Gene description for CDH1
Gene name	cadherin 1, type 1, E-cadherin (epithelial)
Gene symbol	CDH1
Other names/aliases	Arc-1 CD324 CDHE ECAD LCAM UVO
Species	Homo sapiens
Database cross references - CDH1
ExoCarta	ExoCarta_999
Vesiclepedia	VP_999
Entrez Gene	999
HGNC	1748
MIM	192090
UniProt	P12830
CDH1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	17956143
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Keratinocytes	19530224
Keratinocytes	19530224
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Prostate cancer cells	25844599

Gene ontology annotations for CDH1

Molecular Function     protein phosphatase binding GO:0019903 IEA     protein binding GO:0005515 IPI     gamma-catenin binding GO:0045295 IPI     GTPase activating protein binding GO:0032794 IPI     ankyrin binding GO:0030506 IPI     protein domain specific binding GO:0019904 IEA     glycoprotein binding GO:0001948 IPI     cell adhesion molecule binding GO:0050839 NAS     calcium ion binding GO:0005509 IEA     beta-catenin binding GO:0008013 IDA Biological Process     cellular response to indole-3-methanol GO:0071681 IDA     positive regulation of transcription, DNA-templated GO:0045893 IDA     single organismal cell-cell adhesion GO:0016337 IDA     regulation of protein localization to cell surface GO:2000008 IEA     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 NAS     extracellular matrix organization GO:0030198 TAS     negative regulation of cell-cell adhesion GO:0022408 IMP     small GTPase mediated signal transduction GO:0007264 TAS     sensory perception of sound GO:0007605 IEA     pituitary gland development GO:0021983 IEA     cellular response to lithium ion GO:0071285 IDA     regulation of branching involved in salivary gland morphogenesis GO:0060693 IEA     adherens junction organization GO:0034332 TAS     positive regulation of transcription factor import into nucleus GO:0042993 IDA     negative regulation of epithelial cell proliferation GO:0050680 IEA     cochlea development GO:0090102 IEA     trophectodermal cell differentiation GO:0001829 IEA     bicellular tight junction assembly GO:0070830 IEA     establishment of protein localization to plasma membrane GO:0090002 IMP     apoptotic process GO:0006915 TAS     synapse assembly GO:0007416 IEA     protein homooligomerization GO:0051260 IEA     neuron projection development GO:0031175 IEA     salivary gland cavitation GO:0060662 IEA     cell junction assembly GO:0034329 TAS     calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339 IEA     protein metabolic process GO:0019538 IEA     regulation of water loss via skin GO:0033561 IEA     regulation of neuron migration GO:2001222 IEA     protein localization to plasma membrane GO:0072659 IDA     response to drug GO:0042493 IEA     regulation of immune response GO:0050776 TAS     extracellular matrix disassembly GO:0022617 TAS     intestinal epithelial cell development GO:0060576 IEA     cellular component disassembly involved in execution phase of apoptosis GO:0006921 TAS     epithelial cell morphogenesis GO:0003382 IEA     response to toxic substance GO:0009636 IEA     programmed cell death GO:0012501 TAS     cellular response to amino acid stimulus GO:0071230 IEA     regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 IEA     cell-cell junction organization GO:0045216 TAS     negative regulation of canonical Wnt signaling pathway GO:0090090 IEA Subcellular Localization     cell junction GO:0030054 TAS     lateral plasma membrane GO:0016328 IDA     lamellipodium GO:0030027 IDA     cytoplasmic side of plasma membrane GO:0009898 IDA     flotillin complex GO:0016600 IDA     cell surface GO:0009986 IEA     Schmidt-Lanterman incisure GO:0043220 IEA     extracellular exosome GO:0070062 IDA     trans-Golgi network GO:0005802 IMP     aggresome GO:0016235 IDA     focal adhesion GO:0005925 IDA     axon terminus GO:0043679 IEA     integral component of membrane GO:0016021 IDA     cortical actin cytoskeleton GO:0030864 IDA     cell-cell adherens junction GO:0005913 IDA     lateral loop GO:0043219 IEA     actin cytoskeleton GO:0015629 IDA     perinuclear region of cytoplasm GO:0048471 IDA     apical junction complex GO:0043296 IDA     node of Ranvier GO:0033268 IEA     extracellular region GO:0005576 TAS     plasma membrane GO:0005886 TAS     basolateral plasma membrane GO:0016323 IEA     apical part of cell GO:0045177 IEA     cytoplasm GO:0005737 IDA     catenin complex GO:0016342 IDA     endosome GO:0005768 IEA