Gene description for FAS
Gene name Fas cell surface death receptor
Gene symbol FAS
Other names/aliases ALPS1A
APO-1
APT1
CD95
FAS1
FASTM
TNFRSF6
Species Homo sapiens
 Database cross references - FAS
ExoCarta ExoCarta_355
Vesiclepedia VP_355
Entrez Gene 355
HGNC 11920
MIM 134637
UniProt P25445  
 FAS identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Thymus 23844026    
 Gene ontology annotations for FAS
Molecular Function
    tumor necrosis factor receptor activity GO:0005031 IBA
    tumor necrosis factor receptor activity GO:0005031 IDA
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 IDA
    kinase binding GO:0019900 IPI
    signaling receptor activity GO:0038023 NAS
    identical protein binding GO:0042802 IPI
Biological Process
    positive regulation of protein phosphorylation GO:0001934 IMP
    apoptotic process GO:0006915 IDA
    activation-induced cell death of T cells GO:0006924 IBA
    immune response GO:0006955 IEA
    signal transduction GO:0007165 TAS
    extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 IDA
    regulation of stress-activated MAPK cascade GO:0032872 IBA
    regulation of stress-activated MAPK cascade GO:0032872 IMP
    tumor necrosis factor-mediated signaling pathway GO:0033209 IEA
    cellular response to amino acid starvation GO:0034198 IMP
    Fas signaling pathway GO:0036337 IDA
    Fas signaling pathway GO:0036337 IMP
    regulation of apoptotic process GO:0042981 NAS
    positive regulation of apoptotic process GO:0043065 IDA
    positive regulation of apoptotic process GO:0043065 IMP
    negative regulation of apoptotic process GO:0043066 IBA
    protein-containing complex assembly GO:0065003 TAS
    cellular response to mechanical stimulus GO:0071260 IEP
    cellular response to hyperoxia GO:0071455 IMP
    motor neuron apoptotic process GO:0097049 IBA
    extrinsic apoptotic signaling pathway GO:0097191 IMP
    necroptotic signaling pathway GO:0097527 IBA
    necroptotic signaling pathway GO:0097527 IMP
    positive regulation of reactive oxygen species biosynthetic process GO:1903428 IDA
    positive regulation of cysteine-type endopeptidase activity GO:2001056 IMP
    positive regulation of apoptotic signaling pathway GO:2001235 IMP
Subcellular Localization
    cytosol GO:0005829 IDA
    cytosol GO:0005829 NAS
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 IMP
    plasma membrane GO:0005886 TAS
    external side of plasma membrane GO:0009897 IBA
    cell surface GO:0009986 IDA
    nuclear body GO:0016604 IDA
    death-inducing signaling complex GO:0031264 IDA
    CD95 death-inducing signaling complex GO:0031265 IBA
    CD95 death-inducing signaling complex GO:0031265 IDA
    membrane raft GO:0045121 IBA
    membrane raft GO:0045121 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified FAS in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FAS
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KPNA6 23633
Proximity Label-MS Homo sapiens
2 VKORC1L1 154807
Proximity Label-MS Homo sapiens
3 HNRNPC 3183
Two-hybrid Homo sapiens
4 CASP8 841
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
5 KPNA3 3839
Proximity Label-MS Homo sapiens
6 CUEDC2  
Proximity Label-MS Homo sapiens
7 NDNL2 56160
Proximity Label-MS Homo sapiens
8 C1orf27 54953
Affinity Capture-MS Homo sapiens
9 MPP5 64398
Proximity Label-MS Homo sapiens
10 CFAP36 112942
Proximity Label-MS Homo sapiens
11 ATG5 9474
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
12 STT3B 201595
Proximity Label-MS Homo sapiens
13 PRAM1  
Affinity Capture-Western Homo sapiens
14 EIF3K 27335
Proximity Label-MS Homo sapiens
15 IPO7 10527
Proximity Label-MS Homo sapiens
16 CREB3L2 64764
Proximity Label-MS Homo sapiens
17 ESYT1 23344
Proximity Label-MS Homo sapiens
18 SQSTM1 8878
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
19 GADD45A  
Two-hybrid Homo sapiens
20 CSNK1A1 1452
Proximity Label-MS Homo sapiens
21 USP5 8078
Proximity Label-MS Homo sapiens
22 NUP62 23636
Proximity Label-MS Homo sapiens
23 STYK1  
Affinity Capture-MS Homo sapiens
24 CLNS1A 1207
Proximity Label-MS Homo sapiens
25 PTTG1  
Proximity Label-MS Homo sapiens
26 RPL10 6134
Proximity Label-MS Homo sapiens
27 TRADD 8717
Affinity Capture-Western Homo sapiens
28 CBWD2  
Proximity Label-MS Homo sapiens
29 UBC 7316
Proximity Label-MS Homo sapiens
30 SAMD1  
Proximity Label-MS Homo sapiens
31 KPNA2 3838
Proximity Label-MS Homo sapiens
32 TERF2IP 54386
Proximity Label-MS Homo sapiens
33 LRRC59 55379
Proximity Label-MS Homo sapiens
34 CFL1 1072
Proximity Label-MS Homo sapiens
35 RIPK1 8737
Two-hybrid Homo sapiens
36 KPNB1 3837
Proximity Label-MS Homo sapiens
37 C17orf75 64149
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 TPT1 7178
Proximity Label-MS Homo sapiens
39 PEX1 5189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ARHGDIA 396
Co-purification Homo sapiens
41 CTU2 348180
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 ATG13 9776
Proximity Label-MS Homo sapiens
43 RNH1 6050
Proximity Label-MS Homo sapiens
44 MAP3K5 4217
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
45 PNMA1 9240
Proximity Label-MS Homo sapiens
46 COPB2 9276
Proximity Label-MS Homo sapiens
47 ZPR1 8882
Proximity Label-MS Homo sapiens
48 LPCAT2 54947
Proximity Label-MS Homo sapiens
49 DPM1 8813
Proximity Label-MS Homo sapiens
50 WDR11 55717
Affinity Capture-MS Homo sapiens
51 OTUB1 55611
Proximity Label-MS Homo sapiens
52 RINT1 60561
Proximity Label-MS Homo sapiens
53 MDN1 23195
Affinity Capture-MS Homo sapiens
54 CCS 9973
Proximity Label-MS Homo sapiens
55 TSNAX 7257
Proximity Label-MS Homo sapiens
56 COMMD9 29099
Proximity Label-MS Homo sapiens
57 SPATA5 166378
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 YES1 7525
Affinity Capture-Western Homo sapiens
59 TFIP11  
Proximity Label-MS Homo sapiens
60 SRC 6714
Affinity Capture-Western Homo sapiens
61 GCAT  
Affinity Capture-MS Homo sapiens
62 DNAJC16  
Proximity Label-MS Homo sapiens
63 NUP93 9688
Proximity Label-MS Homo sapiens
64 ESYT2 57488
Proximity Label-MS Homo sapiens
65 UGT1A10  
Affinity Capture-MS Homo sapiens
66 PDCD2 5134
Proximity Label-MS Homo sapiens
67 RHOA 387
Co-purification Homo sapiens
Co-localization Homo sapiens
68 NOL3 8996
Phenotypic Suppression Homo sapiens
69 COPG1 22820
Proximity Label-MS Homo sapiens
70 UGDH 7358
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 GRWD1 83743
Proximity Label-MS Homo sapiens
72 OTUD6B 51633
Proximity Label-MS Homo sapiens
73 FAF1 11124
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
74 CRMP1 1400
Two-hybrid Homo sapiens
75 HBS1L 10767
Proximity Label-MS Homo sapiens
76 NDUFAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 UFSP2 55325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 ADD1 118
Proximity Label-MS Homo sapiens
79 EXOSC6 118460
Proximity Label-MS Homo sapiens
80 SPATA5L1 79029
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 PPP1R15B  
Proximity Label-MS Homo sapiens
82 SNX27 81609
Affinity Capture-MS Homo sapiens
83 PRKCD 5580
Proximity Label-MS Homo sapiens
84 MAPRE1 22919
Proximity Label-MS Homo sapiens
85 CYB5B 80777
Proximity Label-MS Homo sapiens
86 ASF1A 25842
Proximity Label-MS Homo sapiens
87 RNF123 63891
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
88 KPNA1 3836
Proximity Label-MS Homo sapiens
89 CFLAR  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
90 UBAC1 10422
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
PCA Homo sapiens
91 DPH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 EEF1A1 1915
Two-hybrid Homo sapiens
93 EHD1 10938
Affinity Capture-MS Homo sapiens
94 ERCC6L 54821
Proximity Label-MS Homo sapiens
95 BAG6 7917
Two-hybrid Homo sapiens
96 LSM12 124801
Proximity Label-MS Homo sapiens
97 FAS 355
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Proximity Label-MS Homo sapiens
98 TNF  
Affinity Capture-Western Homo sapiens
99 METTL13 51603
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 RB1 5925
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 TMEM25  
Affinity Capture-MS Homo sapiens
102 EFNA2  
Affinity Capture-MS Homo sapiens
103 EIF2AK2 5610
Proximity Label-MS Homo sapiens
104 EIF3I 8668
Proximity Label-MS Homo sapiens
105 DPEP2  
Affinity Capture-MS Homo sapiens
106 R3HCC1L  
Proximity Label-MS Homo sapiens
107 FASLG 356
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
108 IFT27 11020
Affinity Capture-MS Homo sapiens
109 UBQLN1 29979
Two-hybrid Homo sapiens
110 ALDH16A1 126133
Affinity Capture-MS Homo sapiens
111 GPD1 2819
Affinity Capture-MS Homo sapiens
112 CERS2 29956
Proximity Label-MS Homo sapiens
113 ARL2BP 23568
Proximity Label-MS Homo sapiens
114 TMX1 81542
Two-hybrid Homo sapiens
115 RUFY1 80230
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 CDC34 997
Proximity Label-MS Homo sapiens
117 IMPACT 55364
Proximity Label-MS Homo sapiens
118 SDCCAG3  
Proximity Label-MS Homo sapiens
119 MTFR1L 56181
Proximity Label-MS Homo sapiens
120 AGK 55750
Affinity Capture-MS Homo sapiens
121 BRE 9577
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
122 NDUFA8 4702
Proximity Label-MS Homo sapiens
123 SNX1 6642
Proximity Label-MS Homo sapiens
124 PRKAG1 5571
Affinity Capture-MS Homo sapiens
125 DTNBP1  
Proximity Label-MS Homo sapiens
126 LRIF1  
Two-hybrid Homo sapiens
127 APOA5 116519
Two-hybrid Homo sapiens
128 ASNA1 439
Proximity Label-MS Homo sapiens
129 TNFSF13 8741
Reconstituted Complex Homo sapiens
130 UBE2I 7329
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
131 TUBB2B 347733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 ATP6V1C1 528
Proximity Label-MS Homo sapiens
133 FAM118B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 UBXN1 51035
Proximity Label-MS Homo sapiens
135 FYN 2534
Affinity Capture-Western Homo sapiens
136 ABHD11 83451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 HAUS8  
Proximity Label-MS Homo sapiens
138 VCP 7415
Affinity Capture-MS Homo sapiens
139 SARAF  
Proximity Label-MS Homo sapiens
140 C1orf198 84886
Proximity Label-MS Homo sapiens
141 FAIM  
Proximity Label-MS Homo sapiens
142 GPR182  
Affinity Capture-MS Homo sapiens
143 SRPR 6734
Proximity Label-MS Homo sapiens
144 RAP1A 5906
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
145 ALDH3B1 221
Affinity Capture-MS Homo sapiens
146 MKRN2 23609
Proximity Label-MS Homo sapiens
147 NCS1 23413
Proximity Label-MS Homo sapiens
148 IDI1 3422
Proximity Label-MS Homo sapiens
149 TNFRSF10C  
Affinity Capture-MS Homo sapiens
150 ANKHD1 54882
Proximity Label-MS Homo sapiens
151 PML 5371
Affinity Capture-Western Homo sapiens
152 PIK3R1 5295
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
153 COMMD3 23412
Proximity Label-MS Homo sapiens
154 PBXIP1 57326
Proximity Label-MS Homo sapiens
155 EIF3H 8667
Proximity Label-MS Homo sapiens
156 Ube2i  
Two-hybrid Mus musculus
157 MAGEB2 4113
Proximity Label-MS Homo sapiens
158 MAPK8 5599
Co-purification Homo sapiens
Co-localization Homo sapiens
159 SND1 27044
Proximity Label-MS Homo sapiens
160 ARL4C 10123
Affinity Capture-MS Homo sapiens
161 PPM1G 5496
Proximity Label-MS Homo sapiens
162 IFT57 55081
Proximity Label-MS Homo sapiens
163 SFXN5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 DAXX  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
165 UBXN6 80700
Proximity Label-MS Homo sapiens
166 PEX19 5824
Proximity Label-MS Homo sapiens
167 TCAP  
Two-hybrid Homo sapiens
168 DNAJC7 7266
Proximity Label-MS Homo sapiens
169 TRAFD1  
Proximity Label-MS Homo sapiens
170 TMF1 7110
Proximity Label-MS Homo sapiens
171 CHP1 11261
Proximity Label-MS Homo sapiens
172 SEC63 11231
Proximity Label-MS Homo sapiens
173 ANKZF1 55139
Proximity Label-MS Homo sapiens
174 PICK1  
Affinity Capture-MS Homo sapiens
175 HSPA5 3309
Affinity Capture-Western Homo sapiens
176 POLR2C 5432
Proximity Label-MS Homo sapiens
177 TUBB 203068
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 MTMR14 64419
Proximity Label-MS Homo sapiens
179 DESI1  
Proximity Label-MS Homo sapiens
180 STRN3 29966
Proximity Label-MS Homo sapiens
181 LRRC57 255252
Proximity Label-MS Homo sapiens
182 PRKCA 5578
Co-localization Homo sapiens
183 C14orf1 11161
Two-hybrid Homo sapiens
184 NDUFB10 4716
Proximity Label-MS Homo sapiens
185 ECD  
Proximity Label-MS Homo sapiens
186 MBD4  
Two-hybrid Homo sapiens
187 NUBP2 10101
Affinity Capture-MS Homo sapiens
188 BAG2 9532
Proximity Label-MS Homo sapiens
189 CTNNB1 1499
Co-localization Homo sapiens
190 POLR2E 5434
Proximity Label-MS Homo sapiens
191 CALCOCO1 57658
Proximity Label-MS Homo sapiens
192 TTC12  
Proximity Label-MS Homo sapiens
193 NPM3 10360
Proximity Label-MS Homo sapiens
194 TNFRSF1A 7132
Co-purification Homo sapiens
195 KCTD5 54442
Proximity Label-MS Homo sapiens
196 CUL3 8452
Affinity Capture-MS Homo sapiens
197 HSPA14 51182
Proximity Label-MS Homo sapiens
198 TUBB4B 10383
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 EPHX1 2052
Proximity Label-MS Homo sapiens
200 YY1 7528
Proximity Label-MS Homo sapiens
201 EIF4A1 1973
Proximity Label-MS Homo sapiens
202 IPO5 3843
Proximity Label-MS Homo sapiens
203 RAB35 11021
Proximity Label-MS Homo sapiens
204 TRAF3 7187
Reconstituted Complex Homo sapiens
205 RBBP4 5928
Proximity Label-MS Homo sapiens
206 GTF2E1 2960
Proximity Label-MS Homo sapiens
207 ADAM7  
Affinity Capture-MS Homo sapiens
208 ERP44 23071
Proximity Label-MS Homo sapiens
209 GINS3  
Proximity Label-MS Homo sapiens
210 IFFO2 126917
Proximity Label-MS Homo sapiens
211 CYP20A1 57404
Proximity Label-MS Homo sapiens
212 TYW1  
Proximity Label-MS Homo sapiens
213 CDYL 9425
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 SOAT1 6646
Proximity Label-MS Homo sapiens
215 ACSL3 2181
Proximity Label-MS Homo sapiens
216 KIF1BP 26128
Proximity Label-MS Homo sapiens
217 ACBD6 84320
Proximity Label-MS Homo sapiens
218 RPA3 6119
Proximity Label-MS Homo sapiens
219 FAM91A1 157769
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
220 NAP1L1 4673
Proximity Label-MS Homo sapiens
221 TRIM26 7726
Proximity Label-MS Homo sapiens
222 ALDH3B2  
Affinity Capture-MS Homo sapiens
223 TP63  
Affinity Capture-MS Homo sapiens
224 CASP10  
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
225 PTGES3 10728
Proximity Label-MS Homo sapiens
226 FAM21C 253725
Proximity Label-MS Homo sapiens
227 FAF2 23197
Two-hybrid Homo sapiens
228 ACAD9 28976
Affinity Capture-MS Homo sapiens
229 FAIM2  
Affinity Capture-Western Homo sapiens
230 DDRGK1 65992
Proximity Label-MS Homo sapiens
231 QTRT1 81890
Affinity Capture-MS Homo sapiens
232 AIP 9049
Proximity Label-MS Homo sapiens
233 ATP6V0B 533
Two-hybrid Homo sapiens
234 FBF1  
Two-hybrid Homo sapiens
235 MSN 4478
Co-purification Homo sapiens
236 MPI 4351
Affinity Capture-MS Homo sapiens
237 CETN2 1069
Proximity Label-MS Homo sapiens
238 STX17 55014
Proximity Label-MS Homo sapiens
239 UBXN2B  
Proximity Label-MS Homo sapiens
240 PDXDC1 23042
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 SKP1 6500
Proximity Label-MS Homo sapiens
242 SUMO1 7341
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
243 PELO 53918
Proximity Label-MS Homo sapiens
244 TUBB2A 7280
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 LBR 3930
Proximity Label-MS Homo sapiens
246 RELA 5970
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
247 POP7  
Proximity Label-MS Homo sapiens
248 Traf1  
Affinity Capture-Western Mus musculus
249 UBXN8  
Proximity Label-MS Homo sapiens
250 FADD 8772
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-localization Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
251 XBP1  
Proximity Label-MS Homo sapiens
252 RARA 5914
Affinity Capture-Western Homo sapiens
253 MYL6 4637
Proximity Label-MS Homo sapiens
254 C1orf43 25912
Proximity Label-MS Homo sapiens
255 NSMCE1  
Proximity Label-MS Homo sapiens
256 HAUS1  
Proximity Label-MS Homo sapiens
257 RHOBTB3 22836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
258 TP53 7157
Proximity Label-MS Homo sapiens
259 PGRMC1 10857
Proximity Label-MS Homo sapiens
260 MAP1S 55201
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 SSU72 29101
Proximity Label-MS Homo sapiens
262 ASF1B  
Proximity Label-MS Homo sapiens
263 MAEA 10296
Proximity Label-MS Homo sapiens
264 PWP1 11137
Proximity Label-MS Homo sapiens
265 GPN3  
Affinity Capture-MS Homo sapiens
266 EZR 7430
Co-purification Homo sapiens
267 ARF5 381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 COX16  
Affinity Capture-MS Homo sapiens
269 HIPK3 10114
Affinity Capture-Western Homo sapiens
270 PDCD6 10016
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
271 LCK 3932
Reconstituted Complex Homo sapiens
272 POMP  
Proximity Label-MS Homo sapiens
273 TUBB3 10381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 BID  
Co-localization Homo sapiens
Co-purification Homo sapiens
275 INTS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
276 BNIP2  
Proximity Label-MS Homo sapiens
277 GPD1L 23171
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 CHD1L 9557
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
279 CAV1 857
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
280 CREBZF  
Proximity Label-MS Homo sapiens
281 CCDC97  
Proximity Label-MS Homo sapiens
282 DHRS13  
Proximity Label-MS Homo sapiens
283 TUBB4A 10382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 TUBB6 84617
Affinity Capture-MS Homo sapiens
285 PCNA 5111
Proximity Label-MS Homo sapiens
286 ARPC4-TTLL3 100526693
Proximity Label-MS Homo sapiens
287 UFL1 23376
Proximity Label-MS Homo sapiens
288 LPCAT1 79888
Proximity Label-MS Homo sapiens
289 E2F3  
Proximity Label-MS Homo sapiens
290 RNASEH2A 10535
Proximity Label-MS Homo sapiens
291 TNFRSF10B 8795
Co-purification Homo sapiens
292 DNAJB11 51726
Proximity Label-MS Homo sapiens
293 CENPK  
Proximity Label-MS Homo sapiens
294 DHFR 1719
Proximity Label-MS Homo sapiens
295 RETSAT 54884
Proximity Label-MS Homo sapiens
296 SEC61B 10952
Proximity Label-MS Homo sapiens
297 PSMA5 5686
Proximity Label-MS Homo sapiens
298 CAPZA1 829
Proximity Label-MS Homo sapiens
299 PJA1  
Proximity Label-MS Homo sapiens
300 ATG4B 23192
Proximity Label-MS Homo sapiens
301 C19orf52  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
302 SMARCB1 6598
Proximity Label-MS Homo sapiens
303 TMEM109 79073
Proximity Label-MS Homo sapiens
304 ANXA5 308
Proximity Label-MS Homo sapiens
305 FGFR1OP  
Proximity Label-MS Homo sapiens
306 BICD2 23299
Proximity Label-MS Homo sapiens
307 COMMD7 149951
Proximity Label-MS Homo sapiens
308 TRMT112 51504
Proximity Label-MS Homo sapiens
309 CDR2  
Proximity Label-MS Homo sapiens
310 C1QBP 708
Proximity Label-MS Homo sapiens
311 MYL12A 10627
Proximity Label-MS Homo sapiens
312 EIF5A 1984
Proximity Label-MS Homo sapiens
313 PEX5 5830
Proximity Label-MS Homo sapiens
314 STC2 8614
Proximity Label-MS Homo sapiens
315 LTV1  
Proximity Label-MS Homo sapiens
316 C9orf72  
Affinity Capture-MS Homo sapiens
317 MOCS3 27304
Affinity Capture-MS Homo sapiens
318 CASP8AP2  
Affinity Capture-Western Homo sapiens
319 PTGES3L-AARSD1 100885850
Proximity Label-MS Homo sapiens
320 SSRP1 6749
Proximity Label-MS Homo sapiens
321 EIF2AK3  
Affinity Capture-Western Homo sapiens
322 ALDH1L2 160428
Affinity Capture-MS Homo sapiens
323 CAB39L 81617
Affinity Capture-MS Homo sapiens
324 CACYBP 27101
Proximity Label-MS Homo sapiens
325 C1orf74  
Affinity Capture-MS Homo sapiens
326 VEZT 55591
Proximity Label-MS Homo sapiens
327 CPSF3 51692
Proximity Label-MS Homo sapiens
328 WRB 7485
Affinity Capture-MS Homo sapiens
329 CYB5A 1528
Proximity Label-MS Homo sapiens
330 EP300 2033
Affinity Capture-MS Homo sapiens
331 ECSIT 51295
Affinity Capture-MS Homo sapiens
332 CCND3  
Two-hybrid Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here