Gene description for OPRM1
Gene name	opioid receptor, mu 1
Gene symbol	OPRM1
Other names/aliases	LMOR M-OR-1 MOP MOR MOR1 OPRM
Species	Homo sapiens
Database cross references - OPRM1
ExoCarta	ExoCarta_4988
Vesiclepedia	VP_4988
Entrez Gene	4988
HGNC	8156
MIM	600018
UniProt	P35372
OPRM1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for OPRM1

Molecular Function     protein domain specific binding GO:0019904 IEA     filamin binding GO:0031005 IEA     morphine receptor activity GO:0038047 ISS     G-protein coupled receptor activity GO:0004930 ISS     G-protein beta-subunit binding GO:0031681 IBA     protein binding GO:0005515 IPI     neuropeptide binding GO:0042923 IBA     beta-endorphin receptor activity GO:0004979 IMP     voltage-gated calcium channel activity GO:0005245 ISS     G-protein alpha-subunit binding GO:0001965 IDA Biological Process     adenylate cyclase-activating dopamine receptor signaling pathway GO:0007191 IEA     sensory perception GO:0007600 NAS     negative regulation of adenylate cyclase activity GO:0007194 ISS     cellular response to stress GO:0033554 IMP     response to food GO:0032094 IEA     negative regulation of cytosolic calcium ion concentration GO:0051481 IDA     neuropeptide signaling pathway GO:0007218 IMP     positive regulation of neurogenesis GO:0050769 ISS     regulation of sensory perception of pain GO:0051930 IEA     synaptic transmission GO:0007268 IBA     negative regulation of nitric oxide biosynthetic process GO:0045019 IDA     positive regulation of nitric oxide biosynthetic process GO:0045429 IDA     sensory perception of pain GO:0019233 ISS     negative regulation of cell proliferation GO:0008285 TAS     response to growth factor GO:0070848 IEA     regulation of N-methyl-D-aspartate selective glutamate receptor activity GO:2000310 ISS     positive regulation of cAMP-mediated signaling GO:0043950 IDA     cellular response to morphine GO:0071315 IBA     negative regulation of Wnt protein secretion GO:0061358 IMP     adenylate cyclase-inhibiting opioid receptor signaling pathway GO:0031635 IEA     locomotory behavior GO:0007626 IEA     response to cocaine GO:0042220 IEA     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS     positive regulation of cytosolic calcium ion concentration GO:0007204 IDA     calcium ion transmembrane transport GO:0070588 IEA     opioid receptor signaling pathway GO:0038003 IBA     acute inflammatory response to antigenic stimulus GO:0002438 IEA     G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 TAS     negative regulation of cAMP-mediated signaling GO:0043951 IDA     regulation of excitatory postsynaptic membrane potential GO:0060079 IEA     positive regulation of appetite GO:0032100 IEA     response to lipopolysaccharide GO:0032496 IEA     behavioral response to ethanol GO:0048149 IMP     wound healing GO:0042060 IEA     phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200 ISS Subcellular Localization     neuron projection GO:0043005 IBA     dendrite cytoplasm GO:0032839 IEA     perikaryon GO:0043204 IEA     integral component of plasma membrane GO:0005887 TAS     focal adhesion GO:0005925 IEA     plasma membrane GO:0005886 TAS     Golgi apparatus GO:0005794 TAS     cytosol GO:0005829 IDA     dendrite membrane GO:0032590 IEA     endoplasmic reticulum GO:0005783 TAS     sarcolemma GO:0042383 IEA     membrane raft GO:0045121 IEA