Gene description for STX17
Gene name syntaxin 17
Gene symbol STX17
Other names/aliases -
Species Homo sapiens
 Database cross references - STX17
ExoCarta ExoCarta_55014
Vesiclepedia VP_55014
Entrez Gene 55014
HGNC 11432
MIM 604204
UniProt P56962  
 STX17 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for STX17
Molecular Function
    protein kinase binding GO:0019901 IEA
    SNAP receptor activity GO:0005484 IMP
    protein binding GO:0005515 IPI
    protein phosphatase binding GO:0019903 IPI
    SNARE binding GO:0000149 IDA
Biological Process
    autophagosome fusion GO:0000046 IMP
    Golgi organization GO:0007030 IMP
    protein localization to pre-autophagosomal structure GO:0034497 IDA
    ER to Golgi vesicle-mediated transport GO:0006888 IMP
    vesicle docking GO:0048278 IBA
    intracellular protein transport GO:0006886 IBA
    endoplasmic reticulum-Golgi intermediate compartment organization GO:0097111 IMP
    vesicle fusion GO:0006906 IBA
Subcellular Localization
    ER to Golgi transport vesicle membrane GO:0012507 IEA
    autophagosome membrane GO:0000421 IDA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IDA
    rough endoplasmic reticulum GO:0005791 IDA
    mitochondrion GO:0005739 IDA
    endoplasmic reticulum membrane GO:0005789 IDA
    integral component of membrane GO:0016021 IBA
    endomembrane system GO:0012505 IBA
    ER to Golgi transport vesicle GO:0030134 ISS
    smooth endoplasmic reticulum membrane GO:0030868 ISS
    lysosomal membrane GO:0005765 IDA
    endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116 IEA
    SNARE complex GO:0031201 IDA
    cytosol GO:0005829 ISS
    ER-mitochondrion membrane contact site GO:0044233 IDA
 Experiment description of studies that identified STX17 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for STX17
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STX5 6811
Co-purification Homo sapiens
2 SNAP29 9342
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which STX17 is involved
No pathways found





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