A 3024
Co-fractionation Homo sapiens
79 FAM169A  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
80 NDUFA3  
Affinity Capture-MS Homo sapiens
81 ILK 3611
Affinity Capture-MS Homo sapiens
82 KRT19 3880
Proximity Label-MS Homo sapiens
83 HIST1H2AJ 8331
Affinity Capture-MS Homo sapiens
84 NES 10763
Affinity Capture-MS Homo sapiens
85 RRP36 88745
Affinity Capture-MS Homo sapiens
86 TP53BP2  
Two-hybrid Homo sapiens
87 BCAS2 10286
Affinity Capture-MS Homo sapiens
88 NDUFAF2  
Affinity Capture-MS Homo sapiens
89 TMEM57  
Proximity Label-MS Homo sapiens
90 RBM25 58517
Affinity Capture-MS Homo sapiens
91 ABCG8  
Two-hybrid Homo sapiens
92 CDC37 11140
Co-fractionation Homo sapiens
93 RRP1 8568
Affinity Capture-MS Homo sapiens
94 KPNA6 23633
Affinity Capture-MS Homo sapiens
95 DCTN2 10540
Co-fractionation Homo sapiens
96 BMPR1A 657
Affinity Capture-MS Homo sapiens
97 ITPR3 3710
Proximity Label-MS Homo sapiens
98 H2AFY 9555
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 RABL3 285282
Proximity Label-MS Homo sapiens
100 HM13 81502
Proximity Label-MS Homo sapiens
101 HOXA13  
Proximity Label-MS Homo sapiens
102 HNRNPL 3191
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
103 NDC1 55706
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 RAB11A 8766
Proximity Label-MS Homo sapiens
105 FAM50A 9130
Proximity Label-MS Homo sapiens
106 CISD2 493856
Proximity Label-MS Homo sapiens
107 CUL7 9820
Affinity Capture-MS Homo sapiens
108 RAB5C 5878
Proximity Label-MS Homo sapiens
109 PRAF2 11230
Proximity Label-MS Homo sapiens
110 NUP85 79902
Proximity Label-MS Homo sapiens
111 ZNF362  
Proximity Label-MS Homo sapiens
112 PCYT1A 5130
Proximity Label-MS Homo sapiens
113 RANGAP1 5905
Affinity Capture-MS Homo sapiens
114 DERL1 79139
Proximity Label-MS Homo sapiens
115 NSDHL 50814
Proximity Label-MS Homo sapiens
116 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
117 COX5A 9377
Affinity Capture-MS Homo sapiens
118 RSL1D1 26156
Affinity Capture-MS Homo sapiens
119 SPRTN  
Affinity Capture-MS Homo sapiens
120 METTL7A 25840
Proximity Label-MS Homo sapiens
121 LAMP3  
Proximity Label-MS Homo sapiens
122 KIAA0020 9933
Affinity Capture-MS Homo sapiens
123 GJA1 2697
Proximity Label-MS Homo sapiens
124 KCTD10 83892
Affinity Capture-MS Homo sapiens
125 RSL24D1  
Affinity Capture-MS Homo sapiens
126 ARL6IP5 10550
Proximity Label-MS Homo sapiens
127 BTF3 689
Affinity Capture-MS Homo sapiens
128 ADRB2  
Affinity Capture-MS Homo sapiens
129 G3BP1 10146
Co-fractionation Homo sapiens
130 SRPR 6734
Proximity Label-MS Homo sapiens
131 SMPD4 55627
Proximity Label-MS Homo sapiens
132 CCT6B 10693
Affinity Capture-MS Homo sapiens
133 NUP160 23279
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 DNAJB6 10049
Proximity Label-MS Homo sapiens
135 MBIP  
Two-hybrid Homo sapiens
136 RNPS1 10921
Affinity Capture-MS Homo sapiens
137 REEP2  
Affinity Capture-MS Homo sapiens
138 ELOVL2  
Proximity Label-MS Homo sapiens
139 PRC1 9055
Affinity Capture-MS Homo sapiens
140 NPM1 4869
Affinity Capture-MS Homo sapiens
141 ACTR1A 10121
Co-fractionation Homo sapiens
142 NUP93 9688
Affinity Capture-MS Homo sapiens
143 OBSL1 23363
Affinity Capture-MS Homo sapiens
144 SUN2 25777
Proximity Label-MS Homo sapiens
145 VCAM1 7412
Affinity Capture-MS Homo sapiens
146 USP7 7874
Proximity Label-MS Homo sapiens
147 FANCD2  
Affinity Capture-MS Homo sapiens
148 PES1 23481
Affinity Capture-MS Homo sapiens
149 LMAN1 3998
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
150 KIAA1715 80856
Proximity Label-MS Homo sapiens
151 UFL1 23376
Proximity Label-MS Homo sapiens
152 NAE1 8883
Co-fractionation Homo sapiens
153 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 DDX21 9188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
155 ATF4  
Two-hybrid Homo sapiens
156 SNRNP200 23020
Affinity Capture-MS Homo sapiens
157 VRK1 7443
Proximity Label-MS Homo sapiens
158 CDKAL1  
Proximity Label-MS Homo sapiens
159 DDX10  
Affinity Capture-MS Homo sapiens
160 SNRPD1 6632
Co-fractionation Homo sapiens
161 NAT10 55226
Affinity Capture-MS Homo sapiens
162 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
163 PREB 10113
Proximity Label-MS Homo sapiens
164 RNF13 11342
Co-purification Homo sapiens
165 STX5 6811
Proximity Label-MS Homo sapiens
166 MAGOH 4116
Affinity Capture-MS Homo sapiens
167 ACTR10 55860
Co-fractionation Homo sapiens
168 EGF 1950
Affinity Capture-Western Homo sapiens
169 UTP20 27340
Affinity Capture-MS Homo sapiens
170 PPAN-P2RY11  
Proximity Label-MS Homo sapiens
171 RPN2 6185
Proximity Label-MS Homo sapiens
172 CANX 821
Proximity Label-MS Homo sapiens
173 SMARCAD1  
Affinity Capture-MS Homo sapiens
174 XPO1 7514
Proximity Label-MS Homo sapiens
175 EIF6 3692
Co-fractionation Homo sapiens
176 UBXN7 26043
Proximity Label-MS Homo sapiens
177 C1orf52  
Proximity Label-MS Homo sapiens
178 TNPO3 23534
Proximity Label-MS Homo sapiens
179 DMAP1 55929
Two-hybrid Homo sapiens
180 PIAS1 8554
Proximity Label-MS Homo sapiens
181 HMGB3 3149
Proximity Label-MS Homo sapiens
182 NIPBL 25836
Affinity Capture-MS Homo sapiens
183 VRK2 7444
Proximity Label-MS Homo sapiens
184 SNW1 22938
Affinity Capture-MS Homo sapiens
185 DDRGK1 65992
Proximity Label-MS Homo sapiens
186 TMEM209 84928
Proximity Label-MS Homo sapiens
187 LEMD3  
Proximity Label-MS Homo sapiens
188 MCM3AP  
Proximity Label-MS Homo sapiens
189 EIF3H 8667
Affinity Capture-MS Homo sapiens
190 SUN1 23353
Proximity Label-MS Homo sapiens
191 PARP1 142
Proximity Label-MS Homo sapiens
192 ILF3 3609
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
193 TP53 7157
Affinity Capture-MS Homo sapiens
194 PGRMC1 10857
Proximity Label-MS Homo sapiens
195 TMEM214 54867
Proximity Label-MS Homo sapiens
196 ACTR1B 10120
Co-fractionation Homo sapiens
197 CMTR1 23070
Proximity Label-MS Homo sapiens
198 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
199 CDK1 983
Biochemical Activity Homo sapiens
200 POU2F1 5451
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
201 ESR1  
Affinity Capture-MS Homo sapiens
202 AUP1 550
Proximity Label-MS Homo sapiens
203 DDX39A 10212
Co-fractionation Homo sapiens
204 SPAG7  
Proximity Label-MS Homo sapiens
205 CLCN7 1186
Proximity Label-MS Homo sapiens
206 CXorf56  
Proximity Label-MS Homo sapiens
207 TMEM109 79073
Proximity Label-MS Homo sapiens
208 YKT6 10652
Proximity Label-MS Homo sapiens
209 IGF2R 3482
Proximity Label-MS Homo sapiens
210 M1AP  
Two-hybrid Homo sapiens
211 C1QBP 708
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
212 HSPA4L 22824
Co-fractionation Homo sapiens
213 CKAP4 10970
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
214 RCOR1  
Co-fractionation Homo sapiens
215 RANBP2 5903
Affinity Capture-MS Homo sapiens
216 ATAD1 84896
Affinity Capture-MS Homo sapiens
217 RALY 22913
Affinity Capture-MS Homo sapiens
218 NOP14 8602
Affinity Capture-MS Homo sapiens
219 PPP3CA 5530
Co-fractionation Homo sapiens
220 CCDC88B 283234
Two-hybrid Homo sapiens
221 NOP58 51602
Affinity Capture-MS Homo sapiens
222 NDUFS1 4719
Affinity Capture-MS Homo sapiens
223 MARCKS 4082
Proximity Label-MS Homo sapiens
224 USP48  
Co-fractionation Homo sapiens
225 YWHAE 7531
Co-fractionation Homo sapiens
226 SSB 6741
Co-fractionation Homo sapiens
227 LRRC59 55379
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
228 PTPN1 5770
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
229 STX4 6810
Proximity Label-MS Homo sapiens
230 PCGF2 7703
Affinity Capture-Western Homo sapiens
231 NDUFB9 4715
Affinity Capture-MS Homo sapiens
232 TEX264 51368
Proximity Label-MS Homo sapiens
233 TRIM28 10155
Co-fractionation Homo sapiens
234 Atm  
Affinity Capture-MS Mus musculus
235 MCM2 4171
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
236 KLC2 64837
Co-fractionation Homo sapiens
237 SENP1  
Proximity Label-MS Homo sapiens
238 RAB3B 5865
Proximity Label-MS Homo sapiens
239 IQGAP1 8826
Co-fractionation Homo sapiens
240 PPP1R7 5510
Co-fractionation Homo sapiens
241 LSG1  
Proximity Label-MS Homo sapiens
242 SSR1 6745
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
243 MCM6 4175
Co-fractionation Homo sapiens
244 LSM2 57819
Co-fractionation Homo sapiens
245 FAM136A 84908
Affinity Capture-MS Homo sapiens
246 HMGA2 8091
Proximity Label-MS Homo sapiens
247 RCC1 1104
Affinity Capture-MS Homo sapiens
248 ITGA4 3676
Affinity Capture-MS Homo sapiens
249 ATRX 546
Affinity Capture-MS Homo sapiens
250 CCDC47 57003
Proximity Label-MS Homo sapiens
251 DDX18 8886
Affinity Capture-MS Homo sapiens
252 ATG16L1 55054
Affinity Capture-MS Homo sapiens
253 MXRA7 439921
Proximity Label-MS Homo sapiens
254 TFCP2 7024
Affinity Capture-MS Homo sapiens
255 NCSTN 23385
Co-fractionation Homo sapiens
256 RBM8A 9939
Affinity Capture-MS Homo sapiens
257 HSPA8 3312
Co-fractionation Homo sapiens
258 DHRS7 51635
Proximity Label-MS Homo sapiens
259 NUP155 9631
Proximity Label-MS Homo sapiens
260 PXMP2  
Proximity Label-MS Homo sapiens
261 SCFD1 23256
Proximity Label-MS Homo sapiens
262 FOXC1  
Affinity Capture-MS Homo sapiens
263 LMNA 4000
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 PINX1  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
265 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 CXADR 1525
Proximity Label-MS Homo sapiens
267 CHCHD3 54927
Affinity Capture-MS Homo sapiens
268 PPIL4  
Proximity Label-MS Homo sapiens
269 RAB4A 5867
Proximity Label-MS Homo sapiens
270 NOP2 4839
Affinity Capture-MS Homo sapiens
271 KPNA4 3840
Co-fractionation Homo sapiens
272 PPIL2  
Proximity Label-MS Homo sapiens
273 CHMP4B 128866
Affinity Capture-MS Homo sapiens
274 RPA2 6118
Proximity Label-MS Homo sapiens
275 DIRAS3  
Proximity Label-MS Homo sapiens
276 RAN 5901
Affinity Capture-MS Homo sapiens
277 NTRK1 4914
Affinity Capture-MS Homo sapiens
278 LAS1L 81887
Affinity Capture-MS Homo sapiens
279 CCDC8  
Affinity Capture-MS Homo sapiens
280 MTPAP 55149
Proximity Label-MS Homo sapiens
281 RPN1 6184
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
282 GNAI2 2771
Affinity Capture-MS Homo sapiens
283 TECR 9524
Proximity Label-MS Homo sapiens
284 KPNA5 3841
Two-hybrid Homo sapiens
285 C1orf131  
Affinity Capture-MS Homo sapiens
286 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
287 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
288 RPS29 6235
Affinity Capture-MS Homo sapiens
289 DCTN3 11258
Co-fractionation Homo sapiens
290 ZBTB2 57621
Affinity Capture-MS Homo sapiens
291 METTL14  
Affinity Capture-MS Homo sapiens
292 TRIM33 51592
Co-fractionation Homo sapiens
293 LMNB2 84823
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
294 EPPK1 83481
Proximity Label-MS Homo sapiens
295 HSD3B7 80270
Proximity Label-MS Homo sapiens
296 S100A7 6278
Affinity Capture-MS Homo sapiens
297 STIM1 6786
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
298 POM121  
Proximity Label-MS Homo sapiens
299 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
300 DHX30 22907
Proximity Label-MS Homo sapiens
301 OCIAD1 54940
Proximity Label-MS Homo sapiens
302 SOX15  
Co-fractionation Homo sapiens
303 PDCD4 27250
Co-fractionation Homo sapiens
304 NCAPH 23397
Co-fractionation Homo sapiens
305 ZC3H18  
Affinity Capture-MS Homo sapiens
306 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
307 RAB9A 9367
Proximity Label-MS Homo sapiens
308 NHP2L1 4809
Affinity Capture-MS Homo sapiens
309 HP1BP3 50809
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
310 ACTB 60
Co-fractionation Homo sapiens
311 RANBP1 5902
Affinity Capture-MS Homo sapiens
312 LRRC41 10489
Proximity Label-MS Homo sapiens
313 MAGT1 84061
Co-fractionation Homo sapiens
314 UBXN4 23190
Proximity Label-MS Homo sapiens
315 UBE2J1 51465
Proximity Label-MS Homo sapiens
316 MBOAT7 79143
Proximity Label-MS Homo sapiens
317 DDX50 79009
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
318 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
319 PHB2 11331
Affinity Capture-MS Homo sapiens
320 ALDH3A2 224
Proximity Label-MS Homo sapiens
321 GPR89A  
Proximity Label-MS Homo sapiens
322 NUP205 23165
Proximity Label-MS Homo sapiens
323 JUP 3728
Co-fractionation Homo sapiens
324 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
325 CWC27 10283
Proximity Label-MS Homo sapiens
326 NMI  
Co-fractionation Homo sapiens
327 MCM5 4174
Co-fractionation Homo sapiens
328 RPA1 6117
Co-fractionation Homo sapiens
329 ALDH1B1 219
Affinity Capture-MS Homo sapiens
330 ZZEF1 23140
Co-fractionation Homo sapiens
331 PDHA1 5160
Affinity Capture-MS Homo sapiens
332 HNRNPM 4670
Co-fractionation Homo sapiens
333 SEPT10 151011
Proximity Label-MS Homo sapiens
334 THRAP3 9967
Affinity Capture-MS Homo sapiens
335 SNAPIN 23557
Two-hybrid Homo sapiens
336 ERGIC1 57222
Proximity Label-MS Homo sapiens
337 DHX40  
Proximity Label-MS Homo sapiens
338 API5 8539
Co-fractionation Homo sapiens
339 GTPBP4 23560
Affinity Capture-MS Homo sapiens
340 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
341 SPG20 23111
Affinity Capture-MS Homo sapiens
342 AGPAT6 137964
Proximity Label-MS Homo sapiens
343 SERBP1 26135
Affinity Capture-MS Homo sapiens
344 STT3B 201595
Proximity Label-MS Homo sapiens
345 CLPTM1L 81037
Proximity Label-MS Homo sapiens
346 UHRF1 29128
Proximity Label-MS Homo sapiens
347 AR 367
Affinity Capture-MS Homo sapiens
348 RAC1 5879
Affinity Capture-MS Homo sapiens
349 PRKCB 5579
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
350 VIM 7431
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
351 CDK11A 728642
Affinity Capture-MS Homo sapiens
352 SPCS2 9789
Proximity Label-MS Homo sapiens
353 UBE2H 7328
Affinity Capture-MS Homo sapiens
354 SLFN11 91607
Affinity Capture-MS Homo sapiens
355 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
356 HSD17B11 51170
Proximity Label-MS Homo sapiens
357 MCM8 84515
Affinity Capture-MS Homo sapiens
358 Lmna 16905
Affinity Capture-MS Mus musculus
359 SCARNA22  
Affinity Capture-RNA Homo sapiens
360 VAPA 9218
Proximity Label-MS Homo sapiens
361 BCLAF1 9774
Affinity Capture-MS Homo sapiens
362 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
363 GIT2 9815
Two-hybrid Homo sapiens
364 KPNB1 3837
Affinity Capture-MS Homo sapiens
365 ZC3H14  
Affinity Capture-MS Homo sapiens
366 THOC2 57187
Affinity Capture-MS Homo sapiens
367 USP9X 8239
Proximity Label-MS Homo sapiens
368 LAMP2 3920
Proximity Label-MS Homo sapiens
369 DNAJC25 548645
Proximity Label-MS Homo sapiens
370 DHX57 90957
Proximity Label-MS Homo sapiens
371 AQR 9716
Affinity Capture-MS Homo sapiens
372 USP36  
Affinity Capture-MS Homo sapiens
373 KIAA1429 25962
Affinity Capture-MS Homo sapiens
374 B3GAT1  
Proximity Label-MS Homo sapiens
375 TBL1XR1 79718
Co-fractionation Homo sapiens
376 ISY1 57461
Affinity Capture-MS Homo sapiens
377 STIM2 57620
Proximity Label-MS Homo sapiens
378 POLR2I 5438
Affinity Capture-MS Homo sapiens
379 MDH1 4190
Affinity Capture-MS Homo sapiens
380 ZNF512B  
Proximity Label-MS Homo sapiens
381 H2AFY2 55506
Affinity Capture-MS Homo sapiens
382 HMGA1 3159
Proximity Label-MS Homo sapiens
383 ABCE1 6059
Affinity Capture-MS Homo sapiens
384 Ncstn 59287
Affinity Capture-MS Mus musculus
385 RAD51  
Co-fractionation Homo sapiens
386 PGRMC2 10424
Proximity Label-MS Homo sapiens
387 DNAJC16  
Proximity Label-MS Homo sapiens
388 EED  
Affinity Capture-MS Homo sapiens
389 RRP8  
Affinity Capture-MS Homo sapiens
390 WDR18 57418
Affinity Capture-MS Homo sapiens
391 RAB35 11021
Proximity Label-MS Homo sapiens
392 MYCN  
Affinity Capture-MS Homo sapiens
393 FAF2 23197
Proximity Label-MS Homo sapiens
394 TMEM63B 55362
Affinity Capture-MS Homo sapiens
395 RB1 5925
Co-fractionation Homo sapiens
396 H2AFZ 3015
Proximity Label-MS Homo sapiens
397 LMNB1 4001
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
398 CENPH  
Two-hybrid Homo sapiens
399 COX15 1355
Affinity Capture-MS Homo sapiens
400 EMD 2010
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
401 AGK 55750
Affinity Capture-MS Homo sapiens
402 STAU1 6780
Affinity Capture-MS Homo sapiens
403 APOBEC3C 27350
Affinity Capture-MS Homo sapiens
404 SRSF6 6431
Co-fractionation Homo sapiens
405 BZLF1  
Affinity Capture-MS
406 SRRM2 23524
Affinity Capture-MS Homo sapiens
407 UBE2I 7329
Two-hybrid Homo sapiens
408 GCC2 9648
Affinity Capture-MS Homo sapiens
409 SMARCA4 6597
Co-fractionation Homo sapiens
410 PIAS2  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
411 OPA1 4976
Proximity Label-MS Homo sapiens
412 SF3B6 51639
Affinity Capture-MS Homo sapiens
413 DDX54 79039
Proximity Label-MS Homo sapiens
414 PML 5371
Proximity Label-MS Homo sapiens
415 SUDS3  
Affinity Capture-MS Homo sapiens
416 RAD54L2  
Proximity Label-MS Homo sapiens
417 SERPINA3 12
Two-hybrid Homo sapiens
418 ELOVL5 60481
Proximity Label-MS Homo sapiens
419 SLC33A1 9197
Proximity Label-MS Homo sapiens
420 USP10 9100
Affinity Capture-MS Homo sapiens
421 SMARCC2 6601
Co-fractionation Homo sapiens
422 RPF1  
Affinity Capture-MS Homo sapiens
423 SEC63 11231
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
424 PKMYT1  
Proximity Label-MS Homo sapiens
425 BMS1  
Affinity Capture-MS Homo sapiens
426 RXRA 6256
Affinity Capture-MS Homo sapiens
427 VAPB 9217
Proximity Label-MS Homo sapiens
428 CUL3 8452
Affinity Capture-MS Homo sapiens
429 PRKCA 5578
Reconstituted Complex Homo sapiens
430 PANX1 24145
Proximity Label-MS Homo sapiens
431 RNF169  
Proximity Label-MS Homo sapiens
432 HMOX2 3163
Proximity Label-MS Homo sapiens
433 CTNNB1 1499
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
434 RPL36A 6173
Affinity Capture-MS Homo sapiens
435 CCP110  
Affinity Capture-MS Homo sapiens
436 MCM4 4173
Co-fractionation Homo sapiens
437 BCCIP 56647
Co-fractionation Homo sapiens
438 PRKACA 5566
Affinity Capture-MS Homo sapiens
439 ACSL3 2181
Proximity Label-MS Homo sapiens
440 DKC1 1736
Affinity Capture-MS Homo sapiens
441 FBXO6 26270
Affinity Capture-MS Homo sapiens
442 NIN 51199
Proximity Label-MS Homo sapiens
443 SMARCB1 6598
Co-fractionation Homo sapiens
444 FNDC3A 22862
Proximity Label-MS Homo sapiens
445 SF3B3 23450
Co-fractionation Homo sapiens
446 VDAC1 7416
Affinity Capture-MS Homo sapiens
447 KRAS 3845
Proximity Label-MS Homo sapiens
448 DDX49 54555
Affinity Capture-MS Homo sapiens
449 RBM11  
Proximity Label-MS Homo sapiens
450 NIP7 51388
Affinity Capture-MS Homo sapiens
451 LBR 3930
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
452 UBE3B 89910
Affinity Capture-MS Homo sapiens
453 SPTAN1 6709
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
454 NUP133 55746
Proximity Label-MS Homo sapiens
455 ZRANB2 9406
Co-fractionation Homo sapiens
456 ERH 2079
Affinity Capture-MS Homo sapiens
457 WBP11  
Affinity Capture-MS Homo sapiens
458 SMARCC1 6599
Co-fractionation Homo sapiens
459 SAP18 10284
Affinity Capture-MS Homo sapiens
460 PIH1D2  
Two-hybrid Homo sapiens
461 YWHAB 7529
Co-fractionation Homo sapiens
462 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
463 HDAC1 3065
Co-fractionation Homo sapiens
464 CHD4 1108
Co-fractionation Homo sapiens
465 NSA2  
Affinity Capture-MS Homo sapiens
466 HDGF 3068
Co-fractionation Homo sapiens
467 NUP98 4928
Proximity Label-MS Homo sapiens
468 PDE6D 5147
Affinity Capture-MS Homo sapiens
469 SFXN1 94081
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
470 NUP50 10762
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
471 NUP107 57122
Proximity Label-MS Homo sapiens
472 MAGED1 9500
Affinity Capture-MS Homo sapiens
473 SEC62 7095
Proximity Label-MS Homo sapiens
474 AIRE  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
475 TRIM31  
Affinity Capture-MS Homo sapiens
476 PINK1  
Affinity Capture-MS Homo sapiens
477 CDK5RAP3 80279
Proximity Label-MS Homo sapiens
478 NDEL1 81565
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
479 DNAJC1 64215
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
480 HNRNPU 3192
Co-fractionation Homo sapiens
481 C9orf72  
Affinity Capture-MS Homo sapiens
482 RPA3 6119
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which LMNB1 is involved
PathwayEvidenceSource
Apoptosis TAS Reactome
Apoptotic cleavage of cellular proteins TAS Reactome
Apoptotic execution phase TAS Reactome
Breakdown of the nuclear lamina TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cellular Senescence TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Defective Intrinsic Pathway for Apoptosis IEA Reactome
Depolymerization of the Nuclear Lamina TAS Reactome
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models IEA Reactome
Disease IEA Reactome
Diseases of programmed cell death IEA Reactome
DNA Damage/Telomere Stress Induced Senescence TAS Reactome
Formation of Senescence-Associated Heterochromatin Foci (SAHF) TAS Reactome
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation TAS Reactome
Immune System TAS Reactome
Initiation of Nuclear Envelope (NE) Reformation TAS Reactome
Interleukin-12 family signaling TAS Reactome
Interleukin-12 signaling TAS Reactome
M Phase TAS Reactome
Meiosis IEA Reactome
Meiotic synapsis IEA Reactome
Mitotic Anaphase TAS Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Mitotic Prophase TAS Reactome
Neurodegenerative Diseases IEA Reactome
Nuclear Envelope (NE) Reassembly TAS Reactome
Nuclear Envelope Breakdown TAS Reactome
Programmed Cell Death TAS Reactome
Reproduction IEA Reactome
RHO GTPase cycle TAS Reactome
RHOD GTPase cycle TAS Reactome
RHOF GTPase cycle TAS Reactome
Signal Transduction TAS Reactome
Signaling by Interleukins TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome





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