Gene description for PPP2R2B
Gene name protein phosphatase 2, regulatory subunit B, beta
Gene symbol PPP2R2B
Other names/aliases B55BETA
PP2AB55BETA
PP2ABBETA
PP2APR55B
PP2APR55BETA
PR2AB55BETA
PR2ABBETA
PR2APR55BETA
PR52B
PR55-BETA
PR55BETA
SCA12
Species Homo sapiens
 Database cross references - PPP2R2B
ExoCarta ExoCarta_5521
Entrez Gene 5521
HGNC 9305
MIM 604325
UniProt Q00005  
 PPP2R2B identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PPP2R2B
Molecular Function
    protein binding GO:0005515 IPI
    protein phosphatase type 2A regulator activity GO:0008601 IEA
Biological Process
    apoptotic process GO:0006915 IEA
    signal transduction GO:0007165 IEA
    regulation of protein phosphatase type 2A activity GO:0034047 TAS
Subcellular Localization
    mitochondrial outer membrane GO:0005741 ISS
    cytoskeleton GO:0005856 IEA
    mitochondrion GO:0005739 ISS
    protein phosphatase type 2A complex GO:0000159 IEA
 Experiment description of studies that identified PPP2R2B in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPP2R2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PPP2R2B is involved
No pathways found





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