Gene description for OCRL
Gene name	oculocerebrorenal syndrome of Lowe
Gene symbol	OCRL
Other names/aliases	INPP5F LOCR NPHL2 OCRL-1 OCRL1
Species	Homo sapiens
Database cross references - OCRL
ExoCarta	ExoCarta_4952
Entrez Gene	4952
HGNC	8108
MIM	300535
UniProt	Q01968
OCRL identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for OCRL

Molecular Function     inositol phosphate phosphatase activity GO:0052745 NAS     GTPase activator activity GO:0005096 IDA     phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GO:0004439 IEA     Rac GTPase binding GO:0048365 IPI     protein binding GO:0005515 IPI Biological Process     regulation of GTPase activity GO:0043087 IDA     lipid metabolic process GO:0006629 NAS     phosphatidylinositol dephosphorylation GO:0046856 IEA     cilium assembly GO:0042384 IMP     inositol phosphate metabolic process GO:0043647 TAS     phosphatidylinositol biosynthetic process GO:0006661 TAS     in utero embryonic development GO:0001701 IEA     phospholipid metabolic process GO:0006644 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     small GTPase mediated signal transduction GO:0007264 TAS     positive regulation of GTPase activity GO:0043547 IDA     small molecule metabolic process GO:0044281 TAS Subcellular Localization     photoreceptor outer segment GO:0001750 IDA     extracellular exosome GO:0070062 IDA     Golgi stack GO:0005795 TAS     trans-Golgi network GO:0005802 IDA     phagocytic vesicle membrane GO:0030670 IEA     Golgi-associated vesicle GO:0005798 TAS     plasma membrane GO:0005886 IDA     cytosol GO:0005829 TAS     clathrin-coated vesicle GO:0030136 IDA     nucleus GO:0005634 IDA     cytoplasm GO:0005737 IDA     early endosome membrane GO:0031901 IEA     coated pit GO:0005905 IEA     early endosome GO:0005769 IDA