Gene description for ARCN1
Gene name archain 1
Gene symbol ARCN1
Other names/aliases COPD
Species Homo sapiens
 Database cross references - ARCN1
ExoCarta ExoCarta_372
Entrez Gene 372
HGNC 649
MIM 600820
UniProt P48444  
 ARCN1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ARCN1
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    adult locomotory behavior GO:0008344 IEA
    COPI coating of Golgi vesicle GO:0048205 TAS
    cerebellar Purkinje cell layer maturation GO:0021691 IEA
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 TAS
    membrane organization GO:0061024 TAS
    intracellular protein transport GO:0006886 IEA
    pigmentation GO:0043473 IEA
Subcellular Localization
    clathrin adaptor complex GO:0030131 IEA
    membrane GO:0016020 IDA
    Golgi apparatus GO:0005794 IDA
    cytosol GO:0005829 TAS
    cytoplasm GO:0005737 IDA
    COPI vesicle coat GO:0030126 ISS
    intracellular membrane-bounded organelle GO:0043231 IDA
    endoplasmic reticulum GO:0005783 IEA
 Experiment description of studies that identified ARCN1 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARCN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COPB1 1315
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which ARCN1 is involved
PathwayEvidenceSource
COPI Mediated Transport TAS Reactome





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