Gene description for IKBKG
Gene name	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Gene symbol	IKBKG
Other names/aliases	AMCBX1 FIP-3 FIP3 Fip3p IKK-gamma IMD33 IP IP1 IP2 IPD2 NEMO ZC2HC9
Species	Homo sapiens
Database cross references - IKBKG
ExoCarta	ExoCarta_8517
Entrez Gene	8517
HGNC	5961
MIM	300248
UniProt	Q9Y6K9
IKBKG identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for IKBKG

Molecular Function     peroxisome proliferator activated receptor binding GO:0042975 IEA     protein heterodimerization activity GO:0046982 IDA     linear polyubiquitin binding GO:1990450 IDA     protein homodimerization activity GO:0042803 IDA     protein binding GO:0005515 IPI     K63-linked polyubiquitin binding GO:0070530 IEA     signal transducer activity GO:0004871 TAS     ubiquitin protein ligase binding GO:0031625 IPI     protein domain specific binding GO:0019904 IPI     metal ion binding GO:0046872 IEA Biological Process     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 TAS     I-kappaB kinase/NF-kappaB signaling GO:0007249 TAS     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     activation of MAPK activity GO:0000187 TAS     toll-like receptor 3 signaling pathway GO:0034138 TAS     toll-like receptor 5 signaling pathway GO:0034146 TAS     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     cellular response to DNA damage stimulus GO:0006974 IDA     toll-like receptor 9 signaling pathway GO:0034162 TAS     transcription, DNA-templated GO:0006351 IEA     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     toll-like receptor 10 signaling pathway GO:0034166 TAS     toll-like receptor signaling pathway GO:0002224 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     toll-like receptor 2 signaling pathway GO:0034134 TAS     positive regulation of type I interferon production GO:0032481 TAS     immune response GO:0006955 TAS     negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway GO:1902236 IEA     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     activation of NF-kappaB-inducing kinase activity GO:0007250 IEA     JNK cascade GO:0007254 TAS     nucleotide-binding oligomerization domain containing signaling pathway GO:0070423 TAS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     positive regulation of NF-kappaB transcription factor activity GO:0051092 TAS     apoptotic process GO:0006915 TAS     T cell receptor signaling pathway GO:0050852 TAS     stress-activated MAPK cascade GO:0051403 TAS     response to virus GO:0009615 TAS     establishment of vesicle localization GO:0051650 IMP     innate immune response GO:0045087 TAS     B cell homeostasis GO:0001782 IEA     inflammatory response GO:0006954 TAS     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     viral process GO:0016032 IEA     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     negative regulation of neuron death GO:1901215 TAS     nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0035872 TAS Subcellular Localization     mitotic spindle GO:0072686 IDA     ubiquitin ligase complex GO:0000151 IPI     spindle pole GO:0000922 IDA     IkappaB kinase complex GO:0008385 TAS     intracellular GO:0005622 IDA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     nucleus GO:0005634 IDA