Gene description for NUP93
Gene name nucleoporin 93kDa
Gene symbol NUP93
Other names/aliases NIC96
Species Homo sapiens
 Database cross references - NUP93
ExoCarta ExoCarta_9688
Entrez Gene 9688
HGNC 28958
MIM 614351
UniProt Q8N1F7  
 NUP93 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NUP93
Molecular Function
    structural constituent of nuclear pore GO:0017056 IMP
Biological Process
    glucose transport GO:0015758 TAS
    viral transcription GO:0019083 TAS
    carbohydrate metabolic process GO:0005975 TAS
    gene expression GO:0010467 TAS
    viral process GO:0016032 TAS
    viral life cycle GO:0019058 TAS
    cytokine-mediated signaling pathway GO:0019221 TAS
    regulation of glucose transport GO:0010827 TAS
    post-translational protein modification GO:0043687 TAS
    small molecule metabolic process GO:0044281 TAS
    protein import into nucleus GO:0006606 IBA
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 IMP
    cellular response to heat GO:0034605 TAS
    mitotic nuclear envelope disassembly GO:0007077 TAS
    positive regulation of defense response to virus by host GO:0002230 IMP
    regulation of cellular response to heat GO:1900034 TAS
    protein sumoylation GO:0016925 TAS
    nuclear pore complex assembly GO:0051292 IMP
    transmembrane transport GO:0055085 TAS
    mitotic cell cycle GO:0000278 TAS
    hexose transport GO:0008645 TAS
    cellular protein metabolic process GO:0044267 TAS
    poly(A)+ mRNA export from nucleus GO:0016973 IBA
Subcellular Localization
    nuclear periphery GO:0034399 IDA
    nuclear pore GO:0005643 IDA
    nuclear membrane GO:0031965 IDA
    membrane GO:0016020 IDA
    nuclear envelope GO:0005635 TAS
 Experiment description of studies that identified NUP93 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NUP93
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CASP4  
Affinity Capture-MS Homo sapiens
2 BRF2  
Affinity Capture-MS Homo sapiens
3 PHLDA3  
Affinity Capture-MS Homo sapiens
4 PHB2 11331
Affinity Capture-MS Homo sapiens
5 GIPC1 10755
Affinity Capture-MS Homo sapiens
6 TPR 7175
Affinity Capture-Western Homo sapiens
7 MYC  
Affinity Capture-MS Homo sapiens
8 PNKP 11284
Affinity Capture-MS Homo sapiens
9 NEK6 10783
Affinity Capture-MS Homo sapiens
10 TSC22D1  
Affinity Capture-MS Homo sapiens
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