Gene description for CTBP2
Gene name
C-terminal binding protein 2
Gene symbol
CTBP2
Other names/aliases
-
Species
Homo sapiens
Database cross references - CTBP2
ExoCarta
ExoCarta_1488
Entrez Gene
1488
HGNC
2495
MIM
602619
UniProt
P56545
CTBP2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells
Unpublished / Not applicable
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for CTBP2
Experiment description of studies that identified CTBP2 in exosomes
1
Experiment ID
126
ISEV standards
✘
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
2
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for CTBP2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PSMF1
Two-hybrid
Homo sapiens
2
CBX4
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
3
RAI2
Two-hybrid
Homo sapiens
4
NRIP1
8204
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
5
ZFPM2
Invitro
Homo sapiens
Invivo
Homo sapiens
6
TEAD3
Two-hybrid
Homo sapiens
7
FTS
Two-hybrid
Homo sapiens
8
KLF3
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
9
FHL3
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-MS
Homo sapiens
10
NOL4
Two-hybrid
Homo sapiens
11
BAZ2B
Two-hybrid
Homo sapiens
12
Pc1
Two-hybrid
8355
Reconstituted Complex
8355
13
ELAC2
Affinity Capture-MS
Homo sapiens
14
KLF8
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
15
MDM2
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
16
CTBP1
1487
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
17
SOX6
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
18
TGIF
Two-hybrid
Homo sapiens
19
CTBP2
1488
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which CTBP2 is involved