Gene description for TMEM209
Gene name transmembrane protein 209
Gene symbol TMEM209
Other names/aliases NET31
Species Homo sapiens
 Database cross references - TMEM209
ExoCarta ExoCarta_84928
Vesiclepedia VP_84928
Entrez Gene 84928
HGNC 21898
UniProt Q96SK2  
 TMEM209 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TMEM209
Subcellular Localization
    nuclear envelope GO:0005635 IEA
    Golgi apparatus GO:0005794 IEA
    membrane GO:0016020 IBA
 Experiment description of studies that identified TMEM209 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TMEM209
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAMP3  
Affinity Capture-MS Homo sapiens
2 GJD3  
Proximity Label-MS Homo sapiens
3 METTL7A 25840
Proximity Label-MS Homo sapiens
4 Rcc1  
Affinity Capture-MS Mus musculus
5 GJA1 2697
Proximity Label-MS Homo sapiens
6 DYNC1I2 1781
Proximity Label-MS Homo sapiens
7 KPNB1 3837
Affinity Capture-MS Homo sapiens
8 TMEM184A  
Affinity Capture-MS Homo sapiens
9 GFAP 2670
Proximity Label-MS Homo sapiens
10 SLC2A1 6513
Affinity Capture-MS Homo sapiens
11 FPR1  
Affinity Capture-MS Homo sapiens
12 HSD17B11 51170
Proximity Label-MS Homo sapiens
13 LAMP2 3920
Proximity Label-MS Homo sapiens
14 DNAJC25 548645
Proximity Label-MS Homo sapiens
15 PTPN1 5770
Proximity Label-MS Homo sapiens
16 STX4 6810
Proximity Label-MS Homo sapiens
17 FFAR1  
Affinity Capture-MS Homo sapiens
18 FIS1 51024
Proximity Label-MS Homo sapiens
19 CARKD 55739
Affinity Capture-MS Homo sapiens
20 NUP153 9972
Affinity Capture-MS Homo sapiens
21 GPR55  
Affinity Capture-MS Homo sapiens
22 SSR1 6745
Proximity Label-MS Homo sapiens
23 MARCH5  
Proximity Label-MS Homo sapiens
24 SLC25A46 91137
Proximity Label-MS Homo sapiens
25 RAB35 11021
Proximity Label-MS Homo sapiens
26 MARCKS 4082
Proximity Label-MS Homo sapiens
27 LMAN1 3998
Proximity Label-MS Homo sapiens
28 NUP155 9631
Proximity Label-MS Homo sapiens
29 KIAA1715 80856
Proximity Label-MS Homo sapiens
30 PXMP2  
Proximity Label-MS Homo sapiens
31 RAB5A 5868
Proximity Label-MS Homo sapiens
32 LMNB1 4001
Proximity Label-MS Homo sapiens
33 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
34 ATG9A 79065
Proximity Label-MS Homo sapiens
35 EMD 2010
Proximity Label-MS Homo sapiens
36 UBE2I 7329
Affinity Capture-MS Homo sapiens
37 TUBA1C 84790
Affinity Capture-MS Homo sapiens
38 GPR182  
Affinity Capture-MS Homo sapiens
39 DTX2 113878
Proximity Label-MS Homo sapiens
40 FLRT1  
Affinity Capture-MS Homo sapiens
41 RAB7A 7879
Proximity Label-MS Homo sapiens
42 RPN1 6184
Proximity Label-MS Homo sapiens
43 Ube2i  
Affinity Capture-MS Mus musculus
44 RHOT2 89941
Proximity Label-MS Homo sapiens
45 ELOVL5 60481
Proximity Label-MS Homo sapiens
46 SEC61B 10952
Proximity Label-MS Homo sapiens
47 Nup155  
Affinity Capture-MS Mus musculus
48 RMDN3 55177
Proximity Label-MS Homo sapiens
49 REEP5 7905
Proximity Label-MS Homo sapiens
50 BCAP31 10134
Proximity Label-MS Homo sapiens
51 APLNR  
Affinity Capture-MS Homo sapiens
52 RPN2 6185
Proximity Label-MS Homo sapiens
53 Nup98  
Affinity Capture-MS Mus musculus
54 MUS81  
Synthetic Growth Defect Homo sapiens
55 LRRC59 55379
Proximity Label-MS Homo sapiens
56 PANX1 24145
Proximity Label-MS Homo sapiens
57 DUOXA2  
Affinity Capture-MS Homo sapiens
58 LAMP1 3916
Proximity Label-MS Homo sapiens
59 MGARP  
Affinity Capture-MS Homo sapiens
60 HSD3B7 80270
Proximity Label-MS Homo sapiens
61 CUL3 8452
Affinity Capture-MS Homo sapiens
62 STIM1 6786
Proximity Label-MS Homo sapiens
63 ARF6 382
Proximity Label-MS Homo sapiens
64 AQP3  
Affinity Capture-MS Homo sapiens
65 SNX27 81609
Affinity Capture-MS Homo sapiens
66 Nup107  
Affinity Capture-MS Mus musculus
67 RPA3 6119
Proximity Label-MS Homo sapiens
68 ATP2A1 487
Proximity Label-MS Homo sapiens
69 GPR45  
Affinity Capture-MS Homo sapiens
70 RAB9A 9367
Proximity Label-MS Homo sapiens
71 BAP1 8314
Negative Genetic Homo sapiens
72 SEH1L 81929
Affinity Capture-MS Homo sapiens
73 LMNA 4000
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
74 RNF43  
Proximity Label-MS Homo sapiens
75 NAAA  
Affinity Capture-MS Homo sapiens
76 SIRT6  
Affinity Capture-MS Homo sapiens
77 MFSD4  
Affinity Capture-MS Homo sapiens
78 TNFSF14  
Affinity Capture-MS Homo sapiens
79 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
80 NUP35 129401
Proximity Label-MS Homo sapiens
81 ERGIC1 57222
Proximity Label-MS Homo sapiens
82 Tuba3a 22144
Affinity Capture-MS Mus musculus
83 ERGIC2 51290
Proximity Label-MS Homo sapiens
84 NUP107 57122
Affinity Capture-MS Homo sapiens
85 PSMA5 5686
Affinity Capture-MS Homo sapiens
86 SEC62 7095
Proximity Label-MS Homo sapiens
87 B3GAT1  
Proximity Label-MS Homo sapiens
88 NAB2 4665
Affinity Capture-MS Homo sapiens
89 CEP135  
Proximity Label-MS Homo sapiens
90 Ranbp2  
Affinity Capture-MS Mus musculus
91 DNAJC1 64215
Proximity Label-MS Homo sapiens
92 VIPR1  
Affinity Capture-MS Homo sapiens
93 RAB5C 5878
Proximity Label-MS Homo sapiens
94 C9orf72  
Affinity Capture-MS Homo sapiens
95 CKAP4 10970
Proximity Label-MS Homo sapiens
96 SLC1A1 6505
Affinity Capture-MS Homo sapiens
97 Smn1 20595
Affinity Capture-MS Mus musculus
98 DERL1 79139
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TMEM209 is involved
No pathways found





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