Gene description for IPO13
Gene name importin 13
Gene symbol IPO13
Other names/aliases IMP13
KAP13
LGL2
RANBP13
Species Homo sapiens
 Database cross references - IPO13
ExoCarta ExoCarta_9670
Vesiclepedia VP_9670
Entrez Gene 9670
HGNC 16853
MIM 610411
UniProt O94829  
 IPO13 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for IPO13
Molecular Function
    protein binding GO:0005515 IPI
    small GTPase binding GO:0031267 IEA
Biological Process
    protein import into nucleus GO:0006606 IBA
    protein import into nucleus GO:0006606 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified IPO13 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for IPO13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TGOLN2 10618
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 UPK2 7379
Affinity Capture-MS Homo sapiens
3 F2RL1  
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 B3GALT2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 CD40 958
Affinity Capture-MS Homo sapiens
7 KRT73 319101
Affinity Capture-MS Homo sapiens
8 C5AR1  
Affinity Capture-MS Homo sapiens
9 PAX6  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
10 ALX1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
11 ALDH3A2 224
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 ST8SIA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 ICAM2 3384
Affinity Capture-MS Homo sapiens
14 GPR17 2840
Affinity Capture-MS Homo sapiens
15 RBM8A 9939
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
16 MOCS2  
Affinity Capture-MS Homo sapiens
17 FPR1  
Affinity Capture-MS Homo sapiens
18 OPALIN  
Affinity Capture-MS Homo sapiens
19 HIGD1A 25994
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 MFSD4  
Affinity Capture-MS Homo sapiens
21 EIF1AX 1964
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
22 LRRC25  
Affinity Capture-MS Homo sapiens
23 PROKR1  
Affinity Capture-MS Homo sapiens
24 NPTN 27020
Affinity Capture-MS Homo sapiens
25 GZMH  
Affinity Capture-MS Homo sapiens
26 CLEC2D  
Affinity Capture-MS Homo sapiens
27 RFPL3  
Affinity Capture-Western Homo sapiens
28 SYNPO2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
29 MGARP  
Affinity Capture-MS Homo sapiens
30 SLAMF1 6504
Affinity Capture-MS Homo sapiens
31 PITX1  
Two-hybrid Homo sapiens
32 HS3ST4  
Affinity Capture-MS Homo sapiens
33 PDLIM7 9260
Affinity Capture-MS Homo sapiens
34 NPY2R  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 EGFR 1956
Affinity Capture-MS Homo sapiens
36 HCST  
Affinity Capture-MS Homo sapiens
37 RPL5 6125
Reconstituted Complex Homo sapiens
38 KLRB1  
Affinity Capture-MS Homo sapiens
39 HK2 3099
Affinity Capture-MS Homo sapiens
40 THOC6 79228
Co-fractionation Homo sapiens
41 STOM 2040
Affinity Capture-MS Homo sapiens
42 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
43 DDX58 23586
Affinity Capture-RNA Homo sapiens
44 NPSR1  
Two-hybrid Homo sapiens
45 SIGLECL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 SPACA1 81833
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 PSMA1 5682
Two-hybrid Homo sapiens
48 NXF1 10482
Affinity Capture-RNA Homo sapiens
49 CRX  
Reconstituted Complex Homo sapiens
50 VSIG4  
Affinity Capture-MS Homo sapiens
51 CHRM3 1131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 PWP2 5822
Co-fractionation Homo sapiens
53 PBX4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
54 UBE2I 7329
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
55 NUP50 10762
Reconstituted Complex Homo sapiens
56 XPO4 64328
Co-fractionation Homo sapiens
57 B3GNT2 10678
Affinity Capture-MS Homo sapiens
58 MYC  
Affinity Capture-MS Homo sapiens
59 RAN 5901
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
60 NTRK1 4914
Affinity Capture-MS Homo sapiens
61 GPR45  
Affinity Capture-MS Homo sapiens
62 CIAPIN1 57019
Affinity Capture-MS Homo sapiens
63 HLA-B 3106
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 GPR182  
Affinity Capture-MS Homo sapiens
65 HMBOX1  
Two-hybrid Homo sapiens
66 ESRRA  
Co-fractionation Homo sapiens
67 SLC25A22  
Affinity Capture-MS Homo sapiens
68 GK  
Two-hybrid Homo sapiens
69 GML  
Affinity Capture-MS Homo sapiens
70 OPRM1 4988
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 KRAS 3845
Negative Genetic Homo sapiens
72 RANBP1 5902
Affinity Capture-MS Homo sapiens
73 P2RY10  
Affinity Capture-MS Homo sapiens
74 MAGOH 4116
Reconstituted Complex Homo sapiens
75 ITFG3 83986
Affinity Capture-MS Homo sapiens
76 P2RY8  
Affinity Capture-MS Homo sapiens
77 PAX3  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
78 FFAR1  
Affinity Capture-MS Homo sapiens
79 GPR55  
Affinity Capture-MS Homo sapiens
80 TACSTD2 4070
Affinity Capture-MS Homo sapiens
81 NDUFS7 374291
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IPO13 is involved
No pathways found





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