Gene description for UBE2I
Gene name ubiquitin-conjugating enzyme E2I
Gene symbol UBE2I
Other names/aliases C358B7.1
P18
UBC9
Species Homo sapiens
 Database cross references - UBE2I
ExoCarta ExoCarta_7329
Vesiclepedia VP_7329
Entrez Gene 7329
HGNC 12485
MIM 601661
UniProt P63279  
 UBE2I identified in sEVs derived from the following tissue/cell type
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocytes 26054723    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for UBE2I
Molecular Function
    transcription coregulator binding GO:0001221 IPI
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    transcription factor binding GO:0008134 IPI
    SUMO transferase activity GO:0019789 EXP
    SUMO transferase activity GO:0019789 TAS
    enzyme binding GO:0019899 IPI
    small protein activating enzyme binding GO:0044388 IPI
    SUMO conjugating enzyme activity GO:0061656 IBA
    SUMO conjugating enzyme activity GO:0061656 IDA
    RING-like zinc finger domain binding GO:0071535 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    negative regulation of transcription by RNA polymerase II GO:0000122 TAS
    ubiquitin-dependent protein catabolic process GO:0006511 TAS
    chromosome segregation GO:0007059 IEA
    mitotic nuclear membrane reassembly GO:0007084 TAS
    protein sumoylation GO:0016925 IBA
    protein sumoylation GO:0016925 IDA
    protein sumoylation GO:0016925 IEA
    protein sumoylation GO:0016925 IMP
    protein sumoylation GO:0016925 TAS
    positive regulation of cell migration GO:0030335 IMP
    protein modification process GO:0036211 TAS
    negative regulation of DNA-templated transcription GO:0045892 IDA
    nuclear export GO:0051168 EXP
    cell division GO:0051301 IEA
    positive regulation of SUMO transferase activity GO:1903755 IDA
Subcellular Localization
    synaptonemal complex GO:0000795 TAS
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nuclear envelope GO:0005635 TAS
    nuclear pore GO:0005643 NAS
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    PML body GO:0016605 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
    SUMO ligase complex GO:0106068 IPI
    transferase complex GO:1990234 IDA
 Experiment description of studies that identified UBE2I in sEVs
1
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UBE2I
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LCE1F  
Two-hybrid Homo sapiens
2 HDAC4  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
3 ZG16  
Two-hybrid Homo sapiens
4 CSGALNACT2 55454
Two-hybrid Homo sapiens
5 ZNF24  
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
6 ETV6  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
7 PRPF8 10594
Biochemical Activity Homo sapiens
8 WNK1 65125
Biochemical Activity Homo sapiens
9 TOP2B 7155
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
10 TSHZ2  
Biochemical Activity Homo sapiens
11 NFATC1 4772
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
12 KRTAP5-4  
Two-hybrid Homo sapiens
13 EDARADD  
Two-hybrid Homo sapiens
14 BRCA1 672
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
15 SLC2A1 6513
Affinity Capture-Western Homo sapiens
16 SETX  
Two-hybrid Homo sapiens
17 RHOXF2  
Two-hybrid Homo sapiens
18 PRPF40A 55660
Two-hybrid Homo sapiens
19 PARK7 11315
Two-hybrid Homo sapiens
20 PRKDC 5591
Biochemical Activity Homo sapiens
21 KCNIP3  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
22 APEX1 328
Two-hybrid Homo sapiens
23 LMO2  
Two-hybrid Homo sapiens
24 MAP3K5 4217
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
25 STX1A 6804
Two-hybrid Homo sapiens
26 PELI1 57162
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
27 UBE2K 3093
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
28 WT1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
29 C18orf25 147339
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
30 NUP153 9972
Affinity Capture-MS Homo sapiens
31 PIAS4  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
32 ZMYND11 10771
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
33 MARCH5  
Two-hybrid Homo sapiens
34 NOP56 10528
Biochemical Activity Homo sapiens
35 RIPK2  
Two-hybrid Homo sapiens
36 EIF2B1 1967
Two-hybrid Homo sapiens
37 RBM14 10432
Biochemical Activity Homo sapiens
38 EXOSC9 5393
Two-hybrid Homo sapiens
39 TFAP2A  
Two-hybrid Homo sapiens
40 AURKA 6790
Biochemical Activity Homo sapiens
41 ATF7IP 55729
Two-hybrid Homo sapiens
42 MED7  
Biochemical Activity Homo sapiens
43 RNF4 6047
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
44 SKI 6497
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
45 SAE1 10055
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 CTBP1 1487
Affinity Capture-Western Homo sapiens
47 CREBL2  
Two-hybrid Homo sapiens
48 MAPRE1 22919
Affinity Capture-MS Homo sapiens
49 FANCM 57697
Biochemical Activity Homo sapiens
50 Rangap1  
Co-crystal Structure Mus musculus
Reconstituted Complex Mus musculus
Biochemical Activity Mus musculus
Biochemical Activity Mus musculus
Biochemical Activity Mus musculus
51 HDAC7  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
52 CARM1 10498
Two-hybrid Homo sapiens
53 FOXL2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
54 MYH9 4627
Biochemical Activity Homo sapiens
55 TRIM21 6737
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
56 SLX4  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
57 Hipk2  
Biochemical Activity Mus musculus
58 ANAPC4 29945
Biochemical Activity Homo sapiens
59 WHSC1L1  
Two-hybrid Homo sapiens
60 VENTX  
Two-hybrid Homo sapiens
61 ETV1  
Biochemical Activity Homo sapiens
62 SND1 27044
Biochemical Activity Homo sapiens
63 STX2 2054
Two-hybrid Homo sapiens
64 TRIM63  
Two-hybrid Homo sapiens
65 SP100 6672
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
66 ATXN1 6310
Two-hybrid Homo sapiens
67 PLAGL1  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
68 BCAM 4059
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
69 RNF40 9810
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
70 RNF144B  
Two-hybrid Homo sapiens
71 SUGP1  
Co-fractionation Homo sapiens
72 STMN2  
Biochemical Activity Homo sapiens
73 LMNB1 4001
Two-hybrid Homo sapiens
74 SRSF4 6429
Two-hybrid Homo sapiens
75 RNF128  
Two-hybrid Homo sapiens
76 UBQLN2 29978
Two-hybrid Homo sapiens
77 ANXA1 301
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
78 TXLNB  
Two-hybrid Homo sapiens
79 TNFRSF1A 7132
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
80 CUL3 8452
Affinity Capture-MS Homo sapiens
81 DES 1674
Two-hybrid Homo sapiens
82 BHLHE40  
Two-hybrid Homo sapiens
83 AAAS 8086
Affinity Capture-MS Homo sapiens
84 HMBOX1  
Two-hybrid Homo sapiens
85 PRPSAP1 5635
Two-hybrid Homo sapiens
86 XBP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
87 FADD 8772
Two-hybrid Homo sapiens
88 THRA  
Biochemical Activity Homo sapiens
89 TBP  
Biochemical Activity Homo sapiens
90 HIST1H1B 3009
Cross-Linking-MS (XL-MS) Homo sapiens
91 UBA2 10054
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 STAT1 6772
Biochemical Activity Homo sapiens
93 PHC1  
Two-hybrid Homo sapiens
94 GOLGA1  
Two-hybrid Homo sapiens
95 ETS1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
96 TBL1X 6907
Biochemical Activity Homo sapiens
97 TAF1  
Biochemical Activity Homo sapiens
98 SUMO1P1  
Two-hybrid Homo sapiens
99 CTNNA1 1495
Biochemical Activity Homo sapiens
100 PDZK1 5174
Two-hybrid Homo sapiens
101 CDKN1B 1027
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
102 KRT19 3880
Two-hybrid Homo sapiens
103 GRIP1  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
104 THY1 7070
Co-fractionation Homo sapiens
105 CAMK2G 818
Two-hybrid Homo sapiens
106 ZCCHC12  
Two-hybrid Homo sapiens
107 MALL  
Two-hybrid Homo sapiens
108 KCNA5  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
109 GOLGB1 2804
Two-hybrid Homo sapiens
110 BANP  
Two-hybrid Homo sapiens
111 DTX3L 151636
Two-hybrid Homo sapiens
112 SKIL  
Two-hybrid Homo sapiens
113 USP25  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
114 LNX2  
Two-hybrid Homo sapiens
115 PCGF2 7703
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
116 RBM25 58517
Biochemical Activity Homo sapiens
117 MTA1 9112
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
118 TCERG1 10915
Biochemical Activity Homo sapiens
119 ATXN7  
Affinity Capture-Western Homo sapiens
120 CDC37 11140
Biochemical Activity Homo sapiens
121 NR3C2  
Two-hybrid Homo sapiens
122 TKT 7086
Co-fractionation Homo sapiens
123 SALL1 6299
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
124 SIRT1  
Biochemical Activity Homo sapiens
125 LATS1  
Biochemical Activity Homo sapiens
126 DRG1 4733
Biochemical Activity Homo sapiens
127 TIGD3  
Two-hybrid Homo sapiens
128 WWP2 11060
Biochemical Activity Homo sapiens
129 TCF4  
Biochemical Activity Homo sapiens
130 BCL2  
Affinity Capture-Western Homo sapiens
131 PHACTR4 65979
Affinity Capture-MS Homo sapiens
132 NDC1 55706
Affinity Capture-MS Homo sapiens
133 GLI2  
Proximity Label-MS Homo sapiens
134 HNRNPLL 92906
Two-hybrid Homo sapiens
135 SH3GLB1 51100
Co-fractionation Homo sapiens
136 MAF  
Affinity Capture-Western Homo sapiens
137 ZNRD1  
Biochemical Activity Homo sapiens
138 FHIT 2272
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
139 CAMK2D 817
Two-hybrid Homo sapiens
140 SMURF2 64750
Affinity Capture-Western Homo sapiens
141 XPO7 23039
Co-fractionation Homo sapiens
142 NUP85 79902
Affinity Capture-MS Homo sapiens
143 PPARGC1A  
Biochemical Activity Homo sapiens
144 NVL  
Two-hybrid Homo sapiens
145 RANGAP1 5905
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
146 NXT2  
Affinity Capture-MS Homo sapiens
147 TRIM3 10612
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
148 CLIP1 6249
Affinity Capture-MS Homo sapiens
149 SIAH2 6478
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
150 LCE2C  
Two-hybrid Homo sapiens
151 CTBP2 1488
Two-hybrid Homo sapiens
152 FMR1 2332
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
153 ARFGAP2 84364
Co-fractionation Homo sapiens
154 UCHL1 7345
Two-hybrid Homo sapiens
155 NUDCD3 23386
Two-hybrid Homo sapiens
156 GMCL1P1  
Two-hybrid Homo sapiens
157 TRIM33 51592
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
158 ROCK2 9475
Biochemical Activity Homo sapiens
159 CREM  
Two-hybrid Homo sapiens
160 SETDB1  
Two-hybrid Homo sapiens
161 LCE5A  
Two-hybrid Homo sapiens
162 XRCC1 7515
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
163 NCOR1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
164 AKAP17A  
Two-hybrid Homo sapiens
165 DPYSL2 1808
Biochemical Activity Homo sapiens
166 DDX24 57062
Biochemical Activity Homo sapiens
167 PUF60 22827
Two-hybrid Homo sapiens
168 TDP2 51567
Two-hybrid Homo sapiens
169 NUP93 9688
Affinity Capture-MS Homo sapiens
170 GCM1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
171 DCTD 1635
Two-hybrid Homo sapiens
172 LRSAM1 90678
Two-hybrid Homo sapiens
173 RCBTB2  
Two-hybrid Homo sapiens
174 BIRC3 330
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
175 SEPT1 1731
Two-hybrid Homo sapiens
176 PPCDC  
Two-hybrid Homo sapiens
177 TSN 7247
Two-hybrid Homo sapiens
178 SOX5 6660
Two-hybrid Homo sapiens
179 GTF2I 2969
Biochemical Activity Homo sapiens
180 XPO1 7514
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
181 JMJD6 23210
Co-fractionation Homo sapiens
182 SYMPK 8189
Biochemical Activity Homo sapiens
183 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
184 DDX21 9188
Biochemical Activity Homo sapiens
185 FHL3 2275
Two-hybrid Homo sapiens
186 ZBTB16  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
187 SUPT7L  
Biochemical Activity Homo sapiens
188 EGR2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
189 NCOR2  
Biochemical Activity Homo sapiens
190 CDR2L  
Two-hybrid Homo sapiens
191 Grm6  
Reconstituted Complex Rattus norvegicus
192 RNF115  
Two-hybrid Homo sapiens
193 AGTRAP 57085
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
194 SNRNP200 23020
Biochemical Activity Homo sapiens
195 ZEB2  
Biochemical Activity Homo sapiens
196 UBXN1 51035
Two-hybrid Homo sapiens
197 BTBD3  
Two-hybrid Homo sapiens
198 RAD18  
Two-hybrid Homo sapiens
199 AGR2 10551
Two-hybrid Homo sapiens
200 ALYREF 10189
Co-fractionation Homo sapiens
201 TRIM72  
Two-hybrid Homo sapiens
202 EGF 1950
Affinity Capture-Western Homo sapiens
203 HNRNPD 3184
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
204 KIF1B 23095
Affinity Capture-MS Homo sapiens
205 TP53BP1 7158
Co-localization Homo sapiens
206 SOX6  
Proximity Label-MS Homo sapiens
Biochemical Activity Homo sapiens
207 RC3H2  
Two-hybrid Homo sapiens
208 IKZF3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
209 PPARG 5468
FRET Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
210 PRKAA2 5563
Two-hybrid Homo sapiens
211 SREBF1 6720
Affinity Capture-Western Homo sapiens
212 RAD52  
Two-hybrid Homo sapiens
213 MX1 4599
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
214 DACH1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
215 EGFR 1956
Negative Genetic Homo sapiens
216 FUS 2521
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
217 TMEM194A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 IKZF1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
219 NAF1  
Two-hybrid Homo sapiens
220 TFG 10342
Two-hybrid Homo sapiens
221 ZCCHC7  
Two-hybrid Homo sapiens
222 RANBP9 10048
Affinity Capture-Western Homo sapiens
223 CDK2 1017
Affinity Capture-MS Homo sapiens
224 CORO2A  
Biochemical Activity Homo sapiens
225 PIAS1 8554
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
226 MYC  
Dosage Lethality Homo sapiens
227 UBE2E1  
Co-fractionation Homo sapiens
228 BLMH 642
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
229 EDF1 8721
Biochemical Activity Homo sapiens
230 BMI1  
Two-hybrid Homo sapiens
231 MECOM 2122
Biochemical Activity Homo sapiens
232 TMEM209 84928
Affinity Capture-MS Homo sapiens
233 MYB  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
234 ADAR 103
Biochemical Activity Homo sapiens
235 BEND5  
Two-hybrid Homo sapiens
236 CBLC  
Two-hybrid Homo sapiens
237 PA2G4 5036
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
238 TRIM38 10475
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
239 BIRC7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
240 MUL1  
Affinity Capture-Western Homo sapiens
241 NUTF2 10204
Affinity Capture-MS Homo sapiens
242 TERF2  
Biochemical Activity Homo sapiens
243 TRAF2 7186
Two-hybrid Homo sapiens
244 PARP1 142
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
245 PROP1  
Two-hybrid Homo sapiens
246 TP53 7157
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
247 NMI  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
248 ZBTB8A  
Two-hybrid Homo sapiens
249 CALU 813
Biochemical Activity Homo sapiens
250 SF3B4 10262
Co-fractionation Homo sapiens
251 KLF3  
Two-hybrid Homo sapiens
252 ZBTB26  
Two-hybrid Homo sapiens
253 SMAD4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
254 CDK6 1021
Affinity Capture-Western Homo sapiens
255 MAP2K1 5604
Biochemical Activity Homo sapiens
256 CDK1 983
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
257 POU2F1 5451
Two-hybrid Homo sapiens
258 ESR1  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
259 KLF5  
Biochemical Activity Homo sapiens
260 DDX39A 10212
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
261 EEF1A1P5 158078
Cross-Linking-MS (XL-MS) Homo sapiens
262 BCL2L1 598
Two-hybrid Homo sapiens
263 B2M 567
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 SSSCA1 10534
Two-hybrid Homo sapiens
265 TCF3  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
266 LONRF1  
Two-hybrid Homo sapiens
267 Ranbp2  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
268 TOPORS  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
269 KRAS 3845
Negative Genetic Homo sapiens
270 SH3KBP1 30011
Biochemical Activity Homo sapiens
271 MIPOL1  
Two-hybrid Homo sapiens
272 Nup107  
Affinity Capture-MS Mus musculus
273 KLHL12  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
274 ZBTB7A 51341
Biochemical Activity Homo sapiens
275 RANBP2 5903
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
276 CBS 875
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
277 Grm8  
Reconstituted Complex Rattus norvegicus
278 HNRNPC 3183
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
279 NOP58 51602
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
280 THRB 7068
Biochemical Activity Homo sapiens
281 RARRES3  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
282 TCF7L2  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
283 ADD3 120
Biochemical Activity Homo sapiens
284 HNRNPCL1 343069
Two-hybrid Homo sapiens
285 CAMSAP2  
Biochemical Activity Homo sapiens
286 ARL6IP1 23204
Two-hybrid Homo sapiens
287 SOX9  
Proximity Label-MS Homo sapiens
Biochemical Activity Homo sapiens
288 SOX10  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
289 Dnm1 140694
Reconstituted Complex Rattus norvegicus
290 ZNF618  
Two-hybrid Homo sapiens
291 TRIM54  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
292 HSF2  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
293 NR1I2  
Biochemical Activity Homo sapiens
294 RUVBL1 8607
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
295 TRIM28 10155
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
296 Trim32  
Affinity Capture-MS Mus musculus
297 MEF2A  
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
298 IQGAP1 8826
Biochemical Activity Homo sapiens
299 NUP210 23225
Affinity Capture-MS Homo sapiens
300 STAT3 6774
Proximity Label-MS Homo sapiens
301 RWDD3  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
302 RCC1 1104
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
303 RPS3A 6189
Biochemical Activity Homo sapiens
304 NHP2 55651
Biochemical Activity Homo sapiens
305 NR5A1  
Biochemical Activity Homo sapiens
306 CSNK2B 1460
Biochemical Activity Homo sapiens
307 KRTAP5-2  
Two-hybrid Homo sapiens
308 TLK2  
Two-hybrid Homo sapiens
309 FAS 355
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
310 PSME3 10197
Biochemical Activity Homo sapiens
311 NUP155 9631
Affinity Capture-MS Homo sapiens
312 CLK2 1196
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
313 VEZF1  
Two-hybrid Homo sapiens
314 CHMP1A 5119
Two-hybrid Homo sapiens
315 LMNA 4000
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
316 KPNA4 3840
Affinity Capture-MS Homo sapiens
317 KAT6B  
Biochemical Activity Homo sapiens
318 TAF10 6881
Biochemical Activity Homo sapiens
319 EXO1  
Biochemical Activity Homo sapiens
320 HIC1  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
321 RORB  
Two-hybrid Homo sapiens
322 CYP4F2  
Two-hybrid Homo sapiens
323 BLM 641
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
324 DNMT3A 1788
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
325 GOLGA2 2801
Two-hybrid Homo sapiens
326 NOP2 4839
Biochemical Activity Homo sapiens
327 SOCS6  
Two-hybrid Homo sapiens
328 USP8 9101
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
329 CHMP4B 128866
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
330 RAN 5901
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
331 ZNF837  
Two-hybrid Homo sapiens
332 Slc1a2  
Two-hybrid Mus musculus
333 HIST1H1E 3008
Cross-Linking-MS (XL-MS) Homo sapiens
334 UNC119 9094
Two-hybrid Homo sapiens
335 DHX9 1660
Two-hybrid Homo sapiens
336 ARL13B 200894
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
337 HDAC5 10014
Two-hybrid Homo sapiens
338 PAICS 10606
Two-hybrid Homo sapiens
339 LOC102724560 102724560
Two-hybrid Homo sapiens
340 ZBED1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
341 FLI1  
Two-hybrid Homo sapiens
342 EIF5A 1984
Biochemical Activity Homo sapiens
343 RBBP6 5930
Two-hybrid Homo sapiens
344 ZBTB2 57621
Two-hybrid Homo sapiens
345 ZHX1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
346 CDH4 1002
Biochemical Activity Homo sapiens
347 NFKBIA  
Biochemical Activity Homo sapiens
348 TAB2  
Biochemical Activity Homo sapiens
349 TRAF6 7189
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
350 CASP2  
Two-hybrid Homo sapiens
351 PTEN 5728
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
352 UHRF2  
Affinity Capture-Western Homo sapiens
353 MARCO  
Cross-Linking-MS (XL-MS) Homo sapiens
354 HNRNPA1 3178
Co-fractionation Homo sapiens
355 NUP214 8021
Affinity Capture-MS Homo sapiens
356 PDPK1 5170
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
357 TP73  
Two-hybrid Homo sapiens
358 KRTAP5-9  
Two-hybrid Homo sapiens
359 Grm4  
Reconstituted Complex Rattus norvegicus
360 NR5A2  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
361 MGRN1 23295
Two-hybrid Homo sapiens
362 HNF4A  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
363 DNMT3B  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
364 NOX5  
Biochemical Activity Homo sapiens
365 RABAC1 10567
Two-hybrid Homo sapiens
366 RXRA 6256
Biochemical Activity Homo sapiens
367 SPOP  
Two-hybrid Homo sapiens
368 RNF151  
Two-hybrid Homo sapiens
369 TP63  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
370 TOP1 7150
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
371 CFL2 1073
Two-hybrid Homo sapiens
372 MATR3 9782
Biochemical Activity Homo sapiens
373 RANBP1 5902
Affinity Capture-MS Homo sapiens
374 SEH1L 81929
Affinity Capture-MS Homo sapiens
375 SEPT7 989
Co-fractionation Homo sapiens
376 RNF185  
Two-hybrid Homo sapiens
377 RBBP5 5929
Biochemical Activity Homo sapiens
378 TSC22D3  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
379 CHUK 1147
Biochemical Activity Homo sapiens
380 XRCC5 7520
Biochemical Activity Homo sapiens
381 SUMO1 7341
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
FRET Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
382 HIF1A 3091
Biochemical Activity Homo sapiens
383 DZIP3  
Two-hybrid Homo sapiens
384 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
385 NUP205 23165
Affinity Capture-MS Homo sapiens
386 CRABP2 1382
Affinity Capture-Western Homo sapiens
387 MRPL53  
Co-fractionation Homo sapiens
388 HIPK3 10114
Two-hybrid Homo sapiens
389 DDX39B 7919
Two-hybrid Homo sapiens
390 HNRNPM 4670
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
391 MKRN3  
Two-hybrid Homo sapiens
392 SHFM1 7979
Affinity Capture-MS Homo sapiens
393 HSPB1 3315
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
394 CREBBP  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
395 LCE3B  
Two-hybrid Homo sapiens
396 DDX58 23586
Affinity Capture-RNA Homo sapiens
397 MYBBP1A 10514
Biochemical Activity Homo sapiens
398 PCNA 5111
Biochemical Activity Homo sapiens
399 ZNF646  
Two-hybrid Homo sapiens
400 KDM1A 23028
Biochemical Activity Homo sapiens
401 NDUFA2 4695
Co-fractionation Homo sapiens
402 GLUL 2752
Two-hybrid Homo sapiens
403 TRIM23 373
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
404 RNF111 54778
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
405 RPL8 6132
Biochemical Activity Homo sapiens
406 RPRD1B 58490
Two-hybrid Homo sapiens
407 FOXM1  
Biochemical Activity Homo sapiens
408 SUMO3 6612
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
409 AR 367
Two-hybrid Homo sapiens
Phenotypic Enhancement Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
410 CASP8AP2  
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
411 SSRP1 6749
Biochemical Activity Homo sapiens
412 ZNF408  
Two-hybrid Homo sapiens
413 CACYBP 27101
Affinity Capture-Western Homo sapiens
414 CEBPD  
Biochemical Activity Homo sapiens
415 CDKN2A 1029
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
416 CAPN2 824
Affinity Capture-Western Homo sapiens
417 SIAH1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
418 UBE2H 7328
Affinity Capture-MS Homo sapiens
419 REC8  
Affinity Capture-Western Homo sapiens
420 RIT1 6016
Negative Genetic Homo sapiens
421 XIAP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
422 SCNN1A  
Two-hybrid Homo sapiens
423 CSK 1445
Biochemical Activity Homo sapiens
424 TNPO1 3842
Affinity Capture-MS Homo sapiens
425 TRIP13 9319
Two-hybrid Homo sapiens
426 CARD9 64170
Two-hybrid Homo sapiens
427 KPNB1 3837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
428 ISY1 57461
Affinity Capture-MS Homo sapiens
429 CD2AP 23607
Biochemical Activity Homo sapiens
430 TSG101 7251
Co-fractionation Homo sapiens
431 HABP4  
Two-hybrid Homo sapiens
432 CHFR  
Biochemical Activity Homo sapiens
433 ZIC1  
Two-hybrid Homo sapiens
434 TRIM55  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
435 ZBTB1  
Biochemical Activity Homo sapiens
436 HIPK1 204851
Two-hybrid Homo sapiens
437 APP 351
Biochemical Activity Homo sapiens
438 TAF5  
Biochemical Activity Homo sapiens
439 DTL  
Affinity Capture-MS Homo sapiens
440 Grm7  
Reconstituted Complex Rattus norvegicus
441 USP36  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
442 WAS 7454
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
443 TOP2A 7153
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
444 RNF10  
Two-hybrid Homo sapiens
445 SEMA6A  
Biochemical Activity Homo sapiens
446 SP3  
Two-hybrid Homo sapiens
447 SPECC1L 23384
Two-hybrid Homo sapiens
448 TBL1XR1 79718
Biochemical Activity Homo sapiens
449 NDUFA7 4701
Co-fractionation Homo sapiens
450 TSNAX 7257
Biochemical Activity Homo sapiens
451 TFAP2C 7022
Two-hybrid Homo sapiens
452 HGS 9146
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
453 PSMD9 5715
Co-fractionation Homo sapiens
454 TDG 6996
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
455 HMGA1 3159
Affinity Capture-Western Homo sapiens
456 UBQLN1 29979
Two-hybrid Homo sapiens
457 NR1H2  
Two-hybrid Homo sapiens
458 ADARB1 104
Two-hybrid Homo sapiens
459 RAD51  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
460 RNF133  
Two-hybrid Homo sapiens
461 PRKRA 8575
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
462 SARNP 84324
Co-fractionation Homo sapiens
463 HNRNPK 3190
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
464 CDCA8 55143
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
465 DNM1 1759
Two-hybrid Homo sapiens
466 CHD3 1107
Two-hybrid Homo sapiens
467 NEDD4 4734
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
468 MEF2C  
Biochemical Activity Homo sapiens
469 PSMC3 5702
Biochemical Activity Homo sapiens
470 IMPDH1 3614
Two-hybrid Homo sapiens
471 SETD8  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
472 TRIM41 90933
Two-hybrid Homo sapiens
473 Rcc1  
Affinity Capture-MS Mus musculus
474 Mafb  
Biochemical Activity Mus musculus
475 ZNF451 26036
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
476 HMGN2 3151
Biochemical Activity Homo sapiens
477 NONO 4841
Biochemical Activity Homo sapiens
478 ATF2  
Two-hybrid Homo sapiens
Far Western Homo sapiens
479 DPPA2  
Two-hybrid Homo sapiens
480 CEBPE  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
481 UBE2I 7329
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
482 LCE1D  
Two-hybrid Homo sapiens
483 SREBF2 6721
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
484 C16orf58 64755
Two-hybrid Homo sapiens
485 DDX5 1655
Biochemical Activity Homo sapiens
486 TAF12  
Biochemical Activity Homo sapiens
487 PIAS2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
488 MLX  
Two-hybrid Homo sapiens
489 SUMO2 6613
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
490 SRF  
Biochemical Activity Homo sapiens
491 ATF3  
Biochemical Activity Homo sapiens
492 PML 5371
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
493 IKZF5 64376
Two-hybrid Homo sapiens
494 RFPL3  
Two-hybrid Homo sapiens
495 TATDN1 83940
Co-fractionation Homo sapiens
496 RAD54L2  
Two-hybrid Homo sapiens
497 CEBPA  
Protein-peptide Homo sapiens
498 DAXX  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
499 DDX1 1653
Co-fractionation Homo sapiens
500 RPS6KA6 27330
Biochemical Activity Homo sapiens
501 MAT2A 4144
Biochemical Activity Homo sapiens
502 BCL11A 53335
Biochemical Activity Homo sapiens
503 NUMA1 4926
Affinity Capture-MS Homo sapiens
504 SFPQ 6421
Biochemical Activity Homo sapiens
505 MITF  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
506 ZNF420  
Affinity Capture-Western Homo sapiens
507 Nup98  
Affinity Capture-MS Mus musculus
508 NR3C1 2908
Biochemical Activity Homo sapiens
509 NAT10 55226
Biochemical Activity Homo sapiens
510 SRSF1 6426
Affinity Capture-Western Homo sapiens
511 PEX10  
Two-hybrid Homo sapiens
512 RBMS1 5937
Co-fractionation Homo sapiens
513 MAP3K1 4214
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
514 PIAS3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
515 NACC1 112939
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
516 RPL7 6129
Biochemical Activity Homo sapiens
517 TRAF3 7187
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
518 SUZ12  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
519 SART1 9092
Biochemical Activity Homo sapiens
520 ZC3H10  
Two-hybrid Homo sapiens
521 NXF1 10482
Affinity Capture-MS Homo sapiens
522 SETBP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
523 AURKB 9212
Biochemical Activity Homo sapiens
524 JUN 3725
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
525 PAX5  
Two-hybrid Homo sapiens
526 UBE2D2 7322
Co-fractionation Homo sapiens
527 XPO4 64328
Affinity Capture-MS Homo sapiens
528 FOS 2353
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
529 PPARA  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
530 RAD54B  
Two-hybrid Homo sapiens
531 TRIM27  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
532 KAT5  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
533 Scnn1g  
Reconstituted Complex Rattus norvegicus
534 FATE1  
Two-hybrid Homo sapiens
535 NOL6 65083
Biochemical Activity Homo sapiens
536 ZMYM2  
Two-hybrid Homo sapiens
537 MDM2  
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
538 KLHL2 11275
Two-hybrid Homo sapiens
539 SATB1 6304
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
540 MAPK1IP1L 93487
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
541 TFAP2B  
Two-hybrid Homo sapiens
542 CLDN2 9075
Two-hybrid Homo sapiens
543 PDLIM7 9260
Two-hybrid Homo sapiens
544 ARRB2 409
Biochemical Activity Homo sapiens
545 HSPB2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
546 BKRF1  
Affinity Capture-Western
Biochemical Activity
547 KAT2A  
Biochemical Activity Homo sapiens
548 TRPS1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
549 CFTR 1080
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
550 COG1 9382
Biochemical Activity Homo sapiens
551 RGPD2  
Affinity Capture-MS Homo sapiens
552 PPM1J  
Reconstituted Complex Homo sapiens
553 SOX4  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
554 ELK1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
555 HDAC1 3065
Biochemical Activity Homo sapiens
556 CHD4 1108
Biochemical Activity Homo sapiens
557 NUP35 129401
Affinity Capture-MS Homo sapiens
558 CREB1  
Two-hybrid Homo sapiens
559 NUP98 4928
Affinity Capture-MS Homo sapiens
560 GIPC2 54810
Two-hybrid Homo sapiens
561 THAP1  
Two-hybrid Homo sapiens
562 NUP107 57122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
563 ZNF106  
Two-hybrid Homo sapiens
564 ZBTB9  
Two-hybrid Homo sapiens
565 HSF1  
Biochemical Activity Homo sapiens
566 IPO13 9670
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
567 HIPK2 28996
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
568 HIRA  
Biochemical Activity Homo sapiens
569 KCTD1 284252
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
570 HNRNPU 3192
Biochemical Activity Homo sapiens
571 TRIM29 23650
Two-hybrid Homo sapiens
572 HSF2BP  
Biochemical Activity Homo sapiens
View the network image/svg+xml
 Pathways in which UBE2I is involved
PathwayEvidenceSource
Antiviral mechanism by IFN-stimulated genes TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle, Mitotic TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Disease IEA Reactome
Disease TAS Reactome
DNA Double Strand Break Response TAS Reactome
DNA Double-Strand Break Repair TAS Reactome
DNA Repair TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Formation of Incision Complex in GG-NER TAS Reactome
Gene expression (Transcription) IEA Reactome
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway IEA Reactome
Generic Transcription Pathway TAS Reactome
Global Genome Nucleotide Excision Repair (GG-NER) TAS Reactome
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) TAS Reactome
Homology Directed Repair TAS Reactome
Immune System TAS Reactome
Infectious disease IEA Reactome
Infectious disease TAS Reactome
Interferon Signaling TAS Reactome
Late SARS-CoV-2 Infection Events IEA Reactome
M Phase TAS Reactome
Maturation of nucleoprotein TAS Reactome
Maturation of nucleoprotein IEA Reactome
Meiosis IEA Reactome
Meiotic synapsis IEA Reactome
Metabolism TAS Reactome
Metabolism of lipids TAS Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of steroids TAS Reactome
Mitotic Anaphase TAS Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Negative regulation of activity of TFAP2 (AP-2) family transcription factors IEA Reactome
Negative regulation of activity of TFAP2 (AP-2) family transcription factors TAS Reactome
Nuclear Envelope (NE) Reassembly TAS Reactome
Nucleotide Excision Repair TAS Reactome
PKR-mediated signaling TAS Reactome
Post-translational protein modification TAS Reactome
Post-translational protein modification IEA Reactome
Postmitotic nuclear pore complex (NPC) reformation TAS Reactome
Processing and activation of SUMO IEA Reactome
Processing and activation of SUMO TAS Reactome
Processing of DNA double-strand break ends TAS Reactome
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks TAS Reactome
Regulation of endogenous retroelements IEA Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins IEA Reactome
Reproduction IEA Reactome
RNA Polymerase II Transcription IEA Reactome
RNA Polymerase II Transcription TAS Reactome
SARS-CoV Infections IEA Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-1 Infection TAS Reactome
SARS-CoV-1 targets host intracellular signalling and regulatory pathways TAS Reactome
SARS-CoV-1-host interactions TAS Reactome
SARS-CoV-2 Infection IEA Reactome
SUMO E3 ligases SUMOylate target proteins TAS Reactome
SUMO E3 ligases SUMOylate target proteins IEA Reactome
SUMO is transferred from E1 to E2 (UBE2I, UBC9) IEA Reactome
SUMO is transferred from E1 to E2 (UBE2I, UBC9) TAS Reactome
SUMOylation TAS Reactome
SUMOylation IEA Reactome
SUMOylation of chromatin organization proteins TAS Reactome
SUMOylation of chromatin organization proteins IEA Reactome
SUMOylation of DNA damage response and repair proteins TAS Reactome
SUMOylation of DNA methylation proteins TAS Reactome
SUMOylation of DNA methylation proteins IEA Reactome
SUMOylation of DNA replication proteins TAS Reactome
SUMOylation of DNA replication proteins IEA Reactome
SUMOylation of immune response proteins TAS Reactome
SUMOylation of intracellular receptors TAS Reactome
SUMOylation of intracellular receptors IEA Reactome
SUMOylation of nuclear envelope proteins TAS Reactome
SUMOylation of RNA binding proteins TAS Reactome
SUMOylation of SUMOylation proteins TAS Reactome
SUMOylation of transcription cofactors TAS Reactome
SUMOylation of transcription cofactors IEA Reactome
SUMOylation of transcription factors IEA Reactome
SUMOylation of transcription factors TAS Reactome
SUMOylation of ubiquitinylation proteins TAS Reactome
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors IEA Reactome
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors TAS Reactome
Translation of Structural Proteins TAS Reactome
Translation of Structural Proteins IEA Reactome
Viral Infection Pathways IEA Reactome
Viral Infection Pathways TAS Reactome
Vitamin D (calciferol) metabolism TAS Reactome





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