Gene description for SLFN11
Gene name schlafen family member 11
Gene symbol SLFN11
Other names/aliases SLFN8/9
Species Homo sapiens
 Database cross references - SLFN11
ExoCarta ExoCarta_91607
Entrez Gene 91607
HGNC 26633
MIM 614953
UniProt Q7Z7L1  
 SLFN11 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SLFN11
Molecular Function
    tRNA binding GO:0000049 IDA
    ATP binding GO:0005524 IEA
Biological Process
    negative regulation of G1/S transition of mitotic cell cycle GO:2000134 IMP
    defense response to virus GO:0051607 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
    aggresome GO:0016235 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified SLFN11 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLFN11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLFN11 is involved
No pathways found





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