Gene description for PRPH
Gene name peripherin
Gene symbol PRPH
Other names/aliases NEF4
Species Homo sapiens
 Database cross references - PRPH
ExoCarta ExoCarta_5630
Entrez Gene 5630
HGNC 9461
MIM 170710
UniProt P41219  
 PRPH identified in exosomes derived from the following tissue/cell type
Liver cancer cells 25265333    
 Gene ontology annotations for PRPH
Molecular Function
    structural molecule activity GO:0005198 IEA
Biological Process
    intermediate filament cytoskeleton organization GO:0045104 IEA
Subcellular Localization
    neurofilament GO:0005883 IEA
    type III intermediate filament GO:0045098 IEA
    membrane GO:0016020 IDA
    photoreceptor outer segment membrane GO:0042622 IEA
    C-fiber GO:0044299 IEA
    intermediate filament GO:0005882 TAS
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified PRPH in exosomes
Experiment ID 267
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh‑7 Cells Using SILAC Labeling and LC−MS/MS
Authors Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx plasmids
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for PRPH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRT15 3866
Two-hybrid Homo sapiens
2 LMNB1 4001
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PRPH is involved
No pathways found

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