Gene description for AES
Gene name	amino-terminal enhancer of split
Gene symbol	AES
Other names/aliases	AES-1 AES-2 ESP1 GRG GRG5 Grg-5 TLE5
Species	Homo sapiens
Database cross references - AES
ExoCarta	ExoCarta_166
Vesiclepedia	VP_166
Entrez Gene	166
HGNC	307
MIM	600188
UniProt	Q08117
AES identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for AES

Molecular Function     transcription corepressor activity GO:0003714 IDA     transcription corepressor activity GO:0003714 IPI     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IPI Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IMP     skeletal system development GO:0001501 IEA     negative regulation of gene expression GO:0010629 IMP     Wnt signaling pathway GO:0016055 IEA     negative regulation of protein binding GO:0032091 IDA     regulation of growth GO:0040008 IEA     negative regulation of DNA-templated transcription GO:0045892 IDA     negative regulation of response to cytokine stimulus GO:0060761 IMP     response to interleukin-1 GO:0070555 IDA     negative regulation of canonical Wnt signaling pathway GO:0090090 IDA     positive regulation of anoikis GO:2000210 IMP Subcellular Localization     nucleus GO:0005634 IDA