Gene description for DSG3
Gene name	desmoglein 3
Gene symbol	DSG3
Other names/aliases	CDHF6 PVA
Species	Homo sapiens
Database cross references - DSG3
ExoCarta	ExoCarta_1830
Vesiclepedia	VP_1830
Entrez Gene	1830
HGNC	3050
MIM	169615
UniProt	P32926
DSG3 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Prostate cancer cells	25844599
Urine	19056867

Gene ontology annotations for DSG3

Molecular Function     calcium ion binding GO:0005509 IBA     protein binding GO:0005515 IPI     protein dimerization activity GO:0046983 ISS Biological Process     desmosome assembly GO:0002159 IMP     actin filament organization GO:0007015 ISS     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA     negative regulation of cell migration GO:0030336 IMP     regulation of protein stability GO:0031647 IMP     adherens junction assembly GO:0034333 IMP     cell-cell adhesion GO:0098609 IBA     tight junction assembly GO:0120192 IMP     positive regulation of bicellular tight junction assembly GO:1903348 ISS     negative regulation of p38MAPK cascade GO:1903753 IMP     positive regulation of protein localization to adherens junction GO:1904704 IMP     positive regulation of protein localization to membrane GO:1905477 IMP Subcellular Localization     cornified envelope GO:0001533 TAS     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     cell-cell junction GO:0005911 IDA     bicellular tight junction GO:0005923 IEA     cell junction GO:0030054 IDA     desmosome GO:0030057 IBA     extracellular exosome GO:0070062 HDA     tight junction GO:0070160 ISS