Experiment description of studies that identified SYNM in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for SYNM

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NES 10763 Affinity Capture-MS Homo sapiens 2 RNF43   Proximity Label-MS Homo sapiens 3 DTNA   Reconstituted Complex Homo sapiens 4 PPP2R2B 5521 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 5 SLFN11 91607 Affinity Capture-MS Homo sapiens 6 GRB2 2885 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 7 KIF14 9928 Affinity Capture-MS Homo sapiens 8 CBL 867 Affinity Capture-Western Homo sapiens 9 CSNK2A2 1459 Affinity Capture-MS Homo sapiens 10 KRT8 3856 Proximity Label-MS Homo sapiens 11 PHLPP1   Proximity Label-MS Homo sapiens 12 PRKAR2A 5576 Affinity Capture-Western Homo sapiens 13 GFAP 2670 Proximity Label-MS Homo sapiens 14 PRPH 5630 Proximity Label-MS Homo sapiens 15 DES 1674 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 16 STIM1 6786 Proximity Label-MS Homo sapiens 17 EMD 2010 Proximity Label-MS Homo sapiens 18 FKBP8 23770 Proximity Label-MS Homo sapiens 19 Bach1 12013 Affinity Capture-MS Mus musculus 20 Tuba3a 22144 Affinity Capture-MS Mus musculus 21 AMPH 273 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 22 TRIM37   Proximity Label-MS Homo sapiens 23 B3GNT2 10678 Affinity Capture-MS Homo sapiens 24 PPP2R1A 5518 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 25 SKA1   Affinity Capture-MS Homo sapiens 26 DNAJB4 11080 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 CEP135   Proximity Label-MS Homo sapiens 28 SYNC   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 COPS6 10980 Affinity Capture-MS Homo sapiens 30 CUL4A 8451 Affinity Capture-MS Homo sapiens 31 CT55   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 DNAJC1 64215 Proximity Label-MS Homo sapiens 33 PIK3R1 5295 Affinity Capture-Western Homo sapiens 34 MYC   Affinity Capture-MS Homo sapiens 35 KRT19 3880 Proximity Label-MS Homo sapiens 36 SH3GL2   Affinity Capture-Western Homo sapiens 37 PACSIN1   Affinity Capture-Western Homo sapiens 38 FGFR1OP   Affinity Capture-MS Homo sapiens 39 EP300 2033 Affinity Capture-MS Homo sapiens View the network

Pathways in which SYNM is involved

No pathways found