Gene ontology annotations for ORMDL1
Experiment description of studies that identified ORMDL1 in exosomes
1
Experiment ID
231
MISEV standards
✘
Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
232
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
233
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
5
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for ORMDL1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
TMEM35
Two-hybrid
Homo sapiens
2
MAGEA8
Affinity Capture-MS
Homo sapiens
3
ERGIC3
51614
Two-hybrid
Homo sapiens
4
TMEM143
Two-hybrid
Homo sapiens
5
GGACT
87769
Affinity Capture-MS
Homo sapiens
6
SLC30A8
Two-hybrid
Homo sapiens
7
SLC22A8
9376
Affinity Capture-MS
Homo sapiens
8
PTH1R
Affinity Capture-MS
Homo sapiens
9
TTYH1
Affinity Capture-MS
Homo sapiens
10
TTC33
Affinity Capture-MS
Homo sapiens
11
EBAG9
9166
Two-hybrid
Homo sapiens
12
TMEM63B
55362
Affinity Capture-MS
Homo sapiens
13
ZFYVE27
118813
Two-hybrid
Homo sapiens
14
TMEM52B
120939
Two-hybrid
Homo sapiens
15
EHHADH
1962
Two-hybrid
Homo sapiens
16
ASGR2
Two-hybrid
Homo sapiens
17
CRELD1
78987
Affinity Capture-MS
Homo sapiens
18
TMEM14B
Two-hybrid
Homo sapiens
19
SPTLC1
10558
Affinity Capture-MS
Homo sapiens
20
GPR12
Affinity Capture-MS
Homo sapiens
21
FPR1
Affinity Capture-MS
Homo sapiens
22
HSD17B11
51170
Two-hybrid
Homo sapiens
23
SLC5A6
8884
Affinity Capture-MS
Homo sapiens
24
EBP
Two-hybrid
Homo sapiens
25
KCNK4
Two-hybrid
Homo sapiens
26
AQP3
Affinity Capture-MS
Homo sapiens
27
FAM83H
286077
Affinity Capture-MS
Homo sapiens
28
SLC22A9
Affinity Capture-MS
Homo sapiens
29
APP
351
Reconstituted Complex
Homo sapiens
30
STOM
2040
Two-hybrid
Homo sapiens
31
GPR152
Two-hybrid
Homo sapiens
32
DCUN1D5
84259
Affinity Capture-MS
Homo sapiens
33
CPLX4
Two-hybrid
Homo sapiens
34
SLC10A1
Two-hybrid
Homo sapiens
35
CREB3L1
Two-hybrid
Homo sapiens
36
CREB3
Two-hybrid
Homo sapiens
37
SLC10A6
Two-hybrid
Homo sapiens
38
VMA21
Two-hybrid
Homo sapiens
39
PCNXL2
Two-hybrid
Homo sapiens
40
ARL13B
200894
Two-hybrid
Homo sapiens
41
SLC22A4
6583
Affinity Capture-MS
Homo sapiens
42
NEMF
9147
Affinity Capture-MS
Homo sapiens
43
SCN3B
Two-hybrid
Homo sapiens
44
PGRMC2
10424
Two-hybrid
Homo sapiens
45
ZDHHC15
158866
Two-hybrid
Homo sapiens
46
SLC2A9
Affinity Capture-MS
Homo sapiens
47
HIATL1
84641
Two-hybrid
Homo sapiens
48
TMEM56
Two-hybrid
Homo sapiens
49
Kif2a
16563
Affinity Capture-MS
Mus musculus
50
REEP4
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which ORMDL1 is involved