Experiment description of studies that identified NEDD9 in sEVs

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for NEDD9

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NOTCH2NL 388677 Two-hybrid Homo sapiens 2 TRIP6 7205 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 3 PRAM1   Two-hybrid Homo sapiens 4 MED19   Two-hybrid Homo sapiens 5 TFCP2 7024 Two-hybrid Homo sapiens 6 NOTCH3 4854 Reconstituted Complex Homo sapiens 7 NCK1 4690 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 8 BCAR3 8412 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 9 RBPMS 11030 Two-hybrid Homo sapiens 10 PRR20A   Two-hybrid Homo sapiens 11 DMRTB1   Two-hybrid Homo sapiens 12 WWOX 51741 Two-hybrid Homo sapiens 13 C19orf54   Two-hybrid Homo sapiens 14 ZYX 7791 Two-hybrid Homo sapiens 15 KRT32   Two-hybrid Homo sapiens 16 NEDD9 4739 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 17 BANP   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 18 NFKBIA   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 19 SH2D3C 10044 Affinity Capture-Western Homo sapiens 20 BCAR1 9564 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 21 CDC42EP2   Two-hybrid Homo sapiens 22 NBPF19   Two-hybrid Homo sapiens 23 TINAG   Affinity Capture-MS Homo sapiens 24 LCK 3932 Affinity Capture-Western Homo sapiens 25 LHX8   Two-hybrid Homo sapiens 26 ABL1 25 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 27 KLHL18   Affinity Capture-MS Homo sapiens 28 PTK2 5747 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 29 HOXA1 3198 Two-hybrid Homo sapiens 30 FAM102A   Two-hybrid Homo sapiens 31 FAM168B 130074 Two-hybrid Homo sapiens 32 APP 351 Reconstituted Complex Homo sapiens 33 LYN 4067 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 34 TRAF2 7186 Two-hybrid Homo sapiens 35 SMAD1 4086 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 36 DPPA4   Two-hybrid Homo sapiens 37 PIK3R3 8503 Two-hybrid Homo sapiens 38 RHEB 6009 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 TBX19   Two-hybrid Homo sapiens 40 FYN 2534 Affinity Capture-Western Homo sapiens 41 AURKA 6790 Reconstituted Complex Homo sapiens 42 TRIM23 373 Two-hybrid Homo sapiens 43 NAB2 4665 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 44 PTPN12 5782 Reconstituted Complex Homo sapiens 45 CRKL 1399 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 46 PXN 5829 Affinity Capture-Western Homo sapiens 47 RFX6   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 48 SMAD3 4088 Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 49 PTK2B 2185 Affinity Capture-Western Homo sapiens 50 TRIM27   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 51 PIK3CA 5290 Two-hybrid Homo sapiens 52 FZR1   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 53 SMAD2 4087 Affinity Capture-Western Homo sapiens 54 FOSB   Two-hybrid Homo sapiens 55 SMURF2 64750 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 56 MICAL1 64780 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 57 RAPGEF1 2889 Affinity Capture-Western Homo sapiens 58 INCA1   Two-hybrid Homo sapiens 59 ITCH 83737 Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 60 REL 5966 Two-hybrid Homo sapiens 61 C9orf41   Affinity Capture-MS Homo sapiens 62 EXOSC8   Two-hybrid Homo sapiens 63 CTTN 2017 Affinity Capture-Western Homo sapiens 64 ID2   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 65 CRK 1398 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens View the network

Pathways in which NEDD9 is involved

No pathways found