Gene description for ACBD6
Gene name acyl-CoA binding domain containing 6
Gene symbol ACBD6
Other names/aliases -
Species Homo sapiens
 Database cross references - ACBD6
ExoCarta ExoCarta_84320
Vesiclepedia VP_84320
Entrez Gene 84320
HGNC 23339
MIM 616352
UniProt Q9BR61  
 ACBD6 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ACBD6
Molecular Function
    fatty-acyl-CoA binding GO:0000062 IBA
    fatty-acyl-CoA binding GO:0000062 IMP
    protein binding GO:0005515 IPI
    lipid binding GO:0008289 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ACBD6 in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ACBD6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 URM1  
Affinity Capture-MS Homo sapiens
3 NMT2 9397
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
4 AP5S1  
Affinity Capture-MS Homo sapiens
5 IKBKG 8517
Reconstituted Complex Homo sapiens
6 TULP3 7289
Affinity Capture-MS Homo sapiens
7 HIF1AN 55662
Affinity Capture-MS Homo sapiens
8 FAM110D  
Affinity Capture-MS Homo sapiens
9 NMT1 4836
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
10 C11orf31  
Affinity Capture-MS Homo sapiens
11 HSPB1 3315
Two-hybrid Homo sapiens
12 ATG7 10533
Affinity Capture-MS Homo sapiens
13 CTU2 348180
Affinity Capture-MS Homo sapiens
14 CTU1 90353
Affinity Capture-MS Homo sapiens
15 FAS 355
Proximity Label-MS Homo sapiens
16 RPS7 6201
Cross-Linking-MS (XL-MS) Homo sapiens
17 HOXC8  
Affinity Capture-MS Homo sapiens
18 HES6  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ACBD6 is involved
PathwayEvidenceSource
Fatty acid metabolism TAS Reactome
Metabolism TAS Reactome
Metabolism of lipids TAS Reactome
Mitochondrial Fatty Acid Beta-Oxidation TAS Reactome





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