Gene description for HOXA1
Gene name homeobox A1
Gene symbol HOXA1
Other names/aliases BSAS
HOX1
HOX1F
Species Homo sapiens
 Database cross references - HOXA1
ExoCarta ExoCarta_3198
Vesiclepedia VP_3198
Entrez Gene 3198
HGNC 5099
MIM 142955
UniProt P49639  
 HOXA1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for HOXA1
Molecular Function
    protein binding GO:0005515 IPI
    sequence-specific DNA binding GO:0043565 IEA
Biological Process
    central nervous system neuron differentiation GO:0021953 IEA
    optokinetic behavior GO:0007634 IDA
    cochlea development GO:0090102 IMP
    anatomical structure morphogenesis GO:0009653 IMP
    facial nucleus development GO:0021754 IEA
    cochlea morphogenesis GO:0090103 IMP
    artery development GO:0060840 IMP
    regulation of behavior GO:0050795 IDA
    cognition GO:0050890 IDA
    inner ear development GO:0048839 IMP
    rhombomere 4 development GO:0021570 IEA
    neuromuscular process GO:0050905 IDA
    transcription, DNA-templated GO:0006351 IEA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA
    multicellular organismal development GO:0007275 TAS
    rhombomere 3 development GO:0021569 IEA
    semicircular canal formation GO:0060876 IMP
    motor neuron axon guidance GO:0008045 IEA
    anterior/posterior pattern specification GO:0009952 IEA
    outer ear morphogenesis GO:0042473 IDA
    sensory perception of sound GO:0007605 IDA
    embryonic neurocranium morphogenesis GO:0048702 IMP
    facial nerve structural organization GO:0021612 IEA
    rhombomere 5 development GO:0021571 IEA
    artery morphogenesis GO:0048844 IMP
    abducens nerve formation GO:0021599 IMP
    cellular response to retinoic acid GO:0071300 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified HOXA1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
EV Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
EV Enriched markers
✔
Canx
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for HOXA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LPXN 9404
Two-hybrid Homo sapiens
2 PKNOX1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
3 CHIC2 26511
Two-hybrid Homo sapiens
4 KRTAP4-12  
Two-hybrid Homo sapiens
5 GRN 2896
Two-hybrid Homo sapiens
6 MDFI  
Two-hybrid Homo sapiens
7 TRIP6  
Two-hybrid Homo sapiens
8 PLSCR1 5359
Two-hybrid Homo sapiens
9 MGC2650  
Two-hybrid Homo sapiens
10 EFEMP2 30008
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which HOXA1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here