Gene description for FAM19A2
Gene name family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
Gene symbol FAM19A2
Other names/aliases TAFA-2
TAFA2
Species Homo sapiens
 Database cross references - FAM19A2
ExoCarta ExoCarta_338811
Vesiclepedia VP_338811
Entrez Gene 338811
HGNC 21589
UniProt Q8N3H0  
 FAM19A2 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for FAM19A2
Molecular Function
    receptor ligand activity GO:0048018 IBA
Biological Process
    signal transduction GO:0007165 IEA
    memory GO:0007613 ISS
    visual learning GO:0008542 ISS
Subcellular Localization
    extracellular space GO:0005615 IBA
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified FAM19A2 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for FAM19A2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KIR3DL1  
Reconstituted Complex Homo sapiens
2 PTPRU  
Affinity Capture-MS Homo sapiens
3 HSPA5 3309
Affinity Capture-MS Homo sapiens
4 ERN1  
Affinity Capture-MS Homo sapiens
5 TXNDC16 57544
Affinity Capture-MS Homo sapiens
6 SUSD1 64420
Affinity Capture-MS Homo sapiens
7 RNF167 26001
Reconstituted Complex Homo sapiens
8 ST3GAL6 10402
Affinity Capture-MS Homo sapiens
9 SORL1 6653
Affinity Capture-MS Homo sapiens
10 MICA 100507436
Affinity Capture-MS Homo sapiens
11 KIR3DL3  
Reconstituted Complex Homo sapiens
12 KIR3DL2  
Reconstituted Complex Homo sapiens
13 BTD 686
Affinity Capture-MS Homo sapiens
14 CNTNAP1 8506
Affinity Capture-MS Homo sapiens
15 M6PR 4074
Affinity Capture-MS Homo sapiens
16 TENM3 55714
Affinity Capture-MS Homo sapiens
17 EMC4 51234
Affinity Capture-MS Homo sapiens
18 FREM2 341640
Affinity Capture-MS Homo sapiens
19 INSR 3643
Affinity Capture-MS Homo sapiens
20 TMEM67 91147
Affinity Capture-MS Homo sapiens
21 LARGE 9215
Affinity Capture-MS Homo sapiens
22 POMGNT2  
Affinity Capture-MS Homo sapiens
23 COL6A2 1292
Affinity Capture-MS Homo sapiens
24 LEPR 3953
Affinity Capture-MS Homo sapiens
25 VWDE  
Affinity Capture-MS Homo sapiens
26 CD109 135228
Affinity Capture-MS Homo sapiens
27 MRC2 9902
Affinity Capture-MS Homo sapiens
28 ATRNL1 26033
Affinity Capture-MS Homo sapiens
29 LRP6 4040
Affinity Capture-MS Homo sapiens
30 KIR2DL5A  
Reconstituted Complex Homo sapiens
31 PAM 5066
Affinity Capture-MS Homo sapiens
32 IGF2R 3482
Affinity Capture-MS Homo sapiens
33 TCTN2  
Affinity Capture-MS Homo sapiens
34 LDLR 3949
Affinity Capture-MS Homo sapiens
35 CRELD2 79174
Affinity Capture-MS Homo sapiens
36 TGFBR3 7049
Affinity Capture-MS Homo sapiens
37 MARS2 92935
Affinity Capture-MS Homo sapiens
38 EMC3 55831
Affinity Capture-MS Homo sapiens
39 LIFR 3977
Affinity Capture-MS Homo sapiens
40 LAMA3 3909
Affinity Capture-MS Homo sapiens
41 NLGN2 57555
Affinity Capture-MS Homo sapiens
42 ITGA4 3676
Affinity Capture-MS Homo sapiens
43 CPE 1363
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM19A2 is involved
No pathways found





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