Gene description for TSHR
Gene name
thyroid stimulating hormone receptor
Gene symbol
TSHR
Other names/aliases
CHNG1 LGR3 hTSHR-I
Species
Homo sapiens
Database cross references - TSHR
ExoCarta
ExoCarta_7253
Vesiclepedia
VP_7253
Entrez Gene
7253
HGNC
12373
MIM
603372
UniProt
P16473
TSHR identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for TSHR
Experiment description of studies that identified TSHR in exosomes
1
Experiment ID
211
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
MISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
EV Enriched markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for TSHR
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
FN1
2335
Invivo
Homo sapiens
2
FLNB
2317
Invitro
Homo sapiens
Invivo
Homo sapiens
3
GNA13
10672
Affinity Capture-MS
Homo sapiens
4
CALR
811
Invivo
Homo sapiens
Invitro
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
STAT3
6774
Affinity Capture-MS
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
6
HSPA5
3309
Invivo
Homo sapiens
Invitro
Homo sapiens
7
TSHB
Invivo
Homo sapiens
8
GNA12
2768
Affinity Capture-MS
Homo sapiens
9
JAK2
3717
Invivo
Homo sapiens
10
JAK1
3716
Invivo
Homo sapiens
Invitro
Homo sapiens
11
CANX
821
Invivo
Homo sapiens
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which TSHR is involved