Experiment description of studies that identified FAM83H in exosomes

1 Experiment ID 207 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DKO-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 208 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Dks-8 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 209 MISEV standards ✘ Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DLD-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for FAM83H

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Csnk1d   Affinity Capture-MS Mus musculus 2 KRT73 319101 Affinity Capture-MS Homo sapiens 3 NOP9 161424 Affinity Capture-MS Homo sapiens 4 CSNK1A1 1452 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 P4HA2 8974 Affinity Capture-MS Homo sapiens 6 TRIM66   Affinity Capture-MS Homo sapiens 7 DNAJB2 3300 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 GAK 2580 Affinity Capture-MS Homo sapiens 9 KIF20A 10112 Affinity Capture-MS Homo sapiens 10 LOXL4 84171 Affinity Capture-MS Homo sapiens 11 LGALS3BP 3959 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 PER2   Affinity Capture-MS Homo sapiens 13 CDC16 8881 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 KIF23 9493 Affinity Capture-MS Homo sapiens 15 COPS5 10987 Affinity Capture-MS Homo sapiens 16 PRC1 9055 Affinity Capture-MS Homo sapiens 17 KRT40   Affinity Capture-MS Homo sapiens 18 BOD1L1 259282 Affinity Capture-MS Homo sapiens 19 KRT78 196374 Affinity Capture-MS Homo sapiens 20 HERC2 8924 Affinity Capture-MS Homo sapiens 21 TIAL1 7073 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 GTSE1 51512 Affinity Capture-MS Homo sapiens 23 CHTF18 63922 Affinity Capture-MS Homo sapiens 24 MRPL4 51073 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 NPAS1   Affinity Capture-MS Homo sapiens 26 NCK1 4690 Affinity Capture-MS Homo sapiens 27 C19orf45   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 KIF14 9928 Affinity Capture-MS Homo sapiens 29 NINL   Proximity Label-MS Homo sapiens 30 UNC45A 55898 Affinity Capture-Luminescence Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 CHMP4C 92421 Affinity Capture-MS Homo sapiens 32 KRT8 3856 Proximity Label-MS Homo sapiens 33 TSGA10IP   Affinity Capture-MS Homo sapiens 34 SOCS6   Affinity Capture-MS Homo sapiens 35 SEC13 6396 Affinity Capture-MS Homo sapiens 36 RBM4B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 Sec24c   Affinity Capture-MS Mus musculus 38 DNAJB8   Affinity Capture-MS Homo sapiens 39 DTNBP1   Affinity Capture-MS Homo sapiens 40 CDH1 999 Proximity Label-MS Homo sapiens 41 CHMP4B 128866 Affinity Capture-MS Homo sapiens 42 DDX54 79039 Affinity Capture-MS Homo sapiens 43 CSNK1E 1454 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 KRT2 3849 Affinity Capture-MS Homo sapiens 45 LYAR 55646 Affinity Capture-MS Homo sapiens 46 RABIF   Co-fractionation Homo sapiens 47 SDF4 51150 Affinity Capture-MS Homo sapiens 48 MYCL   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 GFAP 2670 Proximity Label-MS Homo sapiens 50 HSPB8 26353 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 ANLN 54443 Affinity Capture-MS Homo sapiens 52 DISC1 27185 Affinity Capture-MS Homo sapiens 53 BRF1   Affinity Capture-MS Homo sapiens 54 PPP2R2B 5521 Affinity Capture-MS Homo sapiens 55 KRT18 3875 Proximity Label-MS Homo sapiens 56 PPM1E   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 ECT2 1894 Affinity Capture-MS Homo sapiens 58 NCAPH2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 59 CRYAA 1409 Affinity Capture-MS Homo sapiens 60 SKP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 61 DUSP16   Affinity Capture-MS Homo sapiens 62 ORMDL1 94101 Affinity Capture-MS Homo sapiens 63 NXF2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 PPHLN1   Affinity Capture-MS Homo sapiens 65 MLF1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 Csnk1e   Affinity Capture-MS Mus musculus 67 CSNK1D 1453 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 68 NEFL 4747 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 NEFM 4741 Proximity Label-MS Homo sapiens 70 Uso1 56041 Affinity Capture-MS Mus musculus 71 NIN 51199 Proximity Label-MS Homo sapiens 72 SAV1   Affinity Capture-MS Homo sapiens 73 SEC16A 9919 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 74 CLTC 1213 Affinity Capture-MS Homo sapiens 75 CDC20B   Affinity Capture-MS Homo sapiens 76 KRT19 3880 Proximity Label-MS Homo sapiens 77 CCDC8   Affinity Capture-MS Homo sapiens 78 Cbx1   Affinity Capture-MS Mus musculus 79 MAP2K2 5605 Affinity Capture-MS Homo sapiens 80 FBXW11   Affinity Capture-MS Homo sapiens 81 TFDP3   Affinity Capture-MS Homo sapiens 82 CSNK1A1L 122011 Affinity Capture-MS Homo sapiens 83 APOBEC3D   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 84 TRIM52   Affinity Capture-MS Homo sapiens 85 WDR92 116143 Affinity Capture-MS Homo sapiens 86 Rbm8a   Affinity Capture-MS Mus musculus 87 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 88 FAM83F 113828 Affinity Capture-MS Homo sapiens 89 CAPZB 832 Affinity Capture-MS Homo sapiens 90 TSPYL1 7259 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 91 HSP90AA1 3320 Affinity Capture-MS Homo sapiens 92 NUP35 129401 Proximity Label-MS Homo sapiens 93 AARSD1 80755 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 94 NCK2 8440 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 95 C6orf141   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 96 FAM110D   Affinity Capture-MS Homo sapiens 97 RUSC1   Affinity Capture-MS Homo sapiens 98 CEP135   Proximity Label-MS Homo sapiens 99 GOT1 2805 Affinity Capture-MS Homo sapiens 100 SEC23B 10483 Affinity Capture-MS Homo sapiens 101 OR2A4 79541 Affinity Capture-MS Homo sapiens 102 CCDC96   Affinity Capture-MS Homo sapiens 103 CCR1   Affinity Capture-MS Homo sapiens 104 RPA3 6119 Proximity Label-MS Homo sapiens 105 SOHLH1   Affinity Capture-MS Homo sapiens View the network

Pathways in which FAM83H is involved

No pathways found