Experiment description of studies that identified NEDD9 in exosomes

1 Experiment ID 224 ISEV standards ✔ EM|AFM EV Biophysical techniques ✔ Alix|TSG101 EV Cytosolic markers ✔ CD63|CD81 EV Membrane markers ✔ GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for NEDD9

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ELSPBP1   Two-hybrid Homo sapiens 2 SH2D3C   Affinity Capture-Western Homo sapiens 3 NCK1 4690 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 4 PXN   Invivo Homo sapiens 5 ZYX 7791 Invivo Homo sapiens Two-hybrid Homo sapiens Invitro Homo sapiens 6 NEDD9 4739 Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 7 BCAR1 9564 Invivo Homo sapiens Invivo Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 8 LCK 3932 Affinity Capture-Western Homo sapiens 9 SMAD1   Invivo Homo sapiens 10 ABL1 25 Invivo Homo sapiens Invitro Homo sapiens Affinity Capture-Western Homo sapiens 11 PTK2 5747 Invivo Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 12 LYN 4067 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 13 BCAR3   Affinity Capture-Western Homo sapiens 14 PTPN12   Reconstituted Complex Homo sapiens 15 TRIP6   Two-hybrid Homo sapiens Invivo Homo sapiens Two-hybrid Homo sapiens 16 CDH1 999 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 17 SMAD3   Reconstituted Complex Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 18 CRKL 1399 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 19 CRK 1398 Invivo Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Invitro Homo sapiens Affinity Capture-Western Homo sapiens 20 PTK2B 2185 Affinity Capture-Western Homo sapiens 21 SMAD2 4087 Invivo Homo sapiens 22 FYN 2534 Affinity Capture-Western Homo sapiens 23 MICAL1 64780 Invivo Homo sapiens Invitro Homo sapiens Invivo Homo sapiens Invitro Homo sapiens 24 RAPGEF1 2889 Invivo Homo sapiens Affinity Capture-Western Homo sapiens 25 ITCH 83737 Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 26 ID2   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens View the network

Pathways in which NEDD9 is involved

No pathways found