Gene description for HSPA5
Gene name heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Gene symbol HSPA5
Other names/aliases BIP
GRP78
HEL-S-89n
MIF2
Species Homo sapiens
 Database cross references - HSPA5
ExoCarta ExoCarta_3309
Vesiclepedia VP_3309
Entrez Gene 3309
HGNC 5238
MIM 138120
UniProt P11021  
 HSPA5 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 19415654    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Liver cancer cells 25265333    
Liver cancer cells 25265333    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 25857301    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 15326289    
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for HSPA5
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    calcium ion binding GO:0005509 TAS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    ATP hydrolysis activity GO:0016887 IBA
    ATP hydrolysis activity GO:0016887 IDA
    ATP hydrolysis activity GO:0016887 ISS
    enzyme binding GO:0019899 IPI
    protein domain specific binding GO:0019904 IPI
    protein serine/threonine kinase inhibitor activity GO:0030291 IDA
    heat shock protein binding GO:0031072 IBA
    ubiquitin protein ligase binding GO:0031625 IPI
    ribosome binding GO:0043022 IEA
    protein folding chaperone GO:0044183 IBA
    cadherin binding GO:0045296 HDA
    unfolded protein binding GO:0051082 TAS
    protein-folding chaperone binding GO:0051087 TAS
    misfolded protein binding GO:0051787 IDA
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent protein folding chaperone GO:0140662 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    ER overload response GO:0006983 IEA
    cerebellum structural organization GO:0021589 IEA
    cerebellar Purkinje cell layer development GO:0021680 IEA
    substantia nigra development GO:0021762 HEP
    positive regulation of cell migration GO:0030335 IMP
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IEA
    endoplasmic reticulum unfolded protein response GO:0030968 IBA
    endoplasmic reticulum unfolded protein response GO:0030968 TAS
    post-translational protein targeting to membrane, translocation GO:0031204 IMP
    negative regulation of protein-containing complex assembly GO:0031333 ISS
    positive regulation of protein ubiquitination GO:0031398 IEA
    protein folding in endoplasmic reticulum GO:0034975 TAS
    response to endoplasmic reticulum stress GO:0034976 TAS
    maintenance of protein localization in endoplasmic reticulum GO:0035437 IMP
    ERAD pathway GO:0036503 IBA
    ERAD pathway GO:0036503 TAS
    protein refolding GO:0042026 IBA
    cellular response to glucose starvation GO:0042149 IDA
    negative regulation of apoptotic process GO:0043066 IMP
    negative regulation of apoptotic process GO:0043066 TAS
    positive regulation of transcription by RNA polymerase II GO:0045944 TAS
    chaperone cofactor-dependent protein refolding GO:0051085 IBA
    regulation of protein folding in endoplasmic reticulum GO:0060904 TAS
    cellular response to interleukin-4 GO:0071353 IEA
    chromatin looping GO:0140588 IEA
    regulation of ATF6-mediated unfolded protein response GO:1903891 TAS
    regulation of IRE1-mediated unfolded protein response GO:1903894 TAS
    negative regulation of IRE1-mediated unfolded protein response GO:1903895 ISS
    regulation of PERK-mediated unfolded protein response GO:1903897 TAS
    negative regulation of PERK-mediated unfolded protein response GO:1903898 IDA
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IMP
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum GO:0005783 IMP
    endoplasmic reticulum GO:0005783 TAS
    endoplasmic reticulum lumen GO:0005788 IBA
    endoplasmic reticulum lumen GO:0005788 IDA
    endoplasmic reticulum lumen GO:0005788 TAS
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 TAS
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IDA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IEA
    focal adhesion GO:0005925 HDA
    COP9 signalosome GO:0008180 IDA
    cell surface GO:0009986 IEA
    membrane GO:0016020 HDA
    membrane GO:0016020 IBA
    midbody GO:0030496 IDA
    protein-containing complex GO:0032991 IDA
    endoplasmic reticulum chaperone complex GO:0034663 IBA
    endoplasmic reticulum chaperone complex GO:0034663 IDA
    melanosome GO:0042470 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified HSPA5 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 65
MISEV standards
✘ Biophysical techniques
✔
HSP60|HSP27|GAPDH|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors "Staubach S, Razawi H, Hanisch FG."
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
10
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
19
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
23
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
24
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
25
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
26
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
27
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
33
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
38
Experiment ID 266
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Wild type
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 268
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx-null HBV replicon plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 200
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
49
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
50
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
52
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
55
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
56
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
57
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
58
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
59
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
60
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
61
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
62
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
63
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
64
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
65
Experiment ID 250
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|TSG101|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25857301    
Organism Homo sapiens
Experiment description Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles.
Authors "Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria PJ, Cavallini L, Ciardiello C, Reis Sobreiro M, Morello M, Kharmate G, Jang SC, Kim DK, Hosseini-Beheshti E, Tomlinson Guns E, Gleave M, Gho YS, Mathivanan S, Yang W, Freeman MR, Di Vizio D"
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - expressing DIAPH3 hRNA
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
66
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
67
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
68
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
69
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
70
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
71
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
72
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
73
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
74
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
75
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
76
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
77
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
78
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
79
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
80
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSPA5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BRINP2  
Affinity Capture-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 LCN12  
Affinity Capture-MS Homo sapiens
4 HDAC4  
Affinity Capture-MS Homo sapiens
5 WDR6 11180
Co-fractionation Homo sapiens
6 AGT 183
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 PABPC1 26986
Co-fractionation Homo sapiens
8 ZC3H13 23091
Co-fractionation Homo sapiens
9 SLFN11 91607
Affinity Capture-MS Homo sapiens
10 UBL4A 8266
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 SHC1 6464
Affinity Capture-MS Homo sapiens
12 MATK  
Reconstituted Complex Homo sapiens
13 GALC 2581
Affinity Capture-MS Homo sapiens
14 PAEP  
Affinity Capture-MS Homo sapiens
15 ERO1L 30001
Proximity Label-MS Homo sapiens
16 RIN3  
Affinity Capture-MS Homo sapiens
17 SH3BP4 23677
Two-hybrid Homo sapiens
18 DYNC1I2 1781
Co-fractionation Homo sapiens
19 GCNT1  
Affinity Capture-MS Homo sapiens
20 KIAA2013 90231
Affinity Capture-MS Homo sapiens
21 CRK 1398
Affinity Capture-MS Homo sapiens
22 NFATC1 4772
Affinity Capture-MS Homo sapiens
23 CAP1 10487
Co-fractionation Homo sapiens
24 DDX17 10521
Co-fractionation Homo sapiens
25 EBNA-LP  
Affinity Capture-MS
26 EMID1  
Affinity Capture-MS Homo sapiens
27 MAP4 4134
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
28 UBE3A 7337
Reconstituted Complex Homo sapiens
29 UBC 7316
Reconstituted Complex Homo sapiens
30 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
31 VHL  
Reconstituted Complex Homo sapiens
32 ACTB 60
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
33 SPAG4  
Affinity Capture-MS Homo sapiens
34 SEPT2 4735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 PRKDC 5591
Affinity Capture-MS Homo sapiens
36 OTUD3 23252
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
37 EFNA3  
Affinity Capture-MS Homo sapiens
38 TCN2 6948
Affinity Capture-MS Homo sapiens
39 LAMC1 3915
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
40 DDX23 9416
Co-fractionation Homo sapiens
41 PSMC5 5705
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
42 B4GALT4 8702
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 PFKL 5211
Co-fractionation Homo sapiens
44 KIF23 9493
Co-fractionation Homo sapiens
45 NDRG1 10397
Affinity Capture-MS Homo sapiens
46 PPP6C 5537
Affinity Capture-MS Homo sapiens
47 ACTR3 10096
Proximity Label-MS Homo sapiens
48 CLEC18A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 FCN3 8547
Affinity Capture-MS Homo sapiens
50 METTL22  
Affinity Capture-MS Homo sapiens
51 EGFL8  
Affinity Capture-MS Homo sapiens
52 GHRL  
Affinity Capture-MS Homo sapiens
53 SEL1L 6400
Affinity Capture-Western Homo sapiens
54 GLT8D2 83468
Affinity Capture-MS Homo sapiens
55 PSMD12 5718
Co-fractionation Homo sapiens
56 HSPH1 10808
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
57 GSR 2936
Proximity Label-MS Homo sapiens
58 INSIG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 PIK3C3 5289
Affinity Capture-MS Homo sapiens
60 MAGED2 10916
Affinity Capture-MS Homo sapiens
61 GSPT1 2935
Co-fractionation Homo sapiens
62 HELLS 3070
Affinity Capture-MS Homo sapiens
63 RCN2 5955
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
64 DYNLL1 8655
Co-fractionation Homo sapiens
65 SIRT3  
Affinity Capture-MS Homo sapiens
66 SNRPD3 6634
Co-fractionation Homo sapiens
67 UCHL5 51377
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
68 PPP4R4 57718
Affinity Capture-MS Homo sapiens
69 SFN 2810
Co-fractionation Homo sapiens
70 PNOC  
Affinity Capture-MS Homo sapiens
71 METTL18  
Affinity Capture-MS Homo sapiens
72 PRTN3 5657
Affinity Capture-MS Homo sapiens
73 PPP6R3 55291
Co-fractionation Homo sapiens
74 TSHB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 SYCN  
Affinity Capture-MS Homo sapiens
76 WDR5 11091
Co-fractionation Homo sapiens
77 LY6G6D  
Affinity Capture-MS Homo sapiens
78 FKBP10 60681
Proximity Label-MS Homo sapiens
79 SOD1 6647
Proximity Label-MS Homo sapiens
80 MSN 4478
Co-fractionation Homo sapiens
81 RBM14 10432
Affinity Capture-MS Homo sapiens
82 BAG6 7917
Affinity Capture-MS Homo sapiens
83 NOTCH2 4853
Affinity Capture-MS Homo sapiens
84 HAT1 8520
Co-fractionation Homo sapiens
85 UPK3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 TAZ  
Affinity Capture-MS Homo sapiens
87 TMEM25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 AURKA 6790
Affinity Capture-MS Homo sapiens
89 ANGPTL2 23452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 PTCD3 55037
Co-fractionation Homo sapiens
91 SEMA6C  
Affinity Capture-MS Homo sapiens
92 MTCH2 23788
Affinity Capture-MS Homo sapiens
93 NOMO1 23420
Proximity Label-MS Homo sapiens
94 SNRNP70 6625
Co-fractionation Homo sapiens
95 SPX  
Affinity Capture-MS Homo sapiens
96 UCN3  
Affinity Capture-MS Homo sapiens
97 SDF2 6388
Affinity Capture-MS Homo sapiens
98 CRY1  
Affinity Capture-MS Homo sapiens
99 USP11 8237
Affinity Capture-MS Homo sapiens
100 RAB14 51552
Co-fractionation Homo sapiens
101 SKI 6497
Affinity Capture-MS Homo sapiens
102 TRAFD1  
Affinity Capture-MS Homo sapiens
103 MEPCE 56257
Affinity Capture-MS Homo sapiens
104 CLU 1191
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
105 ITGAD  
Affinity Capture-MS Homo sapiens
106 SUPT5H 6829
Cross-Linking-MS (XL-MS) Homo sapiens
107 PSME1 5720
Co-fractionation Homo sapiens
108 SRSF3 6428
Co-fractionation Homo sapiens
109 KIAA1161 57462
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 SUDS3  
Co-fractionation Homo sapiens
111 TMTC3 160418
Proximity Label-MS Homo sapiens
112 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
113 TNFSF13 8741
Affinity Capture-MS Homo sapiens
114 MAGT1 84061
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 INSL3  
Affinity Capture-MS Homo sapiens
116 UBASH3B 84959
Affinity Capture-MS Homo sapiens
117 ESRRB  
Affinity Capture-MS Homo sapiens
118 KDELC2 143888
Affinity Capture-MS Homo sapiens
119 CDH1 999
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
120 MYDGF 56005
Affinity Capture-MS Homo sapiens
121 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 FIBIN  
Affinity Capture-MS Homo sapiens
123 R3HDML  
Affinity Capture-MS Homo sapiens
124 TRIM21 6737
Affinity Capture-MS Homo sapiens
125 CKAP5 9793
Affinity Capture-MS Homo sapiens
126 METTL21C  
Affinity Capture-MS Homo sapiens
127 GORASP2 26003
Affinity Capture-MS Homo sapiens
128 ALKBH3  
Affinity Capture-MS Homo sapiens
129 ITM2C 81618
Affinity Capture-MS Homo sapiens
130 DHH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 RPS10 6204
Cross-Linking-MS (XL-MS) Homo sapiens
132 NOS2  
Affinity Capture-MS Homo sapiens
133 P4HB 5034
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
134 Mapk13  
Affinity Capture-MS Mus musculus
135 ANKHD1 54882
Co-fractionation Homo sapiens
136 ADAMTS1 9510
Affinity Capture-MS Homo sapiens
137 VCL 7414
Co-fractionation Homo sapiens
138 CUL2 8453
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
139 CEP72  
Affinity Capture-MS Homo sapiens
140 DDX39B 7919
Affinity Capture-MS Homo sapiens
141 PICALM 8301
Affinity Capture-MS Homo sapiens
142 SEC61B 10952
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 HSPA4L 22824
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 ID2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
145 SPAG11A  
Affinity Capture-MS Homo sapiens
146 ARSA 410
Affinity Capture-MS Homo sapiens
147 RING1 6015
Co-fractionation Homo sapiens
148 TMPO 7112
Affinity Capture-MS Homo sapiens
149 WDR11 55717
Co-fractionation Homo sapiens
150 ADAMTS4  
Affinity Capture-MS Homo sapiens
151 HADHB 3032
Co-fractionation Homo sapiens
152 TTC13  
Proximity Label-MS Homo sapiens
153 CPOX 1371
Co-fractionation Homo sapiens
154 AHCYL1 10768
Co-fractionation Homo sapiens
155 IGHD  
Affinity Capture-MS Homo sapiens
156 APOE 348
Co-fractionation Homo sapiens
157 YBX1 4904
Co-fractionation Homo sapiens
158 IL25  
Affinity Capture-MS Homo sapiens
159 CHST8 64377
Affinity Capture-MS Homo sapiens
160 GGH 8836
Affinity Capture-MS Homo sapiens
161 PON2 5445
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 HS3ST2  
Affinity Capture-MS Homo sapiens
163 PRKCZ 5590
Affinity Capture-MS Homo sapiens
164 ERLEC1 27248
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
165 MTNR1A  
Affinity Capture-MS Homo sapiens
166 CSE1L 1434
Affinity Capture-MS Homo sapiens
167 DCPS 28960
Co-fractionation Homo sapiens
168 EGFL7 51162
Affinity Capture-MS Homo sapiens
169 ATP1B3 483
Affinity Capture-MS Homo sapiens
170 EPRS 2058
Co-fractionation Homo sapiens
171 LRRC32 2615
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 FAM187B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 TMEM263 90488
Affinity Capture-MS Homo sapiens
174 FN1 2335
Affinity Capture-MS Homo sapiens
175 SPCS3 60559
Affinity Capture-MS Homo sapiens
176 STRAP 11171
Co-fractionation Homo sapiens
177 TUBA4A 7277
Co-fractionation Homo sapiens
178 PRMT5 10419
Co-fractionation Homo sapiens
179 ITLN2  
Affinity Capture-MS Homo sapiens
180 CASP12 100506742
Affinity Capture-Western Homo sapiens
181 PCBP1 5093
Proximity Label-MS Homo sapiens
182 DDX5 1655
Co-fractionation Homo sapiens
183 CRTC3  
Affinity Capture-MS Homo sapiens
184 PLXNC1 10154
Affinity Capture-MS Homo sapiens
185 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
186 BCAN  
Affinity Capture-MS Homo sapiens
187 FCHSD2  
Two-hybrid Homo sapiens
188 CDC20 991
Affinity Capture-MS Homo sapiens
189 PIGZ  
Affinity Capture-MS Homo sapiens
190 TIGAR 57103
Proximity Label-MS Homo sapiens
191 HSPA1A 3303
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
192 HSPA4 3308
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
193 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
194 STMN1 3925
Affinity Capture-MS Homo sapiens
195 P3H3 10536
Affinity Capture-MS Homo sapiens
196 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
197 P4HA3 283208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 CSDE1 7812
Co-fractionation Homo sapiens
199 SCPEP1 59342
Co-fractionation Homo sapiens
200 AKT1 207
Affinity Capture-MS Homo sapiens
201 DLAT 1737
Cross-Linking-MS (XL-MS) Homo sapiens
202 NFATC2  
Affinity Capture-MS Homo sapiens
203 TRIB2 28951
Affinity Capture-MS Homo sapiens
204 NAAA  
Affinity Capture-MS Homo sapiens
205 SUPT16H 11198
Co-fractionation Homo sapiens
206 SCCPDH 51097
Co-fractionation Homo sapiens
207 COPS2 9318
Co-fractionation Homo sapiens
208 RPS16 6217
Co-fractionation Homo sapiens
209 STUB1 10273
Affinity Capture-MS Homo sapiens
210 INSL5  
Affinity Capture-MS Homo sapiens
211 METTL14  
Affinity Capture-MS Homo sapiens
212 OLFML2B 25903
Affinity Capture-MS Homo sapiens
213 RELA 5970
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 CPEB4  
Affinity Capture-MS Homo sapiens
215 NPTX1  
Affinity Capture-MS Homo sapiens
216 FASN 2194
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
217 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
218 MECP2 4204
Affinity Capture-MS Homo sapiens
219 GRB2 2885
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
220 USP25  
Affinity Capture-MS Homo sapiens
221 TROVE2 6738
Co-fractionation Homo sapiens
222 RNF40 9810
Affinity Capture-MS Homo sapiens
223 NMB  
Affinity Capture-MS Homo sapiens
224 ASIP  
Affinity Capture-MS Homo sapiens
225 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
226 TCERG1 10915
Affinity Capture-MS Homo sapiens
227 ZEB1  
Affinity Capture-MS Homo sapiens
228 EMC7 56851
Proximity Label-MS Homo sapiens
229 TMPRSS5  
Affinity Capture-MS Homo sapiens
230 POLR3H  
Affinity Capture-MS Homo sapiens
231 CDC37 11140
Affinity Capture-MS Homo sapiens
232 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
233 TMEM131  
Proximity Label-MS Homo sapiens
234 VSIG8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 MGAT5 4249
Affinity Capture-MS Homo sapiens
236 FKBP9 11328
Co-fractionation Homo sapiens
237 BMPR1A 657
Affinity Capture-MS Homo sapiens
238 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
239 OS9 10956
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 SIRT1  
Affinity Capture-MS Homo sapiens
241 LMAN1 3998
Proximity Label-MS Homo sapiens
242 SSBP1 6742
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
243 DYNC1H1 1778
Co-fractionation Homo sapiens
244 GLB1L3  
Affinity Capture-MS Homo sapiens
245 PWP1 11137
Affinity Capture-MS Homo sapiens
246 WWP2 11060
Affinity Capture-MS Homo sapiens
247 XPO5 57510
Affinity Capture-MS Homo sapiens
248 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
249 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
250 TPST1 8460
Affinity Capture-MS Homo sapiens
251 HNRNPL 3191
Co-fractionation Homo sapiens
252 PLD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
253 WDR76  
Affinity Capture-MS Homo sapiens
254 ZPBP2  
Affinity Capture-MS Homo sapiens
255 ASH2L 9070
Co-fractionation Homo sapiens
256 ARSI 340075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
257 RAB11A 8766
Co-fractionation Homo sapiens
258 HNRNPA1L2 144983
Affinity Capture-MS Homo sapiens
259 VIT  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
260 DHFRL1  
Affinity Capture-MS Homo sapiens
261 LDLR 3949
Affinity Capture-Western Homo sapiens
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
262 PRPF4 9128
Co-fractionation Homo sapiens
263 CUL7 9820
Affinity Capture-MS Homo sapiens
264 P2RX2  
Affinity Capture-MS Homo sapiens
265 TNFSF14  
Affinity Capture-MS Homo sapiens
266 PPP2R2A 5520
Co-fractionation Homo sapiens
267 PTCH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 GAPVD1 26130
Co-fractionation Homo sapiens
269 IRS4 8471
Cross-Linking-MS (XL-MS) Homo sapiens
270 PSMD3 5709
Co-fractionation Homo sapiens
271 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
272 PTPRF 5792
Two-hybrid Homo sapiens
273 PRSS2 5645
Affinity Capture-MS Homo sapiens
274 UGGT2 55757
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 LDHA 3939
Cross-Linking-MS (XL-MS) Homo sapiens
276 G0S2  
Affinity Capture-MS Homo sapiens
277 CLTC 1213
Co-fractionation Homo sapiens
278 LILRA5  
Affinity Capture-MS Homo sapiens
279 ERN1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
280 SPRTN  
Affinity Capture-MS Homo sapiens
281 SEP15 9403
Proximity Label-MS Homo sapiens
282 CNTNAP3  
Affinity Capture-MS Homo sapiens
283 HSPA6 3310
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
284 CD48 962
Affinity Capture-MS Homo sapiens
285 FBXL4 26235
Affinity Capture-MS Homo sapiens
286 KLK5 25818
Affinity Capture-MS Homo sapiens
287 PAWR 5074
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
288 MMP28  
Affinity Capture-MS Homo sapiens
289 TARDBP 23435
Affinity Capture-MS Homo sapiens
290 SCGB1D4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
291 RPA2 6118
Affinity Capture-MS Homo sapiens
292 VPRBP 9730
Co-fractionation Homo sapiens
293 LTBP2 4053
Affinity Capture-MS Homo sapiens
294 ADRB2  
Affinity Capture-MS Homo sapiens
295 APC  
Two-hybrid Homo sapiens
296 UCHL1 7345
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
297 NOP56 10528
Proximity Label-MS Homo sapiens
298 DTNA  
Affinity Capture-MS Homo sapiens
299 SURF4 6836
Co-fractionation Homo sapiens
300 LGALS1 3956
Co-fractionation Homo sapiens
301 TNFRSF6B  
Affinity Capture-MS Homo sapiens
302 HSP90AB1 3326
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
303 IGFALS 3483
Affinity Capture-MS Homo sapiens
304 CAND1 55832
Affinity Capture-MS Homo sapiens
305 B3GALT4  
Affinity Capture-MS Homo sapiens
306 SYVN1 84447
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
307 COPA 1314
Affinity Capture-MS Homo sapiens
308 KPNB1 3837
Co-fractionation Homo sapiens
309 CPT1A 1374
Two-hybrid Homo sapiens
310 PCDHA10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 KIAA1598 57698
Co-fractionation Homo sapiens
312 DNAJB6 10049
Affinity Capture-MS Homo sapiens
313 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
314 LRP1 4035
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 WTAP 9589
Affinity Capture-MS Homo sapiens
316 LUC7L2 51631
Co-fractionation Homo sapiens
317 GPS1 2873
Co-fractionation Homo sapiens
318 B3GNT2 10678
Affinity Capture-MS Homo sapiens
319 MFAP5  
Affinity Capture-MS Homo sapiens
320 TUBB 203068
Co-fractionation Homo sapiens
321 DDX24 57062
Two-hybrid Homo sapiens
322 COPS6 10980
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
323 PRDX2 7001
Co-fractionation Homo sapiens
324 SEC61A1 29927
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
325 B4GALT7 11285
Affinity Capture-MS Homo sapiens
326 INHA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
327 LEP  
Affinity Capture-MS Homo sapiens
328 NPM1 4869
Co-fractionation Homo sapiens
329 SRRM2 23524
Co-fractionation Homo sapiens
330 COPS8 10920
Co-fractionation Homo sapiens
331 WNT9B  
Affinity Capture-MS Homo sapiens
332 OBSL1 23363
Affinity Capture-MS Homo sapiens
333 FUCA2 2519
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
334 PLCG1 5335
Co-fractionation Homo sapiens
335 C1QC 714
Affinity Capture-MS Homo sapiens
336 STIP1 10963
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
337 NR4A1  
Affinity Capture-MS Homo sapiens
338 PLA2G12A  
Affinity Capture-MS Homo sapiens
339 CNPY2 10330
Proximity Label-MS Homo sapiens
340 DNAJC7 7266
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
341 PHB 5245
Co-fractionation Homo sapiens
342 TOR3A 64222
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
343 WFDC6  
Affinity Capture-MS Homo sapiens
344 PALLD 23022
Affinity Capture-MS Homo sapiens
345 CUL1 8454
Affinity Capture-MS Homo sapiens
346 SETD1A 9739
Co-fractionation Homo sapiens
347 KNSTRN  
Affinity Capture-MS Homo sapiens
348 GRIN3B  
Affinity Capture-MS Homo sapiens
349 RETN 56729
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
350 SFTPC  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
351 PRNP 5621
Reconstituted Complex Homo sapiens
352 ITLN1 55600
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
353 YWHAB 7529
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
354 CA11  
Affinity Capture-MS Homo sapiens
355 TG 7038
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
356 BSG 682
Co-fractionation Homo sapiens
357 BRINP1  
Affinity Capture-MS Homo sapiens
358 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
359 USP10 9100
Affinity Capture-MS Homo sapiens
360 C9orf40  
Cross-Linking-MS (XL-MS) Homo sapiens
361 LPP 4026
Co-fractionation Homo sapiens
362 C9orf78 51759
Affinity Capture-MS Homo sapiens
363 CDKN1A  
Affinity Capture-MS Homo sapiens
364 KLC1 3831
Co-fractionation Homo sapiens
365 AMFR 267
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
366 IGH 3492
Affinity Capture-MS Homo sapiens
367 NCOR2  
Affinity Capture-MS Homo sapiens
368 DNAH17 8632
Cross-Linking-MS (XL-MS) Homo sapiens
369 GDF15 9518
Affinity Capture-MS Homo sapiens
370 PSMD14 10213
Affinity Capture-MS Homo sapiens
371 CBL 867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
372 SNRNP200 23020
Co-fractionation Homo sapiens
373 SYPL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
374 NCKAP1 10787
Affinity Capture-MS Homo sapiens
375 UBR5 51366
Co-fractionation Homo sapiens
376 SNRPD1 6632
Co-fractionation Homo sapiens
377 NELFE 7936
Affinity Capture-MS Homo sapiens
378 ACP5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
379 PCDHGC4  
Affinity Capture-MS Homo sapiens
380 APOA2 336
Affinity Capture-MS Homo sapiens
381 CRISP2  
Affinity Capture-MS Homo sapiens
382 STK4 6789
Affinity Capture-MS Homo sapiens
383 TEPP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
384 WNT5A 7474
Affinity Capture-MS Homo sapiens
385 APOB 338
Affinity Capture-Western Homo sapiens
386 KRT14 3861
Two-hybrid Homo sapiens
387 CLEC11A 6320
Affinity Capture-MS Homo sapiens
388 LYPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
389 GNRH1  
Affinity Capture-MS Homo sapiens
390 PATE1  
Affinity Capture-MS Homo sapiens
391 FAM19A2 338811
Affinity Capture-MS Homo sapiens
392 PRKAR2A 5576
Co-fractionation Homo sapiens
393 GALNS 2588
Affinity Capture-MS Homo sapiens
394 COPS7B 64708
Co-fractionation Homo sapiens
395 SDF4 51150
Affinity Capture-MS Homo sapiens
396 ICAM4  
Affinity Capture-MS Homo sapiens
397 Ksr1  
Affinity Capture-MS Mus musculus
398 CYLD  
Affinity Capture-MS Homo sapiens
399 SEPT6 23157
Affinity Capture-MS Homo sapiens
400 EIF4B 1975
Co-fractionation Homo sapiens
401 NYX  
Affinity Capture-MS Homo sapiens
402 GRAMD1A  
Proximity Label-MS Homo sapiens
403 PCDHA8  
Affinity Capture-MS Homo sapiens
404 COLGALT1 79709
Proximity Label-MS Homo sapiens
405 HNRNPD 3184
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
406 PTPN11 5781
Reconstituted Complex Homo sapiens
407 CAMKMT  
Affinity Capture-MS Homo sapiens
408 COLEC11 78989
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
409 PSMA3 5684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
410 IL17B 27190
Affinity Capture-MS Homo sapiens
411 SEPT10 151011
Affinity Capture-MS Homo sapiens
412 COPS7A 50813
Co-fractionation Homo sapiens
413 RPN2 6185
Proximity Label-MS Homo sapiens
414 CANX 821
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
415 KCND3 3752
Affinity Capture-Western Homo sapiens
416 ICAM1 3383
Co-fractionation Homo sapiens
417 UGGT1 56886
Proximity Label-MS Homo sapiens
418 RC3H2  
Affinity Capture-MS Homo sapiens
419 IKZF3  
Affinity Capture-MS Homo sapiens
420 PSMC6 5706
Co-fractionation Homo sapiens
421 LAMB2 3913
Affinity Capture-MS Homo sapiens
422 TXNRD1 7296
Co-fractionation Homo sapiens
423 SNRPD2 6633
Co-fractionation Homo sapiens
424 CARM1 10498
Co-fractionation Homo sapiens
425 PDIA3 2923
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
426 METTL23  
Affinity Capture-MS Homo sapiens
427 ARIH2 10425
Affinity Capture-MS Homo sapiens
428 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
429 EMC1 23065
Proximity Label-MS Homo sapiens
430 TNFRSF18  
Affinity Capture-MS Homo sapiens
431 BCAP31 10134
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
432 PACSIN3 29763
Co-fractionation Homo sapiens
433 FUS 2521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
434 HSDL1 83693
Cross-Linking-MS (XL-MS) Homo sapiens
435 IKZF1  
Affinity Capture-MS Homo sapiens
436 GHITM 27069
Affinity Capture-MS Homo sapiens
437 SERPINB11  
Affinity Capture-MS Homo sapiens
438 N6AMT1 29104
Affinity Capture-MS Homo sapiens
439 SPTBN1 6711
Co-fractionation Homo sapiens
440 EFTUD2 9343
Co-fractionation Homo sapiens
441 CDK2 1017
Affinity Capture-MS Homo sapiens
442 CEP250 11190
Affinity Capture-MS Homo sapiens
443 EPHA8  
Affinity Capture-MS Homo sapiens
444 DNASE1L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
445 TRIM44  
Affinity Capture-MS Homo sapiens
446 TADA2A  
Affinity Capture-MS Homo sapiens
447 HHIPL1 84439
Affinity Capture-MS Homo sapiens
448 MYC  
Affinity Capture-MS Homo sapiens
449 CST11  
Affinity Capture-MS Homo sapiens
450 IL12RB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
451 ALDH3B2  
Affinity Capture-MS Homo sapiens
452 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
453 TMOD3 29766
Co-fractionation Homo sapiens
454 STT3B 201595
Proximity Label-MS Homo sapiens
455 COCH 1690
Affinity Capture-MS Homo sapiens
456 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
457 PRSS1 5644
Affinity Capture-MS Homo sapiens
458 DDB1 1642
Co-fractionation Homo sapiens
459 HNF1B  
Affinity Capture-MS Homo sapiens
460 DDRGK1 65992
Affinity Capture-MS Homo sapiens
461 MPPE1 65258
Affinity Capture-MS Homo sapiens
462 SERPING1 710
Affinity Capture-MS Homo sapiens
463 LOX 4015
Affinity Capture-MS Homo sapiens
464 ENTHD2  
Affinity Capture-MS Homo sapiens
465 WNT2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
466 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
467 CFB 629
Affinity Capture-MS Homo sapiens
468 AIMP1 9255
Co-fractionation Homo sapiens
469 EEF1A1 1915
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
470 LYZL2  
Affinity Capture-MS Homo sapiens
471 RNF43  
Proximity Label-MS Homo sapiens
472 TFG 10342
Affinity Capture-MS Homo sapiens
473 SFPQ 6421
Co-fractionation Homo sapiens
474 CA6 765
Affinity Capture-MS Homo sapiens
475 SPOP  
Affinity Capture-MS Homo sapiens
476 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
477 PARP1 142
Co-fractionation Homo sapiens
478 ILF3 3609
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
479 GPX7 2882
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
480 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
481 FOLR1 2348
Affinity Capture-MS Homo sapiens
482 IKBIP 121457
Proximity Label-MS Homo sapiens
483 CLASP2 23122
Affinity Capture-MS Homo sapiens
484 WNT10B 7480
Affinity Capture-MS Homo sapiens
485 SSRP1 6749
Co-fractionation Homo sapiens
486 CALU 813
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
487 HDAC6 10013
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
488 DNMT1 1786
Affinity Capture-MS Homo sapiens
489 PTBP1 5725
Co-fractionation Homo sapiens
490 SQSTM1 8878
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
491 RPL23 9349
Affinity Capture-MS Homo sapiens
492 B4GAT1 11041
Affinity Capture-MS Homo sapiens
493 MAGI3 260425
Cross-Linking-MS (XL-MS) Homo sapiens
494 MTNR1B  
Reconstituted Complex Homo sapiens
495 OTUB1 55611
Affinity Capture-MS Homo sapiens
496 SHMT2 6472
Affinity Capture-RNA Homo sapiens
497 TOR1B 27348
Affinity Capture-MS Homo sapiens
498 SPACA4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
499 ASAH1 427
Co-fractionation Homo sapiens
500 POU2F1 5451
Affinity Capture-MS Homo sapiens
501 MCFD2 90411
Affinity Capture-MS Homo sapiens
502 AAK1 22848
Affinity Capture-MS Homo sapiens
503 RPLP1 6176
Co-fractionation Homo sapiens
504 RNF38  
Affinity Capture-MS Homo sapiens
505 TSHR 7253
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
506 ADIPOQ 9370
Affinity Capture-MS Homo sapiens
507 TAGLN2 8407
Affinity Capture-MS Homo sapiens
508 DHX38 9785
Co-fractionation Homo sapiens
509 C16orf72 29035
Affinity Capture-MS Homo sapiens
510 YBX3 8531
Co-fractionation Homo sapiens
511 DNAJB4 11080
Affinity Capture-MS Homo sapiens
512 KIAA1217 56243
Cross-Linking-MS (XL-MS) Homo sapiens
513 DYNLRB1 83658
Cross-Linking-MS (XL-MS) Homo sapiens
514 NCEH1 57552
Affinity Capture-MS Homo sapiens
515 RPS6KC1  
Cross-Linking-MS (XL-MS) Homo sapiens
516 SIGLEC10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
517 KRAS 3845
Negative Genetic Homo sapiens
518 DNAJC3 5611
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
519 PSMD1 5707
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
520 CKAP4 10970
Proximity Label-MS Homo sapiens
521 PODN 127435
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
522 EIF2AK3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
523 PRMT1 3276
Affinity Capture-MS Homo sapiens
524 CTNNA1 1495
Affinity Capture-MS Homo sapiens
525 CUL4A 8451
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
526 STT3A 3703
Proximity Label-MS Homo sapiens
527 HMP19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
528 FCN1 2219
Affinity Capture-MS Homo sapiens
529 COPG2 26958
Cross-Linking-MS (XL-MS) Homo sapiens
530 ABCF3 55324
Affinity Capture-MS Homo sapiens
531 RPSA 3921
Co-fractionation Homo sapiens
532 C8A 731
Affinity Capture-MS Homo sapiens
533 C1QTNF3 114899
Affinity Capture-MS Homo sapiens
534 RAB1A 5861
Co-fractionation Homo sapiens
535 DNAJC8 22826
Co-fractionation Homo sapiens
536 ACOT7 11332
Co-fractionation Homo sapiens
537 NAPA 8775
Co-fractionation Homo sapiens
538 RIT1 6016
Negative Genetic Homo sapiens
539 TRIM7  
Affinity Capture-MS Homo sapiens
540 C1QTNF9  
Affinity Capture-MS Homo sapiens
541 DNAJA4 55466
Co-fractionation Homo sapiens
542 ABCF1 23
Cross-Linking-MS (XL-MS) Homo sapiens
543 IGHM 3507
Affinity Capture-MS Homo sapiens
544 EPS15 2060
Affinity Capture-MS Homo sapiens
545 UQCRB 7381
Co-fractionation Homo sapiens
546 SSB 6741
Co-fractionation Homo sapiens
547 GLB1L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
548 TMEM67 91147
Affinity Capture-Western Homo sapiens
549 HNRNPR 10236
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
550 LRRC59 55379
Proximity Label-MS Homo sapiens
551 SLURP1  
Affinity Capture-MS Homo sapiens
552 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
553 RPS6KB2  
Affinity Capture-MS Homo sapiens
554 TINAG  
Affinity Capture-MS Homo sapiens
555 ERO1LB 56605
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
556 TOR2A 27433
Affinity Capture-MS Homo sapiens
557 ANTXR1 84168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
558 LRPPRC 10128
Co-fractionation Homo sapiens
559 CELA3A  
Affinity Capture-MS Homo sapiens
560 CAPZB 832
Affinity Capture-MS Homo sapiens
561 HYAL1 3373
Affinity Capture-MS Homo sapiens
562 SERPINA1 5265
Affinity Capture-Western Homo sapiens
563 PLOD3 8985
Proximity Label-MS Homo sapiens
564 TPSB2  
Affinity Capture-MS Homo sapiens
565 BTLA  
Affinity Capture-MS Homo sapiens
566 MLLT4 4301
Cross-Linking-MS (XL-MS) Homo sapiens
567 HIST1H2BM 8342
Co-fractionation Homo sapiens
568 MAP1B 4131
Cross-Linking-MS (XL-MS) Homo sapiens
569 MCM2 4171
Affinity Capture-MS Homo sapiens
570 TSC22D2 9819
Cross-Linking-MS (XL-MS) Homo sapiens
571 HLA-B 3106
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
572 SPAG9 9043
Co-fractionation Homo sapiens
573 ING3  
Affinity Capture-MS Homo sapiens
574 CACNG7  
Affinity Capture-MS Homo sapiens
575 IQGAP1 8826
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
576 LGR4 55366
Affinity Capture-MS Homo sapiens
577 RBBP4 5928
Co-fractionation Homo sapiens
578 AHNAK2 113146
Cross-Linking-MS (XL-MS) Homo sapiens
579 BAGE2  
Affinity Capture-MS Homo sapiens
580 SSR1 6745
Affinity Capture-Western Homo sapiens
581 CHID1 66005
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
582 EWSR1 2130
Affinity Capture-MS Homo sapiens
583 PSMC2 5701
Co-fractionation Homo sapiens
584 CHST2 9435
Affinity Capture-MS Homo sapiens
585 RETNLB  
Affinity Capture-MS Homo sapiens
586 PNPLA2  
Affinity Capture-Western Homo sapiens
587 EFEMP1 2202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
588 COPS4 51138
Co-fractionation Homo sapiens
589 MARS 4141
Co-fractionation Homo sapiens
590 PPP2R1A 5518
Co-fractionation Homo sapiens
591 PDIA6 10130
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
592 SLX4  
Affinity Capture-MS Homo sapiens
593 GOLGA4  
Co-fractionation Homo sapiens
594 PRDX4 10549
Proximity Label-MS Homo sapiens
595 HIST1H1C 3006
Co-fractionation Homo sapiens
596 CALR 811
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
597 SIGLEC12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
598 TFCP2 7024
Affinity Capture-MS Homo sapiens
599 LCT  
Affinity Capture-Western Homo sapiens
600 MAPRE1 22919
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
601 UBQLN4 56893
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
602 LCN6  
Affinity Capture-MS Homo sapiens
603 YAF2  
Affinity Capture-MS Homo sapiens
604 DPH1  
Two-hybrid Homo sapiens
605 DPEP3 64180
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
606 HSPA8 3312
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
607 FAS 355
Affinity Capture-Western Homo sapiens
608 NCOA1  
Affinity Capture-MS Homo sapiens
609 PSME3 10197
Two-hybrid Homo sapiens
610 PAM16  
Co-fractionation Homo sapiens
611 HSPBP1 23640
Reconstituted Complex Homo sapiens
612 ATP5J 522
Co-fractionation Homo sapiens
613 RPL27 6155
Cross-Linking-MS (XL-MS) Homo sapiens
614 PRAP1  
Affinity Capture-MS Homo sapiens
615 BCAR1 9564
Two-hybrid Homo sapiens
616 S100A2 6273
Co-fractionation Homo sapiens
617 ATP5A1 498
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
618 P4HA1 5033
Proximity Label-MS Homo sapiens
619 PTPRN2  
Proximity Label-MS Homo sapiens
620 UBE2T  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
621 BPIFB6  
Affinity Capture-MS Homo sapiens
622 GAL  
Affinity Capture-MS Homo sapiens
623 ST6GALNAC6 30815
Affinity Capture-MS Homo sapiens
624 CUL4B 8450
Affinity Capture-MS Homo sapiens
625 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
626 IGF1R 3480
Affinity Capture-MS Homo sapiens
627 CCT6A 908
Co-fractionation Homo sapiens
628 CHCHD3 54927
Co-fractionation Homo sapiens
629 CLNS1A 1207
Co-fractionation Homo sapiens
630 MEX3C 51320
Affinity Capture-MS Homo sapiens
631 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
632 KLK1 3816
Affinity Capture-MS Homo sapiens
633 SRRT 51593
Co-fractionation Homo sapiens
634 CBX3 11335
Co-fractionation Homo sapiens
635 CD8A 925
Affinity Capture-MS Homo sapiens
636 PLOD2 5352
Proximity Label-MS Homo sapiens
637 ABCF2 10061
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
638 MST1 4485
Affinity Capture-MS Homo sapiens
639 GPC5 2262
Affinity Capture-MS Homo sapiens
640 SDF2L1 23753
Affinity Capture-MS Homo sapiens
641 GLIPR1  
Affinity Capture-MS Homo sapiens
642 NTRK1 4914
Affinity Capture-MS Homo sapiens
643 DHX9 1660
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
644 LDHAL6A  
Cross-Linking-MS (XL-MS) Homo sapiens
645 PCDHB3  
Affinity Capture-MS Homo sapiens
646 U2AF2 11338
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
647 PRPF8 10594
Co-fractionation Homo sapiens
648 NCL 4691
Co-fractionation Homo sapiens
649 B3GAT2  
Affinity Capture-MS Homo sapiens
650 DNAJA1 3301
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
651 IDS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
652 CDHR4  
Affinity Capture-MS Homo sapiens
653 DNAJB1 3337
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
654 RPN1 6184
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
655 SPACA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
656 COPS3 8533
Co-fractionation Homo sapiens
657 RLIM 51132
Affinity Capture-MS Homo sapiens
658 SUB1 10923
Co-fractionation Homo sapiens
659 INSL6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
660 TCTN1  
Affinity Capture-MS Homo sapiens
661 FUT7  
Affinity Capture-MS Homo sapiens
662 HNRNPA3 220988
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
663 HDAC5 10014
Affinity Capture-MS Homo sapiens
664 GFAP 2670
Affinity Capture-MS Homo sapiens
665 MYH9 4627
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
666 NUP210 23225
Proximity Label-MS Homo sapiens
667 RMDN3 55177
Co-fractionation Homo sapiens
668 RAN 5901
Co-fractionation Homo sapiens
669 SP1  
Co-fractionation Homo sapiens
670 HPSE2  
Affinity Capture-MS Homo sapiens
671 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
672 PA2G4 5036
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
673 HSPA1L 3305
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
674 OGT 8473
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
675 EFNA4  
Affinity Capture-MS Homo sapiens
676 GPC4 2239
Affinity Capture-MS Homo sapiens
677 NDST2  
Affinity Capture-MS Homo sapiens
678 CDC73  
Affinity Capture-MS Homo sapiens
679 DNAJB12 54788
Affinity Capture-MS Homo sapiens
680 MSH2 4436
Co-fractionation Homo sapiens
681 WNT3A 89780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
682 BAG2 9532
Affinity Capture-MS Homo sapiens
683 SMARCA5 8467
Co-fractionation Homo sapiens
684 RSF1  
Co-fractionation Homo sapiens
685 AHNAK 79026
Affinity Capture-MS Homo sapiens
686 HDAC2 3066
Co-fractionation Homo sapiens
687 B3GNT3 10331
Affinity Capture-MS Homo sapiens
688 METTL21A  
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
689 SIRPA 140885
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
690 DIRAS2 54769
Affinity Capture-MS Homo sapiens
691 PRSS50  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
692 NR3C1 2908
Affinity Capture-MS Homo sapiens
693 PSMA2 5683
Affinity Capture-MS Homo sapiens
694 DNAJC17  
Co-fractionation Homo sapiens
695 OSGEP 55644
Co-fractionation Homo sapiens
696 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
697 YY1 7528
Co-localization Homo sapiens
698 LAMA1 284217
Affinity Capture-MS Homo sapiens
699 FBXO6 26270
Affinity Capture-MS Homo sapiens
700 EIF4A1 1973
Co-fractionation Homo sapiens
701 METTL21B  
Affinity Capture-MS Homo sapiens
702 HNRNPUL1 11100
Co-fractionation Homo sapiens
703 RCN1 5954
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
704 LAMTOR5 10542
Co-fractionation Homo sapiens
705 OCIAD1 54940
Co-fractionation Homo sapiens
706 GYLTL1B 120071
Affinity Capture-MS Homo sapiens
707 SAP30 8819
Co-fractionation Homo sapiens
708 PRKCSH 5589
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
709 SERPINF1 5176
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
710 TMEM132A 54972
Reconstituted Complex Homo sapiens
711 FLNB 2317
Co-fractionation Homo sapiens
712 KLK3  
Affinity Capture-MS Homo sapiens
713 EMC2 9694
Proximity Label-MS Homo sapiens
714 GJB1 2705
Affinity Capture-Western Homo sapiens
715 TRGV3  
Affinity Capture-MS Homo sapiens
716 TP63  
Affinity Capture-MS Homo sapiens
717 NENF 29937
Proximity Label-MS Homo sapiens
718 ERP29 10961
Proximity Label-MS Homo sapiens
719 RPA4  
Proximity Label-MS Homo sapiens
720 ZBTB25  
Affinity Capture-MS Homo sapiens
721 PTPRN  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
722 DNAJC10 54431
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
723 CCDC124 115098
Cross-Linking-MS (XL-MS) Homo sapiens
724 RAF1 5894
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
725 HYOU1 10525
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
726 RANBP1 5902
Co-fractionation Homo sapiens
727 TXNDC5 81567
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
728 SEPT7 989
Affinity Capture-MS Homo sapiens
729 HAX1  
Affinity Capture-MS Homo sapiens
730 ISLR 3671
Affinity Capture-MS Homo sapiens
731 NPB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
732 Pias1  
Two-hybrid Mus musculus
733 HSPA9 3313
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
734 IGHV4-31 28396
Affinity Capture-MS Homo sapiens
735 AKAP1 8165
Proximity Label-MS Homo sapiens
736 FLOT1 10211
Cross-Linking-MS (XL-MS) Homo sapiens
737 CSH2  
Affinity Capture-MS Homo sapiens
738 RBBP8  
Affinity Capture-MS Homo sapiens
739 COL20A1  
Affinity Capture-MS Homo sapiens
740 AHSA1 10598
Affinity Capture-MS Homo sapiens
741 VWCE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
742 APOA1BP 128240
Affinity Capture-MS Homo sapiens
743 LAMB1 3912
Proximity Label-MS Homo sapiens
744 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
745 PHB2 11331
Co-fractionation Homo sapiens
746 NRROS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
747 LDHAL6B 92483