Experiment description of studies that identified PDZK1 in exosomes

1 Experiment ID 63 MISEV standards ✘ EV Biophysical techniques ✔ AQP2 EV Enriched markers ✘ EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19056867     Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

2 Experiment ID 196 MISEV standards ✔ EM EV Biophysical techniques ✔ Alix|TSG101|HSP70|CD9 EV Enriched markers ✘ EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 22418980     Organism Homo sapiens Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G. Journal name Kidney Int Publication year 2012 Sample Urine Sample name Urine - Normal high density Isolation/purification methods Differential centrifugation Sucrose cushion Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 197 MISEV standards ✔ EM EV Biophysical techniques ✔ Alix|TSG101|HSP70|CD9 EV Enriched markers ✘ EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 22418980     Organism Homo sapiens Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G. Journal name Kidney Int Publication year 2012 Sample Urine Sample name Urine - Normal low density Isolation/purification methods Differential centrifugation Sucrose cushion Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for PDZK1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 AKAP10 11216 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 2 PDZK1IP1 10158 Invivo Homo sapiens Invitro Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 3 ABCC2 1244 Two-hybrid Homo sapiens 4 PEX5 5830 Two-hybrid Homo sapiens 5 GFAP 2670 Two-hybrid Homo sapiens 6 UBE2I 7329 Two-hybrid Homo sapiens 7 SLC9A3R1 9368 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 8 CFTR   Invivo Homo sapiens Invivo Homo sapiens Invitro Homo sapiens Invitro Homo sapiens 9 SLC17A1   Two-hybrid Homo sapiens 10 SLC22A4 6583 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 11 FARP2 9855 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 12 SLK 9748 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 13 SLC34A3   Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 14 SLC9A3 6550 Two-hybrid Homo sapiens 15 SCARB1 949 Affinity Capture-MS Homo sapiens Invivo Homo sapiens Affinity Capture-Western Homo sapiens 16 SLC9A3R2 9351 Two-hybrid Homo sapiens 17 CLCN3 1182 Invitro Homo sapiens Invivo Homo sapiens 18 SLC22A12 116085 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens View the network

Pathways in which PDZK1 is involved

No pathways found