Experiment description of studies that identified LIFR in exosomes

1 Experiment ID 235 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Cytosolic markers ✘ EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for LIFR

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PTPN11 5781 Invitro Homo sapiens Invivo Homo sapiens 2 IL6ST 3572 Affinity Capture-Western Homo sapiens 3 CNTFR 1271 Invitro Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 4 LIF 3976 Reconstituted Complex Homo sapiens 5 OSM 5008 Invivo Homo sapiens Affinity Capture-Western Homo sapiens 6 PLCG1 5335 Invivo Homo sapiens 7 CTF1   Invivo Homo sapiens 8 POU2F1   Invitro Homo sapiens 9 PTPN6 5777 Invivo Homo sapiens View the network

Pathways in which LIFR is involved

No pathways found