Gene description for TAB3
Gene name	TGF-beta activated kinase 1/MAP3K7 binding protein 3
Gene symbol	TAB3
Other names/aliases	MAP3K7IP3 NAP1
Species	Homo sapiens
Database cross references - TAB3
ExoCarta	ExoCarta_257397
Entrez Gene	257397
HGNC	30681
MIM	300480
UniProt	Q8N5C8
TAB3 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for TAB3

Molecular Function     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IEA Biological Process     toll-like receptor 2 signaling pathway GO:0034134 TAS     JNK cascade GO:0007254 TAS     toll-like receptor 10 signaling pathway GO:0034166 TAS     I-kappaB kinase/NF-kappaB signaling GO:0007249 TAS     toll-like receptor 5 signaling pathway GO:0034146 TAS     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     toll-like receptor 3 signaling pathway GO:0034138 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     nucleotide-binding oligomerization domain containing signaling pathway GO:0070423 TAS     activation of MAPK activity GO:0000187 TAS     nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0035872 TAS     stress-activated MAPK cascade GO:0051403 TAS     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     innate immune response GO:0045087 TAS     toll-like receptor signaling pathway GO:0002224 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 TAS     toll-like receptor 9 signaling pathway GO:0034162 TAS Subcellular Localization     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IDA     extracellular exosome GO:0070062 IDA     plasma membrane GO:0005886 TAS     endosome membrane GO:0010008 TAS     cytosol GO:0005829 TAS