Gene description for OS9
Gene name osteosarcoma amplified 9, endoplasmic reticulum lectin
Gene symbol OS9
Other names/aliases ERLEC2
Species Homo sapiens
 Database cross references - OS9
ExoCarta ExoCarta_10956
Entrez Gene 10956
HGNC 16994
MIM 609677
UniProt Q13438  
 OS9 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for OS9
Molecular Function
    glycoprotein binding GO:0001948 IDA
    carbohydrate binding GO:0030246 IEA
    protein binding GO:0005515 IPI
    protease binding GO:0002020 IEA
Biological Process
    response to endoplasmic reticulum stress GO:0034976 IDA
    negative regulation of retrograde protein transport, ER to cytosol GO:1904153 IMP
    protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 IMP
    protein retention in ER lumen GO:0006621 IDA
    ER-associated ubiquitin-dependent protein catabolic process GO:0030433 IMP
    protein ubiquitination GO:0016567 IMP
    protein targeting GO:0006605 IEA
Subcellular Localization
    Hrd1p ubiquitin ligase complex GO:0000836 NAS
    endoplasmic reticulum quality control compartment GO:0044322 TAS
    endoplasmic reticulum lumen GO:0005788 IDA
 Experiment description of studies that identified OS9 in exosomes
Experiment ID 66
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for OS9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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