Gene description for PIN1
Gene name	peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Gene symbol	PIN1
Other names/aliases	DOD UBL5
Species	Homo sapiens
Database cross references - PIN1
ExoCarta	ExoCarta_5300
Entrez Gene	5300
HGNC	8988
MIM	601052
UniProt	Q13526
PIN1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for PIN1

Molecular Function     phosphoserine binding GO:0050815 IDA     phosphothreonine binding GO:0050816 IPI     peptidyl-prolyl cis-trans isomerase activity GO:0003755 IDA     mitogen-activated protein kinase kinase binding GO:0031434 IPI     protein binding GO:0005515 IPI     GTPase activating protein binding GO:0032794 IPI Biological Process     regulation of mitotic nuclear division GO:0007088 TAS     negative regulation of type I interferon production GO:0032480 TAS     negative regulation of cell motility GO:2000146 IDA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IDA     positive regulation of ubiquitin-protein transferase activity GO:0051443 IDA     cell cycle GO:0007049 IEA     regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 IDA     cytokine-mediated signaling pathway GO:0019221 TAS     innate immune response GO:0045087 TAS     negative regulation of ERK1 and ERK2 cascade GO:0070373 IDA     positive regulation of protein phosphorylation GO:0001934 IGI     regulation of cytokinesis GO:0032465 IMP     positive regulation of GTPase activity GO:0043547 IMP     protein peptidyl-prolyl isomerization GO:0000413 IEA Subcellular Localization     nuclear speck GO:0016607 IEA     cytoplasm GO:0005737 IEA     nucleoplasm GO:0005654 TAS     midbody GO:0030496 IDA     nucleus GO:0005634 IDA