Gene description for INO80B
Gene name INO80 complex subunit B
Gene symbol INO80B
Other names/aliases HMGA1L4
HMGIYL4
IES2
PAP-1BP
PAPA-1
ZNHIT4
hIes2
Species Homo sapiens
 Database cross references - INO80B
ExoCarta ExoCarta_83444
Entrez Gene 83444
HGNC 13324
UniProt Q9C086  
 INO80B identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for INO80B
Molecular Function
    metal ion binding GO:0046872 IEA
    protein binding GO:0005515 IPI
Biological Process
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    chromatin remodeling GO:0006338 IEA
    DNA repair GO:0006281 IEA
    DNA recombination GO:0006310 IEA
Subcellular Localization
    Ino80 complex GO:0031011 IDA
    nucleolus GO:0005730 IEA
    plasma membrane GO:0005886 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified INO80B in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for INO80B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD81 975
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which INO80B is involved
No pathways found





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