Gene description for RIMBP3
Gene name RIMS binding protein 3
Gene symbol RIMBP3
Other names/aliases RIM-BP3
RIM-BP3.1
RIM-BP3.A
RIMBP3.1
RIMBP3A
Species Homo sapiens
 Database cross references - RIMBP3
ExoCarta ExoCarta_85376
Vesiclepedia VP_85376
Entrez Gene 85376
HGNC 29344
MIM 612699
UniProt Q9UFD9  
 RIMBP3 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for RIMBP3
Molecular Function
    protein binding GO:0005515 IPI
    benzodiazepine receptor binding GO:0030156 IBA
Biological Process
    neuromuscular synaptic transmission GO:0007274 IBA
    spermatid development GO:0007286 IBA
    fertilization GO:0009566 IBA
Subcellular Localization
    manchette GO:0002177 IBA
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified RIMBP3 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for RIMBP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AES 166
Two-hybrid Homo sapiens
2 EFHC1  
Two-hybrid Homo sapiens
3 CREB5 9586
Two-hybrid Homo sapiens
4 MVP 9961
Two-hybrid Homo sapiens
5 NOXA1  
Two-hybrid Homo sapiens
6 DGCR6L  
Two-hybrid Homo sapiens
7 FANCL 55120
Two-hybrid Homo sapiens
8 AQP1 358
Two-hybrid Homo sapiens
9 CATSPER1  
Two-hybrid Homo sapiens
10 TRAF3IP2  
Two-hybrid Homo sapiens
11 PRKAB2 5565
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
12 ARNT2  
Two-hybrid Homo sapiens
13 PRKAA1 5562
Two-hybrid Homo sapiens
14 POLR1C 9533
Two-hybrid Homo sapiens
15 HOOK1  
Proximity Label-MS Homo sapiens
16 ZNF488  
Two-hybrid Homo sapiens
17 PPIL1 51645
Two-hybrid Homo sapiens
18 DGCR6  
Two-hybrid Homo sapiens
19 DTX2 113878
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
20 CTBP2 1488
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RIMBP3 is involved
No pathways found





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