Experiment description of studies that identified LEPR in exosomes

1 Experiment ID 235 MISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Enriched markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for LEPR

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PIN1 5300 Two-hybrid Homo sapiens 2 SNX1 6642 Invivo Homo sapiens 3 LEP   Invivo Homo sapiens 4 SNX2 6643 Invivo Homo sapiens Invitro Homo sapiens 5 STAT3 6774 Invivo Homo sapiens 6 SOCS3 9021 Reconstituted Complex Homo sapiens 7 DGKZ   Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens 8 JAK3 3718 Affinity Capture-Western Homo sapiens 9 JAK2 3717 Invitro Homo sapiens 10 SNX4 8723 Invivo Homo sapiens 11 SNX6 58533 Invivo Homo sapiens Invitro Homo sapiens View the network

Pathways in which LEPR is involved

No pathways found