Gene description for OPRM1
Gene name	opioid receptor, mu 1
Gene symbol	OPRM1
Other names/aliases	LMOR M-OR-1 MOP MOR MOR1 OPRM
Species	Homo sapiens
Database cross references - OPRM1
ExoCarta	ExoCarta_4988
Vesiclepedia	VP_4988
Entrez Gene	4988
HGNC	8156
MIM	600018
UniProt	P35372
OPRM1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for OPRM1

Molecular Function     G-protein alpha-subunit binding GO:0001965 IBA     G-protein alpha-subunit binding GO:0001965 IDA     G protein-coupled receptor activity GO:0004930 ISS     beta-endorphin receptor activity GO:0004979 IBA     beta-endorphin receptor activity GO:0004979 IMP     voltage-gated calcium channel activity GO:0005245 ISS     protein binding GO:0005515 IPI     G-protein beta-subunit binding GO:0031681 IBA     morphine receptor activity GO:0038047 IBA     morphine receptor activity GO:0038047 ISS     neuropeptide binding GO:0042923 IBA Biological Process     G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 TAS     adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway GO:0007197 ISS     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 ISS     positive regulation of cytosolic calcium ion concentration GO:0007204 IDA     neuropeptide signaling pathway GO:0007218 IBA     sensory perception GO:0007600 NAS     negative regulation of cell population proliferation GO:0008285 TAS     sensory perception of pain GO:0019233 IBA     sensory perception of pain GO:0019233 ISS     G protein-coupled opioid receptor signaling pathway GO:0038003 IBA     G protein-coupled opioid receptor signaling pathway GO:0038003 ISS     positive regulation of cAMP-mediated signaling GO:0043950 IDA     negative regulation of cAMP-mediated signaling GO:0043951 IDA     negative regulation of nitric oxide biosynthetic process GO:0045019 IDA     positive regulation of nitric oxide biosynthetic process GO:0045429 IDA     behavioral response to ethanol GO:0048149 IMP     positive regulation of neurogenesis GO:0050769 ISS     negative regulation of cytosolic calcium ion concentration GO:0051481 IDA     negative regulation of Wnt protein secretion GO:0061358 IMP     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS     calcium ion transmembrane transport GO:0070588 IEA     cellular response to morphine GO:0071315 IEA     regulation of cellular response to stress GO:0080135 IMP     regulation of NMDA receptor activity GO:2000310 ISS Subcellular Localization     endosome GO:0005768 ISS     endoplasmic reticulum GO:0005783 TAS     Golgi apparatus GO:0005794 TAS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS     axon GO:0030424 ISS     dendrite GO:0030425 ISS     neuron projection GO:0043005 IBA     perikaryon GO:0043204 IEA     synapse GO:0045202 IEA