Gene description for KEAP1
Gene name	kelch-like ECH-associated protein 1
Gene symbol	KEAP1
Other names/aliases	INrf2 KLHL19
Species	Homo sapiens
Database cross references - KEAP1
ExoCarta	ExoCarta_9817
Entrez Gene	9817
HGNC	23177
MIM	606016
UniProt	Q14145
KEAP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for KEAP1

Molecular Function     transcription factor binding GO:0008134 IPI     protein binding GO:0005515 IPI Biological Process     regulation of epidermal cell differentiation GO:0045604 IEA     cellular response to interleukin-4 GO:0071353 IEA     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 TAS     protein ubiquitination GO:0016567 IMP     negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 TAS     in utero embryonic development GO:0001701 IEA     proteasomal ubiquitin-independent protein catabolic process GO:0010499 IDA     transcription, DNA-templated GO:0006351 IEA     positive regulation of cellular protein metabolic process GO:0032270 IMP Subcellular Localization     cytosol GO:0005829 TAS     nucleoplasm GO:0005654 IDA     microtubule organizing center GO:0005815 IDA     midbody GO:0030496 IDA     cytoplasm GO:0005737 IDA     Cul3-RING ubiquitin ligase complex GO:0031463 IDA     endoplasmic reticulum GO:0005783 IEA