Gene description for ERGIC2
Gene name ERGIC and golgi 2
Gene symbol ERGIC2
Other names/aliases CDA14
Erv41
PTX1
cd002
Species Homo sapiens
 Database cross references - ERGIC2
ExoCarta ExoCarta_51290
Entrez Gene 51290
HGNC 30208
MIM 612236
UniProt Q96RQ1  
 ERGIC2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for ERGIC2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    vesicle-mediated transport GO:0016192 IEA
Subcellular Localization
    endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116 IEA
    Golgi apparatus GO:0005794 IEA
    nucleus GO:0005634 IDA
    integral component of membrane GO:0016021 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified ERGIC2 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ERGIC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ERGIC2 is involved
No pathways found





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