Gene description for LPP
Gene name LIM domain containing preferred translocation partner in lipoma
Gene symbol LPP
Other names/aliases -
Species Homo sapiens
 Database cross references - LPP
ExoCarta ExoCarta_4026
Entrez Gene 4026
HGNC 6679
MIM 600700
UniProt Q93052  
 LPP identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for LPP
Molecular Function
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
Biological Process
    biological_process GO:0008150 ND
    cell adhesion GO:0007155 IEA
Subcellular Localization
    focal adhesion GO:0005925 IDA
    cytoplasm GO:0005737 IDA
    plasma membrane GO:0005886 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified LPP in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LPP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VASP 7408
Invivo Homo sapiens
Invitro Homo sapiens
2 ATP5J2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which LPP is involved
No pathways found





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